Registry of Standard Biological Models/Basic Component Models/Activated Promoter: Difference between revisions

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==CellML structure (CellML 1.1 spec)==
==CellML structure (CellML 1.1 spec)==
*'''Component''': ConstitutivePromoter
*'''Component''': ActivatedPromoter
*'''Units''':  
*'''Units''':  
**TBD
**TBD

Revision as of 18:20, 7 September 2006

ID: Activated Promoter

  • Description: Promoter activated by an activator molecule
  • Hypothesis:
    • Simple binding of the activator on the promoter (monod-type equation)
    • Continuous transcription rate with an existing maximum rate of transcription
    • Transcription rate depends on number of gene copies
  • Inputs:
    • nb-gene-copies
    • activator
  • Outputs:
    • PoPs
  • Internal parameters:
    • max-transcription-rate (per gene copy)
    • sensitivity

CellML structure (CellML 1.1 spec)

  • Component: ActivatedPromoter
  • Units:
    • TBD
  • Variables:
    • nbGeneCopies (public interface = in / init value = 1.0)
    • maxTranscriptionRate (public interface = none / init value = XXX)
    • sensitivity (public interface = none / init value = XXX)
    • activator (public interface = in )
    • PoPsOUT (public interface = out / init value = 0.)
  • MathML
    • <amsmath>PoPsOUT = \frac{maxTranscriptionRate*nbGenesCopies*activator}{sensitivity + activator}</amsmath>


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