OHSU Knight Cancer Institute Research Groups:OCI Cancer Journal Club: Difference between revisions

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*When and where we meet
*When and where we meet
:MacHall 2136
:MacHall 2136
:Thursdays noon-1 PM
:Tuesdays noon-1 PM
:Lunch provided by KCI
:Lunch provided by KCI
*Organizer contact information:  
*Organizer contact information:  
: Rosie Sears-searsr@ohsu.edu
: Mushui Dai-daim@ohsu.edu
: David Qian-qianzh@ohsu.edu
: Charlie Lopez- lopezc@ohsu.edu
: Charlie Lopez- lopezc@ohsu.edu


Line 50: Line 51:


|--
|--
|9/27/2012
|09/27/2016
|Rosalie Sears
|
|Organization
|Organization
|
|
|--
|--
|10/4/2012
|10/4/2016
|Brittany Allen-Petersen
|Kevin Watanabe-Smith
|Tumourmicro-environment elicits innate resistance to RAF inhibitors through HGF secretion
|
|[http://www.nature.com/nature/journal/v487/n7408/full/nature11183.html Straussman et al]
|
|--
|--
|10/11/2012
|10/11/2016
|Ellen Langer
|Timothy Carey
|A restricted cell population propagates glioblastoma growth after chemotherapy
|
|[http://openwetware.org/images/3/3a/Chen_Nature_2012.pdf Chen, et al] Additional vivo detection papers [http://www.ncbi.nlm.nih.gov/pubmed/22854777 1] [http://www.ncbi.nlm.nih.gov/pubmed/22855427 2]
|
|--
|--
|10/18/2012
|10/18/2016
|Yulong Su
|Xiao-Xin Sun
|Transcriptional Amplification in Tumor Cells with Elevated c-Myc;
|
c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells
|
|[http://www.sciencedirect.com/science/article/pii/S0092867412010574 Lin 2012]
[http://www.sciencedirect.com/science/article/pii/S0092867412011014 Nie 2012]
|--
|--
|10/25/2012
|10/25/2016
|****CANCELLED****  Dr. Charles Lopez
|Lilli Klug
| Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
|
|[http://openwetware.org/images/a/a5/Nature11156.pdf Misale at. al] [http://openwetware.org/images/3/33/Nature11156-s1.pdf supp. info]
|
|--  
|--  
|11/1/2012
|11/1/2016
|Asia Mitchell
|Marilynn Chow
|Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks
|
|[http://www.sciencedirect.com/science/article/pii/S0092867412004199]
|
|--
|11/8/2016
|Sherif Abdelhamed
|
|
|--
|--
|11/8/2012
|11/15/2016
|Yuhan Wang
|Chelsea Jenkins
|"Loss of 5-Hydroxymethylcytosine is an Epigenetic Hallmark of Melanoma"
|
|[http://openwetware.org/images/4/4e/Journal_Club_paper-5hmc.pdf]
|  
|--
|--
|11/15/2012
|11/22/2016
|Tyler Risom
|Ben Doron
|Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer
|
| [http://openwetware.org/images/8/85/PI3K_and_Parp_1.full.pdf Ashish et. al.] [http://openwetware.org/images/8/82/PI3K_and_Parp_2.full.pdf Yasir et al]
|
|--
|11/29/2016
|David Edwards
|
|
|--
|12/06/2016
|Cymon Kirsh
|
|
|--
|12/13/2016
|NO JC
|
|
|--
|--
|11/22/2012
|12/20/2016
|xxxxxxxxxx
|NO JC
|THANKSGIVING, NO JOURNAL CLUB
|
|xxxxxxxxxx
|
|--
|--
|11/29/2012
|12/27/2016
|Dr. Swarnali Acharyya, a CDB/Knight faculty candidate seminar
|NO JC
|
|
|
|
|--
|--
|12/6/2012
|1/3/2017
|Marilynn Chow
|Marilynn Chow
|Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression
|
|[http://openwetware.org/images/1/1d/2012_Oncogene_Pagliuca_et_al.pdf Pagliuca et al] [http://openwetware.org/images/3/3f/2012_Oncogene_Pagliuca_et_al_Supp.pdf supplement]
|
|--
|--
|1/10/2013
|1/10/2017
|Lilli Welch
|Ben Doron
|
|
|--
|1/17/2017
|Canceled
|
|
|
|
|--
|--
|1/17/2013
|1/24/2017
|Spencer Watson
|Xiaoming Ouyang
|Mitochondrial dynamics regulates migration and invasion of breast cancer cells
|
|[http://openwetware.org/images/4/4b/Onc2012494a.pdf]
|  
|--
|--
|1/24/2013
|1/31/2017
|Ping Wang
|Yingxiao Chen
|Oncogenic Kras-Induced GM-CSF Projection Promotes the Development of Pancreatic Neoplasia
|
|[http://www.ncbi.nlm.nih.gov/pubmed/22698407] [http://www.ncbi.nlm.nih.gov/pubmed/22698406]
|
|--
|--
|1/31/2013
|2/07/2017
|Aaron Wortham
|Kevin Watanabe-Smith
|Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration
|
|[http://openwetware.org/images/5/51/Luga_V_et_al_Cell_2012.pdf Luga V et al Cell 151, 1542-1556 (2012)]
|
|--
|--
|2/7/2013
|2/14/2017
|Jeff Wu
|Krishna Chauhan
|MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrinsubunits
|
| [http://www.nature.com/ncb/journal/v14/n6/pdf/ncb2491.pdf]
|
|--
|--
|2/14/2013
|2/21/2017
|Tiffany Devine
|
|The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic Sites
|
|[http://openwetware.org/images/3/3c/Gao_Cell_2012_BMP_inhibitor_coco_reactivates_BCC_at_lung_met_sites.pdf]
|
|--
|--
|2/21/2013
|2/28/2017
|Ellie Juarez
|Tyler Risom
|Poly(beta-aminoester) nanoparticle-delivery of p53 has activity against small cell lung cancer in vitro and in vivo Molecular Cancer Therapeutics
|
|[http://openwetware.org/images/b/bd/Gene_Therapy_JC_and_class.pdf]
|
|--
|--
|2/28/2013
|3/07/2017
|Tim Butler
|Lilli Klug
|tumor heterogeneity, focusing mostly on a recent science paper (Kreso 2013) which shows serially passages clones responding differently to chemotherapy
|
|[http://openwetware.org/images/0/09/Science-2013-Kreso-543-8.pdf Kreso 2013][http://openwetware.org/images/2/25/Gerlinger_2012%2C_Intratumor_Heterogeneity_multiregion_sequencing.pdf Gerlinger 2012]
|
|--
|--
|3/7/2013
|3/14/2017
|Toni West
|Xiaoming Ouyang
|Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
|
|[http://openwetware.org/images/c/c3/Schwitalla_S_et_al_Cell_152%2C_25-38_%282013%29.pdf Schwitalla S et al Cell 152, 25-38 (2013)]
|
|--
|--
|3/14/2013
|3/21/2017
|Jared Fischer
|Canceled, spring break
|Intestinal label-retaining cells are secretory precursors expressing Lgr5
|
|[http://openwetware.org/images/0/09/Nature11965%281%29.pdf]
|
|--
|--
|3/21/2013
|3/28/2017
|Mushui Dai
|David Edwards
|Splicing-Factor Oncoprotein SRSF1 Stabilizes p53 via RPL5 and Induces Cellular Senescence.
|
|[http://openwetware.org/images/5/57/2013_SRSF1_L5_p53_MC.pdf]
|
|--
|--
|4/4/2013
|4/4/2017
|Nathalie Javidi-Sharifi
|
|Tumor Stem Cells Generate Vasculature
|
|[http://openwetware.org/images/2/25/Gsc_vasculature_hutchinson_comment_nature_2011.pdf] [http://openwetware.org/images/1/17/Gsc_pericytes_cheng_cell_2013_incl_supp.pdf]
|
|--
|--
|4/11/2013
|4/11/2017
|Amy Farrell
|Chelsea Jenkins
|Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer
|
|[http://www.sciencedirect.com/science/article/pii/S1535610813000433 Stefan Eser, et al]
|
|--
|--
|4/18/2013
|4/18/2017
|Trevor Levin
|
|DNA damage foci formation around double strand breaks and regulation of NHEJ and HR repair mechanisms
|
|[http://openwetware.org/images/5/59/Zimmermann2013_53BP1_Rif1_DSBRepair.pdf Zimmerman][http://openwetware.org/images/b/ba/Virgilio2013_Rif1_DNA_Breaks_IG_Switching.pdf Virgilio][http://openwetware.org/images/7/72/Kukas2013_Rif1_Perspective.pdf Kukas]
|
|--
|--
|4/25/2013
|4/25/2017
|Kevin Watanabe-Smith
|
|"Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models"
|
|[http://openwetware.org/images/5/56/Corcoran_2013_Synthetic_Lethality_in_KRAS_mutant_cancer.pdf] [http://openwetware.org/images/6/68/Supplemental_-_Corcoran_2013.pdf]
|
|--
|--
|5/2/2013
|5/2/2017
|Stacey Lin
|Canceled---research week
|Hijacking the Neuronal NMDAR Signaling Circuit to Promote Tumor Growth and Invasion
|
|[http://openwetware.org/images/a/ac/Li_and_Hanahan.pdf]
|--
|--
|5/9/2013
|5/9/2017
|Juan Liang
|Ben Doron
|Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53
|
|[http://openwetware.org/images/0/0e/2012_Cance_Cell_Inhibition_of_RNA_Polymerase_I_as_a_Therapeutic_Strategy.pdf]
|
|--
|--
|5/16/201
|5/16/2017
|Xiaoxin Sun
|
|Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP
|
|[http://openwetware.org/images/5/5f/Cancer_journal_club_paper.pdf]
|
|--
|--
|5/23/2013
|5/23/2017
|Dr. Charles Lopez
|
|CANCELED DUE TO RESEARCH WEEK
|
|
|
|--
|--
|5/30/2013
|5/30/2017
|Mahnaz Janghorban
|Tyler Risom
|Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer
|
|[http://openwetware.org/images/b/b2/Loss_of_FBP1_by_Snail-Mediated_Repression_Provides_Metabolic_Advantages_in_Basal-like_Breast_Cancer.pdf Dong et al]
|
|--
|--
|6/6/2013
|6/06/2016
|Marcus Calkins
|
|The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation
|
|
|}
|}
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Revision as of 21:39, 16 January 2017

Equipped with his five senses, man explores the universe around him and calls the adventure Science. ~Edwin Powell Hubble, The Nature of Science, 1954

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Objectives of the OHSU Cancer Biology Journal Club

Cross-departmental journal club composed of students, postdocs, fellows and clinical and basic science faculty with shared interest in basic principles, emerging discoveries, and new therapeutic approaches in Cancer Biology. The goals of the meetings are to:

  • Critically evaluate new cutting edge literature on mechanisms underlying the development and maintenance of cancer to inform the development of new therapeutics. Papers should be paradigm shifting and set a backdrop for discussion into therapeutics facilitated by the clinical attendees.
  • Provide students, postdocs and fellows with training and interactions with faculty interested in Cancer Biology and emerging therapeutics

KCI CJC Information

Want to join us? All are invited!

  • To get on the listserve:
go to the following web site:
http://mailman.ohsu.edu/cgi-bin/mailman/listinfo/oncobio
follow instructions for subscribing
  • To send out your paper
Send an e-mail to 'oncobioATohsu.edu' with your paper attached
  • When and where we meet
MacHall 2136
Tuesdays noon-1 PM
Lunch provided by KCI
  • Organizer contact information:
Mushui Dai-daim@ohsu.edu
David Qian-qianzh@ohsu.edu
Charlie Lopez- lopezc@ohsu.edu

Member Labs and Affiliations

Lopez Lab Hem Onc

Sears Lab

Hoatlin Lab

Thayer Lab

Wong Lab

Lloyd Lab CROET

McCullough Lab CROET

Schedule

  • Scheduling In Progress
Date Presenters Topic Links & Comments
09/27/2016 Organization
10/4/2016 Kevin Watanabe-Smith
10/11/2016 Timothy Carey
10/18/2016 Xiao-Xin Sun
10/25/2016 Lilli Klug
11/1/2016 Marilynn Chow
11/8/2016 Sherif Abdelhamed
11/15/2016 Chelsea Jenkins
11/22/2016 Ben Doron
11/29/2016 David Edwards
12/06/2016 Cymon Kirsh
12/13/2016 NO JC
12/20/2016 NO JC
12/27/2016 NO JC
1/3/2017 Marilynn Chow
1/10/2017 Ben Doron
1/17/2017 Canceled
1/24/2017 Xiaoming Ouyang
1/31/2017 Yingxiao Chen
2/07/2017 Kevin Watanabe-Smith
2/14/2017 Krishna Chauhan
2/21/2017
2/28/2017 Tyler Risom
3/07/2017 Lilli Klug
3/14/2017 Xiaoming Ouyang
3/21/2017 Canceled, spring break
3/28/2017 David Edwards
4/4/2017
4/11/2017 Chelsea Jenkins
4/18/2017
4/25/2017
5/2/2017 Canceled---research week
5/9/2017 Ben Doron
5/16/2017
5/23/2017
5/30/2017 Tyler Risom
6/06/2016
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