Alexander Kanitz: Difference between revisions

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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;8093 Zurich<br/>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;8093 Zurich<br/>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Switzerland<br/>  
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Switzerland<br/>  
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[http://maps.google.com/maps?f=q&hl=en&q=Wolfgang-Pauli-Strasse+10,+8049+Zurich,+Zurich,+Switzerland&sll=47.388089,8.538357&sspn=0.010053,0.027723&ie=UTF8&cd=1&geocode=0,47.407532,8.507197&ll=47.406642,8.509533&spn=0.010049,0.027723&t=h&z=16 Google Maps link]<br/>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[http://maps.google.com/maps/ms?hl=en&ie=UTF8&cd=1&geocode=0,47.407532,8.507197&t=h&msa=0&ll=47.40625,8.510113&spn=0.020099,0.055361&z=15&msid=113355392983449396379.0004620333c5385a6a663 Google Maps link]<br/>
*Email: [mailto:alexander.kanitz@pharma.ethz.ch alexander.kanitz@pharma.ethz.ch]
*Email: [mailto:alexander.kanitz@pharma.ethz.ch alexander.kanitz@pharma.ethz.ch]
*Tel: +41 44 633 36 34
*Tel: +41 44 633 36 34

Revision as of 12:58, 3 February 2009

Contact Info

  • ETH Zurich

     Department of Chemistry and Applied Biosciences
     Institute of Pharmaceutical Sciences / Pharmacogenomics Unit
     Wolfgang Pauli-Strasse 10
     8093 Zurich
     Switzerland
     Google Maps link

Research interests

I am interested in post-transcriptional regulatory networks, particularly the regulation of mRNA translation, localization and stability by RNA-binding proteins and non-coding RNAs ("mRNP code"). In our lab we are trying to decipher sequence or structural RNA regulatory elements with a primary focus on the human and yeast 3'UTRomes.

Current position

I am a grad student in the Gerber Lab at the ETH Zurich, working on post-transcriptional gene regulation. Tentative title of the project: "Systematic Analysis of the Crosstalk between Regulatory RNA-Binding Proteins and the MicroRNA Machinery".
I was recruited through the Molecular Life Sciences program of the Life Science Zurich Graduate School.
Furthermore, I am a founding member of the miR Network Zurich (MiNZ).

Previous labs

  • 2004-2005 - Seppen Lab, AMC Liver Center, University of Amsterdam, The Netherlands: "Lentiviral Gene Transfer of Chemically Inducible Hepatocyte Growth Factor Receptor and Liver Re-Targeting of Lentiviral Particles" / Supervisors: Dr. Jurgen Seppen, Prof. Ronald P.J. Oude-Elferink
  • 2004 - Skerra Lab, Institute of Biological Chemistry, Technical University of Munich, Germany: "Production and characterization of the enzymatically active domain of the endolysine Ply500 isolated from Listeria monocytogenes-bacteriophage A 500" / Supervisors: Dr. Ingo P. Korndörfer, Prof. Arne Skerra

Education

Publications

  1. Galgano A, Forrer M, Jaskiewicz L, Kanitz A, Zavolan M, and Gerber AP. Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system. PLoS One. 2008 Sep 8;3(9):e3164. DOI:10.1371/journal.pone.0003164 | PubMed ID:18776931 | HubMed [Paper3]
  2. Korndörfer IP, Kanitz A, Danzer J, Zimmer M, Loessner MJ, and Skerra A. Structural analysis of the L-alanoyl-D-glutamate endopeptidase domain of Listeria bacteriophage endolysin Ply500 reveals a new member of the LAS peptidase family. Acta Crystallogr D Biol Crystallogr. 2008 Jun;64(Pt 6):644-50. DOI:10.1107/S0907444908007890 | PubMed ID:18560152 | HubMed [Paper2]
  3. Markusic DM, Kanitz A, Oude-Elferink RP, and Seppen J. Preferential gene transfer of lentiviral vectors to liver-derived cells, using a hepatitis B peptide displayed on GP64. Hum Gene Ther. 2007 Jul;18(7):673-9. DOI:10.1089/hum.2007.027 | PubMed ID:17630838 | HubMed [Paper1]
All Medline abstracts: PubMed | HubMed


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