Lee:JC: Difference between revisions
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== | ==Lab meeting schedule== | ||
* | * 9:30 am, 수요일 | ||
{| border="1" | {| border="1" | ||
|+ | |+ | ||
|width=' | |width='150'|'''Date''' | ||
|width=' | |width='300'|'''Presenter/discussion leader''' | ||
|- | |- | ||
| | |5/30/17 || Research | ||
|- | |- | ||
| | |6/13/17 || JC (예린) | ||
|- | |- | ||
| | |6/28/17 || Research (지은, 예린) | ||
|- | |- | ||
|7/ | |7/5/17 || JC (지수/나은) | ||
|- | |- | ||
| | |7/12/17 || Research (윤석, 공미) | ||
|- | |- | ||
| | |7/19/17 || JC (지민/근혜) | ||
|- | |- | ||
| | |7/26/17 || Research (지은, 예린) | ||
|- | |- | ||
| | |8/16/17 || JC (공미) | ||
|- | |- | ||
| | |8/23/17 || Research (윤석, 공미) | ||
|- | |- | ||
|10/22/ | |}<br> | ||
==Past papers== | |||
===2017=== | |||
# Kang T, Zhu Q, Wei D, Feng J, Yao J, Jiang T, Song Q, Wei X, Chen H, Gao X, Chen J.Nanoparticles Coated with Neutrophil Membranes Can Effectively Treat Cancer Metastasis. ACS Nano. 2017 Jan 26. doi: 10.1021/acsnano.6b06477. (PMID: 28075552) (2/14/17 JP) | |||
# Liu Q, Liu L, Zhao Y, Zhang J, Wang D, Chen J, He Y, Wu J, Zhang Z, Liu Z. Hypoxia induces genomic DNA demethylation through the activation of HIF-1α and transcriptional upregulation of MAT2A in hepatoma cells. Mol Cancer Ther. 2011 Jun;10(6):1113-23. (PMID: 21460102) (3/14/17, GM) | |||
# Morita Y, Kamal M, Kang SA, Zhang R, Lokesh GL, Thiviyanathan V, Hasan N, Woo S, Zhao D, Leslie M, Suh S, Razaq W, Rui H, Gorenstein DG, Volk DE, Tanaka T. E-selectin Targeting PEGylated-thioaptamer Prevents Breast Cancer Metastases. Mol Ther Nucleic Acids. 2016;5:e399. doi: 10.1038/mtna.2016.103. (PMID: 28131283) (3/28/17, YR) | |||
# Hutt DM, Roth DM, Vignaud H, Cullin C, Bouchecareilh M. The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition. PLoS One. 2014 Aug 28;9(8):e106224. doi: 10.1371/journal.pone.0106224. eCollection 2014. (PMID: 25166596) (4/18/17, GM) | |||
# V. Tong, F.S. Abbott, S. Mbofana, M.J. Walker, In vitro investigation of the hepatic extraction of RSD1070, a novel antiarrhythmic compound, J Pharm Pharm Sci 4(1) (2001) 15-23 (PMID: 11302786) (5/10/17, YO) | |||
# J. Schafer, L. Welti, A. Seckinger, J. Burhenne, D. Theile, J. Weiss, Cellular effect and efficacy of carfilzomib depends on cellular net concentration gradient, Cancer Chemother Pharmacol (2017) (PMID: 28500557) (5/23/17, JP). | |||
===2016=== | |||
# Reiner T, Parrondo R, de Las Pozas A, Palenzuela D, Perez-Stable C. Betulinic acid selectively increases protein degradation and enhances prostate cancer-specific apoptosis: possible role for inhibition of deubiquitinase activity. PLoS One. 2013;8(2):e56234. doi: 10.1371/journal.pone.0056234. (1/12/16, 지은) | |||
# Ramachandran A, Betts G, Bhana S, Helme G, Blick C, Moller-Levet C, Saunders E, Valentine H, Pepper S, Miller CJ, Buffa F, Harris AL, West CM. An in vivo hypoxia metagene identifies the novel hypoxia inducible factor target gene SLCO1B3. Eur J Cancer. 2013 May;49(7):1741-51. doi: 10.1016/j.ejca.2012.12.003. PMID: 23352438 (2/22/16, 송희) | |||
# Chan T, Cheung FS, Zheng J, Lu X, Zhu L, Grewal T, Murray M, Zhou F. Casein kinase 2 is a novel regulator of the human organic anion transporting polypeptide 1A2 (OATP1A2) trafficking. Mol Pharm. 2016 Jan 4;13(1):144-54. doi: 10.1021/acs.molpharmaceut.5b00576. PMID: 26580496 (3/15/16, 세은) | |||
# He X, Wang J, Wei W, Shi M, Xin B, Zhang T, Shen X. Hypoxia regulates ABCG2 activity through the activivation of ERK1/2/HIF-1α and contributes to chemoresistance in pancreatic cancer cells. Cancer Biol Ther. 2016 Jan 19:1-11. PMID: 26785721 (3/29/16, 윤석) | |||
# Sato H, Macchiarulo A, Thomas C, Gioiello A, Une M, Hofmann AF, Saladin R, Schoonjans K, Pellicciari R, Auwerx J. Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies. J Med Chem. 2008 Mar 27;51(6):1831-41. PMID: 18307294 (4/19/16, 공미) | |||
# Morgan JA, Lynch J, Panetta JC, Wang Y, Frase S, Bao J, Zheng J, Opferman JT, Janke L, Green DM, Chemaitilly W, Schuetz JD. Apoptosome activation, an important molecular instigator in 6-mercaptopurine induced Leydig cell death. Sci Rep. 2015 Nov 18;5:16488. PMID: 26576726 (5/16/16, 지은) | |||
# Krishnamurthy P, Ross DD, Nakanishi T, Bailey-Dell K, Zhou S, Mercer KE, Sarkadi B, Sorrentino BP, Schuetz JD. The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. J Biol Chem. 2004 Jun 4;279(23):24218-25. PMID: 15044468 (5/27/16, 송희) | |||
# Bakos E, Evers R, Calenda G, Tusnády GE, Szakács G, Váradi A, Sarkadi B. Characterization of the amino-terminal regions in the human multidrug resistance protein (MRP1). J Cell Sci. 2000 Dec;113 Pt 24:4451-61. PMID: 11082039 (6/28/16, 세은) | |||
# Wang X, Tang Y, Lu J, Shao Y, Qin X, Li Y, Wang L, Li D, Liu M. Characterization of novel cytochrome P450 2E1 knockout rat model generated by CRISPR/Cas9. Biochem Pharmacol. 2016 Apr 1;105:80-90. PMID: 26947455 (7/12/16, 민경) | |||
# Deng R, Bumbaca D, Pastuskovas CV, Boswell CA, West D, Cowan KJ, Chiu H, McBride J, Johnson C, Xin Y, Koeppen H, Leabman M, Iyer S. Preclinical pharmacokinetics, pharmacodynamics, tissue distribution, and tumor penetration of anti-PD-L1 monoclonal antibody, an immune checkpoint inhibitor. MAbs. 2016 Apr;8(3):593-603. PMID: 26918260 (7/27/16, 연희) | |||
# To KK, Leung WW, Ng SS. A novel miR-203-DNMT3b-ABCG2 regulatory pathway predisposing colorectal cancer development. Mol Carcinog. 2016 Jun 2. PMID: 27253631 (8/9/16, 윤석) | |||
# Wang YD, Chen WD, Yu D, Forman BM, Huang W. The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor κ light-chain enhancer of activated B cells (NF-κB) in mice. Hepatology. 2011 Oct;54(4):1421-32. PMID: 21735468 (9/23/16, 공미) | |||
# Petrocca F, Altschuler G, Tan SM, Mendillo ML, Yan H, Jerry DJ, Kung AL, Hide W, Ince TA, Lieberman J. A genome-wide siRNA screen identifies proteasome addiction as a vulnerability of basal-like triple-negative breast cancer cells. Cancer Cell. 2013 Aug 12;24(2):182-96. PMID: 23948298 (10/11/16, 지은) | |||
# Kasai T, Nakanishi T, Ohno Y, Shimada H, Nakamura Y, Arakawa H, Tamai I. Role of OATP2A1 in PGE2 secretion from human colorectal cancer cells via exocytosis in response to oxidative stress. Exp Cell Res. 2016 Feb 15;341(2):123-31. PMID: 26850138 (11/1/16, 세은) | |||
== | ===2015=== | ||
# Errasti-Murugarren E, Casado FJ, Pastor-Anglada M. Different N-terminal motifs determine plasma membrane targeting of the human concentrative nucleoside transporter 3 in polarized and nonpolarized cells. Mol Pharmacol. 2010 Nov;78(5):795-803. doi: 10.1124/mol.110.065920. PMID: 20643903 (7/5/15, 세은) | |||
# Imai S, Kikuchi R, Tsuruya Y, Naoi S, Nishida S, Kusuhara H, Sugiyama Y. Epigenetic regulation of organic anion transporting polypeptide 1B3 in cancer cell lines. Pharm Res. 2013 Nov;30(11):2880-90. doi: 10.1007/s11095-013-1117-1. PMID: 23812637 (7/22/15, 윤석) | |||
# Arakawa H, Nakanishi T, Yanagihara C, Nishimoto T, Wakayama T, Mizokami A, Namiki M, Kawai K, Tamai I. Enhanced expression of organic anion transporting polypeptides (OATPs) in androgen receptor-positive prostate cancer cells: possible role of OATP1A2 in adaptive cell growth under androgen-depleted conditions. Biochem Pharmacol. 2012 Oct 15;84(8):1070-7. doi: 10.1016/j.bcp.2012.07.026. PMID: 22864060 (8/5/15, 진아) | |||
# Yang J, Wang Z, Fang Y, Jiang J, Zhao F, Wong H, Bennett MK, Molineaux CJ, Kirk CJ. Pharmacokinetics, pharmacodynamics, metabolism, distribution, and excretion of carfilzomib in rats. Drug Metab Dispos. 2011 Oct;39(10):1873-82. doi: 10.1124/dmd.111.039164. PMID: 21752943 (9/3/15, 지은) | |||
# Schaffner CA, Mwinyi J, Gai Z, Thasler WE, Eloranta JJ, Kullak-Ublick GA. The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes. Liver Int. 2015 Apr;35(4):1152-61. doi: 10.1111/liv.12558. PMID: 24703425 (9/18/15, 윤석) | |||
# Kim D, Ko P, You E, Rhee S. The intracellular juxtamembrane domain of discoidin domain receptor 2 (DDR2) is essential for receptor activation and DDR2-mediated cancer progression. Int J Cancer. 2014 Dec 1;135(11):2547-57. doi: 10.1002/ijc.28901. PMID: 24740739 (10/12/15, 송희) | |||
# Hong M, Hong W, Ni C, Huang J, Zhou C.Protein kinase C affects the internalization and recycling of organic anion transporting polypeptide 1B1. Biochim Biophys Acta. 2015;1848(10 Pt A):2022-30. doi: 10.1016/j.bbamem.2015.05.011. (10/26/15, 세은) | |||
# Shen S, Du XJ, Liu J, Sun R, Zhu YH, Wang J. Delivery of bortezomib with nanoparticles for basal-like triple-negative breast cancer therapy. J Control Release. 2015 Jun 28;208:14-24. doi: 10.1016/j.jconrel.2014.12.043. (11/23/15, 지은) | |||
# Heink S, Fricke B, Ludwig D, Kloetzel PM, Krüger E. Tumor cell lines expressing the proteasome subunit isoform LMP7E1 exhibit immunoproteasome deficiency. Cancer Res. 2006 Jan 15;66(2):649-52. PMID: 16423992 (12/7/15, 송희) | |||
# Hong W, Wu Z, Fang Z, Huang J, Huang H, Hong M. Amino Acid Residues in the Putative Transmembrane Domain 11 of Human Organic Anion Transporting Polypeptide 1B1 Dictate Transporter Substrate Binding, Stability, and Trafficking. Mol Pharm. 2015 Dec 7;12(12):4270-6. doi: 10.1021/acs.molpharmaceut.5b00466. (12/21/15, 세은) | |||
===2014=== | |||
# Stessman HA, Mansoor A, Zhan F, Linden MA, Van Ness B, Baughn LB. Bortezomib resistance can be reversed by induced expression of plasma cell maturation markers in a mouse in vitro model of multiple myeloma. PLoS One. 2013 Oct 29;8(10):e77608. doi: 10.1371/journal.pone.0077608. (1/16/14 JEP) | |||
# Subramanian VS, Marchant JS, Said HM. Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia. Am J Physiol Cell Physiol. 2008 Jan;294(1):C233-40. (2/13/14, NT) | |||
# Fabre B1, Lambour T, Delobel J, Amalric F, Monsarrat B, Burlet-Schiltz O, Bousquet-Dubouch MP. Subcellular distribution and dynamics of active proteasome complexes unraveled by a workflow combining in vivo complex cross-linking and quantitative proteomics. Mol Cell Proteomics. 2013 Mar;12(3):687-99. (2/17/14, KCC) | |||
# Niewerth D, Kaspers GJ, Assaraf YG, van Meerloo J, Kirk CJ, Anderl J, Blank JL, van de Ven PM, Zweegman S, Jansen G, Cloos J. Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines. J Hematol Oncol. 2014 Jan 13;7(1):7. (3/13/14, MJL) | |||
# Pack CG, Yukii H, Toh-e A, Kudo T, Tsuchiya H, Kaiho A, Sakata E, Murata S, Yokosawa H, Sako Y, Baumeister W, Tanaka K, Saeki Y. Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome. Nat Commun. 2014 Mar 6;5:3396. doi: 10.1038/ncomms4396.(PMID: 24598877) (3/27/14, LA) | |||
# Raule M, Cerruti F, Benaroudj N, Migotti R, Kikuchi J, Bachi A, Navon A, Dittmar G, Cascio P. PA28αβ Reduces Size and Increases Hydrophilicity of 20S Immunoproteasome Peptide Products. Chem Biol. 2014 Apr 24;21(4):470-80. doi: 10.1016/j.chembiol.2014.02.006. Epub 2014 Mar 13. (PMID: 24631123) (4/17/14, ZM) | |||
# Ali A, Wang Z, Fu J, Ji L, Liu J, Li L, Wang H, Chen J, Caulin C, Myers JN, Zhang P, Xiao J, Zhang B, Li X. Differential regulation of the REGγ-proteasome pathway by p53/TGF-β signalling and mutant p53 in cancer cells. Nat Commun. 2013;4:2667. doi: 10.1038/ncomms3667. (PMID: 24157709) (5/1/14, KCC) | |||
# Crawford LJ, Chan ET, Aujay M, Holyoake TL, Melo JV, Jorgensen HG, Suresh S, Walker B, Irvine AE. Synergistic effects of proteasome inhibitor carfilzomib in combination with tyrosine kinase inhibitors in imatinib-sensitive and -resistant chronic myeloid leukemia models. Oncogenesis. 2014 (PMID: 24590311) (6/5/14, MJL) | |||
# Wang P1, Wang JJ, Xiao Y, Murray JW, Novikoff PM, Angeletti RH, Orr GA, Lan D, Silver DL, Wolkoff AW. Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface. J Biol Chem. 2005 Aug 26;280(34):30143-9. (6/19/14, NT) | |||
# Swami A, Reagan MR, Basto P, Mishima Y, Kamaly N, Glavey S, Zhang S, Moschetta M, Seevaratnam D, Zhang Y, Liu J, Memarzadeh M, Wu J, Manier S, Shi J, Bertrand N, Lu ZN, Nagano K, Baron R, Sacco A, Roccaro AM, Farokhzad OC, Ghobrial IM. Engineered nanomedicine for myeloma and bone microenvironment targeting. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10287-92. (7/10/14, LA) | |||
# Gohlke S, Kloss A, Tsokos M, Textoris-Taube K, Keller C, Kloetzel PM, Dahlmann B. Adult human liver contains intermediate-type proteasomes with different enzymatic properties. Ann Hepatol. 2014 Jul-Aug;13(4):429-38. (7/24/14, JP) | |||
# Krönke J, Udeshi ND, Narla A, Grauman P, Hurst SN, McConkey M, Svinkina T, Heckl D, Comer E, Li X, Ciarlo C, Hartman E, Munshi N, Schenone M, Schreiber SL, Carr SA, Ebert BL. Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells. Science. 2014 Jan 17;343(6168):301-5. (8/07/14, KCC) | |||
# Liu Z, Chen P, Gao H, Gu Y, Yang J, Peng H, Xu X, Wang H, Yang M, Liu X, Fan L, Chen S, Zhou J, Sun Y, Ruan K, Cheng S, Komatsu M, White E, Li L, Ji H, Finley D, Hu R. Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppression. Cancer Cell. 2014 Jul 14;26(1):106-20. doi: 10.1016/j.ccr.2014.05.015. PMID: 25026213 (9/5/14 MJL) | |||
# Minoia M, Boncoraglio A, Vinet J, Morelli FF, Brunsting JF, Poletti A, Krom S, Reits E, Kampinga HH, Carra S. BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: Implications for a proteasome-to-autophagy switch. Autophagy. 2014 Sep 1;10(9):1603-21. doi: 10.4161/auto.29409. Epub 2014 Jul 10. PMID: 25046115 (9/19/14, LA) | |||
# Yu T, Tao Y, Yang M, Chen P, Gao X, Zhang Y, Zhang T, Chen Z, Hou J, Zhang Y, Ruan K, Wang H, Hu R. Profiling human protein degradome delineates cellular responses to proteasomal inhibition and reveals a feedback mechanism in regulating proteasome homeostasis. Cell Res. 2014 Oct;24(10):1214-30. doi: 10.1038/cr.2014.122. Epub 2014 Sep 16. PMID: 25223703 (10/10/14, JP) | |||
== | ===2013=== | ||
# | # Pinilla-Macua I, Casado FJ, Pastor-Anglada M. Structural determinants for rCNT2 sorting to the plasma membrane of polarized and non-polarized cells. Biochem J. 2012 Mar 15;442(3):517-25. doi: 10.1042/BJ20110605. (1/7/13 NT) | ||
# | # Day E, Waters B, Spiegel K, Alnadaf T, Manley PW, Buchdunger E, Walker C, Jarai G. Inhibition of collagen-induced discoidin domain receptor 1 and 2 activation by imatinib, nilotinib and dasatinib.Eur J Pharmacol. 2008 Dec 3;599(1-3):44-53 (2/4/13 YRL) | ||
# Roué G, Pérez-Galán P, Mozos A, López-Guerra M, Xargay-Torrent S, Rosich L, Saborit-Villarroya I, Normant E, Campo E, Colomer D. The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78. Blood. 2011 Jan 27;117(4):1270-9. Epub 2010 Nov 24. | # Ramachandran A, Betts G, Bhana S, Helme G, Blick C, Moller-Levet C, Saunders E, Valentine H, Pepper S, Miller CJ, Buffa F, Harris AL, West CM. An in vivo hypoxia metagene identifies the novel hypoxia inducible factor target gene SLCO1B3. Eur J Cancer. 2013 Jan 23. doi:pii: S0959-8049(12)00960-4. 10.1016/j.ejca.2012.12.003 (2/18/13, KBK) | ||
# | # Maldonado M, Kapphahn RJ, MR Terluk, ND Heuss, C Yuan, DS Gregerson, DA Ferrington. Immunoproteasome Deficiency Modifies the Alternative Pathway of NFκB Signaling. Plos One 2013 (3/4/13, LA) | ||
# | # Ali BR, Xu H, Akawi NA, John A, Karuvantevida NS, Langer R, Al-Gazali L, Leitinger B. Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients.Hum Mol Genet. 2010 Jun 1;19(11):2239-50. doi: 10.1093/hmg/ddq103. Epub 2010 Mar 10. (3/18/13, YRL) | ||
# | # Knauer MJ, Girdwood AJ, Kim RB, Tirona RG. Transport Function and Transcriptional Regulation of a Liver-Enriched Human Organic Anion Transporting Polypeptide 2B1 Transcriptional Start Site Variant. Mol Pharmacol. 2013 Mar 26 (4/15/13, NT) | ||
# | # Roué G, Pérez-Galán P, Mozos A, López-Guerra M, Xargay-Torrent S, Rosich L, Saborit-Villarroya I, Normant E, Campo E, Colomer D. The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78. Blood. 2011 Jan 27;117(4):1270-9. doi: 10.1182/blood-2010-04-278853. Epub 2010 Nov 24. (4/29/13, LA) | ||
# | # Zhang K, Corsa CA, Ponik SM, Prior JL, Piwnica-Worms D, Eliceiri KW, Keely PJ, Longmore GD. The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis.Nat Cell Biol. 2013 May 5. doi: 10.1038/ncb2743. (5/13/13, W) | ||
# | # Carafoli F, Mayer MC, Shiraishi K, Pecheva MA, Chan LY, Nan R, Leitinger B, Hohenester E. Structure of the discoidin domain receptor 1 extracellular region bound to an inhibitory Fab fragment reveals features important for signaling.Structure. 2012 Apr 4;20(4):688-97. doi: 10.1016/j.str.2012.02.011. (6/10/13, YRL) | ||
# | # Sun AQ, Salkar R, Sachchidanand, Xu S, Zeng L, Zhou MM, Suchy FJ. A 14-amino acid sequence with a beta-turn structure is required for apical membrane sorting of the rat ileal bile acid transporter. J Biol Chem. 2003 Feb 7;278(6):4000-9. (6/24/13, NT) | ||
# Gohlke S, Mishto M, Textoris-Taube K, Keller C, Giannini C, Vasuri F, Capizzi E, D'Errico-Grigioni A, Kloetzel PM, Dahlmann B.Molecular alterations in proteasomes of rat liver during aging result in altered proteolytic activities. Age (Dordr). 2013 May 22. [Epub ahead of print] PMID:23690132 (7/1/13, YW) | |||
# Nathan JA, Spinnenhirn V, Schmidtke G, Basler M, Groettrup M, Goldberg AL. Immuno- and constitutive proteasomes do not differ in their abilities to degrade ubiquitinated proteins. Cell. 2013 Feb 28;152(5):1184-94 (7/15/13, KC) | |||
# Lőw P, Varga A, Pircs K, Nagy P, Szatmári Z, Sass M, Juhász G. Impaired proteasomal degradation enhances autophagy via hypoxia signaling in Drosophila. BMC Cell Biol. 2013 Jun 25;14(1):29. doi: 10.1186/1471-2121-14-29. (PMID: 23800266)(8/12/13, DL) | |||
# Zhu K, Dunner K Jr, McConkey DJ. Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells. Oncogene. 2010 Jan 21;29(3):451-62. doi: 10.1038/onc.2009.343. (8/26/13, LA) | |||
# Chou TF, Li K, Frankowski KJ, Schoenen FJ, Deshaies RJ.Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase. ChemMedChem. 2013 Feb;8(2):297-312. (9/9/13, ZM) | |||
# Leung-Hagesteijn C, Erdmann N, Cheung G, Keats JJ, Stewart AK, Reece DE, Chung KC, Tiedemann RE. Xbp1s-negative tumor B cells and pre-plasmablasts mediate therapeutic proteasome inhibitor resistance in multiple myeloma. Cancer Cell. 2013 Sep 9;24(3):289-304. (9/23/13, JP) | |||
# Zhang Q, Suh W, Pan Z, You G. Short-term and long-term effects of protein kinase C on the trafficking and stability of human organic anion transporter 3. Int J Biochem Mol Biol. 2012;3(2):242-9. (10/8/13 NT) | |||
# Niewerth D, Franke NE, Jansen G, Assaraf YG, van Meerloo J, Kirk C, Degenhardt J, Anderl J, Schimmer AD, Zweegman S, de Haas V, Horton TM, Kaspers GJ, Cloos J. Higher ratio immune vs. constitutive proteasome level as novelindicator of sensitivity of pediatric acute leukemia cells to proteasomeinhibitors. Haematologica. 2013 Sep 20. PMID:24056819 (10/22/13, KC) | |||
# Zhang L, Pham LV, Newberry KJ, Ou Z, Liang R, Qian J, Sun L, Blonska M, You Y, Yang J, Lin X, Rollo A, Tamayo AT, Lee J, Ford RJ, Zhao X, Kwak LW, Yi Q, Wang M.In Vitro and In Vivo Therapeutic Efficacy of Carfilzomib in Mantle Cell Lymphoma: Targeting the Immunoproteasome. Mol Cancer Ther. 2013 Oct 29. (11/5/13, DH) | |||
# Fan F, Tonon G, Bashari MH, Vallet S, Antonini E, Goldschmidt H, Schulze-Bergkamen H, Opferman JT, Sattler M, Anderson KC, Jäger D, Podar K. Targeting Mcl-1 for multiple myeloma (MM) therapy: Drug-induced generation of Mcl-1 fragment Mcl-1<sup>128-350</sup> triggers MM cell death via c-Jun upregulation. Cancer Lett. 2013 Oct 8. doi:pii: S0304-3835(13)00712-X. 10.1016/j.canlet.2013.09.042. (PMID:24120758) (11/19/13, MJL) | |||
# Hasegawa M, Yasuda Y, Tanaka M, Nakata K, Umeda E, Wang Y, Watanabe C, Uetake S, Kunoh T, Shionyu M, Sasaki R, Shiina I, Mizukami T. A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor. Eur J Med Chem. 2013 Nov 16;71C:290-305. doi: 10.1016/j.ejmech.2013.11.009. (12/3/13, ZM) | |||
# Suraweera A, Münch C, Hanssum A, Bertolotti A. Failure of amino acid homeostasis causes cell death following proteasome inhibition. Mol Cell. 2012 Oct 26;48(2):242-53. doi: 10.1016/j.molcel.2012.08.003. (12/17/13, LA) | |||
===2012=== | ===2012=== | ||
# Fang C, Dean J, Smith JW. A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma. Cancer Res. 2007 Oct 1;67(19):9039-46. (pmid=17909007) (1/17/12 SH) | # Fang C, Dean J, Smith JW. A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma. Cancer Res. 2007 Oct 1;67(19):9039-46. (pmid=17909007) (1/17/12 SH) | ||
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# Degorter MK, Ho RH, Leake BF, Tirona RG, Kim RB. Interaction of three regiospecific amino acid residues is required for OATP1B1 gain of OATP1B3 substrate specificity. Mol Pharm. 2012 Apr 2;9(4):986-95. Epub 2012 Mar 6. (PMID: 22352740) (5/33/12, NT) | # Degorter MK, Ho RH, Leake BF, Tirona RG, Kim RB. Interaction of three regiospecific amino acid residues is required for OATP1B1 gain of OATP1B3 substrate specificity. Mol Pharm. 2012 Apr 2;9(4):986-95. Epub 2012 Mar 6. (PMID: 22352740) (5/33/12, NT) | ||
# Fellerhoff B, Gu S, Laumbacher B, Nerlich AG, Weiss EH, Glas J, Kopp R, Johnson JP, Wank R. The LMP7-K allele of the immunoproteasome exhibits reduced transcript stability and predicts high risk of colon cancer. Cancer Res. 2011 Dec 1;71(23):7145-54. Epub 2011 Oct 28. (PMID: 22037870) (6/5/12, JP) | # Fellerhoff B, Gu S, Laumbacher B, Nerlich AG, Weiss EH, Glas J, Kopp R, Johnson JP, Wank R. The LMP7-K allele of the immunoproteasome exhibits reduced transcript stability and predicts high risk of colon cancer. Cancer Res. 2011 Dec 1;71(23):7145-54. Epub 2011 Oct 28. (PMID: 22037870) (6/5/12, JP) | ||
# Errasti-Murugarren E, Molina-Arcas M, Casado FJ, Pastor-Anglada M. A splice variant of the SLC28A3 gene encodes a novel human concentrative nucleoside transporter-3 (hCNT3) protein localized in the endoplasmic reticulum. FASEB J. 2009 Jan;23(1):172-82. (PMID=18827020) (6/19/12, KBj) | |||
# Wang Z, Sun Y. Identification and characterization of two splicing variants of human Noxa. Anticancer Res. 2008 May-Jun;28(3A):1667-74. (PMID=18630524) (7/2/12, YL) | |||
# Higashimura Y, Nakajima Y, Yamaji R, Harada N, Shibasaki F, Nakano Y, Inui H. Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells. Arch Biochem Biophys. 2011 May 1;509(1):1-8. (PMID=21338575) (7/31/12 SHH) | |||
# Errasti-Murugarren E, Casado FJ, Pastor-Anglada M. Different N-terminal motifs determine plasma membrane targeting of the human concentrative nucleoside transporter 3 in polarized and nonpolarized cells. Mol Pharmacol. 2010 Nov;78(5):795-803. (PMID=20643903 8/14/12 NT) | |||
# Hammerman PS et al. Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. Cancer Discov. 2011 Jun;1(1):78-89. (PMID=22328973, 8/28/12 YRL) | |||
# Heink S, Ludwig D, Kloetzel PM, Krüger E. IFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient response. Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9241-6. (PMID: 15944226 9/10/12 KBj) | |||
# Blackburn C, Gigstad KM, Hales P, Garcia K, Jones M, Bruzzese FJ, Barrett C, Liu JX, Soucy TA, Sappal DS, Bump N, Olhava EJ, Fleming P, Dick LR, Tsu C, Sintchak MD, Blank JL. Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit. Biochem J. 2010 Sep 15;430(3):461-76. (9/24/12 JP) | |||
# Joeris T, Schmidt N, Ermert D, Krienke P, Visekruna A, Kuckelkorn U, Kaufmann SH, Steinhoff U. The proteasome system in infection: impact of β5 and LMP7 on composition, maturation and quantity of active proteasome complexes. PLoS One. 2012;7(6):e39827. (10/9/12 LA) | |||
# Tainton KM, Smyth MJ, Jackson JT, Tanner JE, Cerruti L, Jane SM, Darcy PK, Johnstone RW.Mutational analysis of P-glycoprotein: suppression of caspase activation in the absence of ATP-dependent drug efflux. Cell Death Differ. 2004 Sep;11(9):1028-37. PMID: 15131592 (10/22/12 NT) | |||
# Yang K, Kim JH, Kim HJ, Park IS, Kim IY, Yang BS. Tyrosine 740 phosphorylation of discoidin domain receptor 2 by Src stimulates intramolecular autophosphorylation and Shc signaling complex formation. J Biol Chem. 2005 Nov 25;280(47):39058-66. (11/5/12 YRL) | |||
# Mishto M, Santoro A, Bellavista E, Sessions R, Textoris-Taube K, Dal Piaz F, Carrard G, Forti K, Salvioli S, Friguet B, Kloetzel PM, Rivett AJ, Franceschi C. A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms. Biol Chem. 2006 Apr;387(4):417-29. (PMID:16606340) (11/19/12 JP) | |||
# Mizukami Y, Fujiki K, Duerr EM, Gala M, Jo WS, Zhang X, Chung DC. Hypoxic regulation of vascular endothelial growth factor through the induction of phosphatidylinositol 3-kinase/Rho/ROCK and c-Myc. J Biol Chem. 2006;281(20):13957-63. (12/3/12, KBj) | |||
# Lansdell TA, Hurchla MA, Xiang J, Hovde S, Weilbaecher KN, Henry RW, Tepe JJ. Noncompetitive Modulation of the Proteasome by Imidazoline Scaffolds Overcomes Bortezomib Resistance and Delays MM Tumor Growth in Vivo. ACS Chem Biol. 2012 Dec 11. (12/17/11, LA) | |||
===2011=== | ===2011=== | ||
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# Taub ME, Mease K, Sane RS, Watson CA, Chen L, Ellens H, Hirakawa B, Reyner EL, Jani M, Lee CA. Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells. Drug Metab Dispos. 2011 Nov;39(11):2093-102. Epub 2011 Aug 17. | # Taub ME, Mease K, Sane RS, Watson CA, Chen L, Ellens H, Hirakawa B, Reyner EL, Jani M, Lee CA. Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells. Drug Metab Dispos. 2011 Nov;39(11):2093-102. Epub 2011 Aug 17. | ||
===2010 | ===2010=== | ||
# Parlati F, Lee SJ, Aujay M, Suzuki E, Levitsky K, Lorens JB, Micklem DR, Ruurs P, Sylvain C, Lu Y, Shenk KD, Bennett MK. Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome. Blood. 2009 Oct 15;114(16):[http://bloodjournal.hematologylibrary.org/cgi/reprint/114/16/3439 3439-47]. (pmid=19671918) | # Parlati F, Lee SJ, Aujay M, Suzuki E, Levitsky K, Lorens JB, Micklem DR, Ruurs P, Sylvain C, Lu Y, Shenk KD, Bennett MK. Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome. Blood. 2009 Oct 15;114(16):[http://bloodjournal.hematologylibrary.org/cgi/reprint/114/16/3439 3439-47]. (pmid=19671918) | ||
# Deborah J. Kuhn,1 Sally A. Hunsucker,1 Qing Chen,2 Peter M. Voorhees,2 Marian Orlowski,3 Robert Z. Orlowski1. Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors.Blood. 2009 May 7;113(19):[http://bloodjournal.hematologylibrary.org/cgi/reprint/113/19/4667 4667-76]. (pmid=19050304) | # Deborah J. Kuhn,1 Sally A. Hunsucker,1 Qing Chen,2 Peter M. Voorhees,2 Marian Orlowski,3 Robert Z. Orlowski1. Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors.Blood. 2009 May 7;113(19):[http://bloodjournal.hematologylibrary.org/cgi/reprint/113/19/4667 4667-76]. (pmid=19050304) | ||
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# Yasuda H, Hirata S, Inoue K, Mashima H, Ohnishi H, Yoshiba M. Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells. Biochem Biophys Res Commun. 2007 Mar 2;354(1):[http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WBK-4MP5JGJ-C-9&_cdi=6713&_user=16764&_pii=S0006291X06028439&_origin=search&_coverDate=03%2F02%2F2007&_sk=996459998&view=c&wchp=dGLbVzb-zSkWb&md5=203a244a62ad6ef3293be26a9666deef&ie=/sdarticle.pdf 154-9]. (pmid=17214962) | # Yasuda H, Hirata S, Inoue K, Mashima H, Ohnishi H, Yoshiba M. Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells. Biochem Biophys Res Commun. 2007 Mar 2;354(1):[http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WBK-4MP5JGJ-C-9&_cdi=6713&_user=16764&_pii=S0006291X06028439&_origin=search&_coverDate=03%2F02%2F2007&_sk=996459998&view=c&wchp=dGLbVzb-zSkWb&md5=203a244a62ad6ef3293be26a9666deef&ie=/sdarticle.pdf 154-9]. (pmid=17214962) | ||
# Fuchs D, Berges C, Opelz G, Daniel V, Naujokat C. Increased expression and altered subunit composition of proteasomes induced by continuous proteasome inhibition establish apoptosis resistance and hyperproliferation of Burkitt lymphoma cells. J Cell Biochem. 2008 Jan 1;103(1):[http://onlinelibrary.wiley.com/doi/10.1002/jcb.21405/pdf 270-83]. (pmid=17516511) | # Fuchs D, Berges C, Opelz G, Daniel V, Naujokat C. Increased expression and altered subunit composition of proteasomes induced by continuous proteasome inhibition establish apoptosis resistance and hyperproliferation of Burkitt lymphoma cells. J Cell Biochem. 2008 Jan 1;103(1):[http://onlinelibrary.wiley.com/doi/10.1002/jcb.21405/pdf 270-83]. (pmid=17516511) | ||
# Imai S, Kikuchi R, Kusuhara H, Yagi S, Shiota K, Sugiyama Y. Analysis of DNA methylation and histone modification profiles of liver-specific transporters. Mol Pharmacol. 2009 Mar;75(3):[http://molpharm.aspetjournals.org/content/75/3/568.full.pdf+html 568-576] (8/3/10) | |||
# Zhang L, Littlejohn JE, Cui Y, Cao X, Peddaboina C, Smythe WR. Characterization of bortezomib-adapted I-45 mesothelioma cells.Mol Cancer. 2010 May 18;9: [http://www.molecular-cancer.com/content/pdf/1476-4598-9-110.pdf 110](8/10/10) | |||
# Kim SN, Kim NH, Lee W, Seo DW, Kim YK. Histone deacetylase inhibitor induction of P-glycoprotein transcription requires both histone deacetylase 1 dissociation and recruitment of CAAT/enhancer binding protein beta and pCAF to the promoter region. Mol Cancer Res. 2009 May;7(5):[http://mcr.aacrjournals.org/content/7/5/735.full.pdf+html 735-44] pmid=19435809 (9/16/10) | |||
# Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, Chen H, Kong X, Melamed J, Tepper CG, Kung HJ, Brodie AM, Edwards J, Qiu Y. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res. 2009 Mar 15;69(6):[http://cancerres.aacrjournals.org/content/69/6/2305.full.pdf+html 2305-13] pmid=19244107 (9/23/10) | |||
# Maeda T, Irokawa M, Arakawa H, Kuraoka E, Nozawa T, Tateoka R, Itoh Y, Nakanishi T, and Tamai I. Uptake transporter organic anion transporting polypeptide 1B3 contributes to the growth of estrogen-dependent breast cancer. J Steroid Biochem Mol Biol 2010 Oct; 122(4) [http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6T8X-50G6962-1-C&_cdi=5098&_user=16764&_pii=S0960076010002888&_origin=search&_coverDate=10%2F31%2F2010&_sk=998779995&view=c&wchp=dGLbVlW-zSkzS&md5=4e61be9c7a06b0a1c489bad90ac1d2c4&ie=/sdarticle.pdf 180-5](10/7/10) | |||
# van de Steeg E, Wagenaar E, van der Kruijssen CM, Burggraaff JE, de Waart DR, Elferink RP, Kenworthy KE, and Schinkel AH. Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs. J Clin Invest 2010 Aug 2; 120(8) 2942-52. doi:10.1172/JCI42168 pmid:20644253 | |||
# Meyer zu Schwabedissen HE, Tirona RG, Yip CS, Ho RH, Kim RB.Interplay between the nuclear receptor pregnane X receptor and the uptake transporter organic anion transporter polypeptide 1A2 selectively enhances estrogen effects in breast cancer. Cancer Res. 2008 Nov 15;68(22):[http://cancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=19010908 9338-47].PMID: 19010908 (10/28/10) | |||
#Tainton KM, Smyth MJ, Jackson JT, Tanner JE, Cerruti L, Jane SM, Darcy PK, Johnstone RW.Mutational analysis of P-glycoprotein: suppression of caspase activation in the absence of ATP-dependent drug efflux. Cell Death Differ. 2004 Sep;11(9):[http://www.nature.com/cdd/journal/v11/n9/full/4401440a.html 1028-37]. PMID: 15131592 (11/11/10) | |||
#Guo Q, Chen Y, Wu Y. Enhancing apoptosis and overcoming resistance of gemcitabine in pancreatic cancer with bortezomib: a role of death-associated protein kinase-related apoptosis-inducing protein kinase 1. Tumori. 2009 Nov-Dec;95(6):796-803. PMID: 20210246 (11/18/10) | |||
===2009 | ===2009=== | ||
# Fang C, Dean J, Smith JW. A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma. Cancer Res. 2007 Oct 1;67(19):[http://cancerres.aacrjournals.org/content/67/19/9039.full.pdf+html 9039-46]. (pmid=17909007) | # Fang C, Dean J, Smith JW. A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma. Cancer Res. 2007 Oct 1;67(19):[http://cancerres.aacrjournals.org/content/67/19/9039.full.pdf+html 9039-46]. (pmid=17909007) | ||
# Gomes AV, Young GW, Wang Y, Zong C, Eghbali M, Drews O, Lu H, Stefani E, Ping P. Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics. 2009 Feb;8(2):302-15. (pmid=18931337) | # Gomes AV, Young GW, Wang Y, Zong C, Eghbali M, Drews O, Lu H, Stefani E, Ping P. Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics. 2009 Feb;8(2):302-15. (pmid=18931337) | ||
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# Kimura Y, Yashiroda H, Kudo T, Koitabashi S, Murata S, Kakizuka A, Tanaka K. An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis.Cell. 2009 May 1;137(3):549-59. (pmid=19410548) | # Kimura Y, Yashiroda H, Kudo T, Koitabashi S, Murata S, Kakizuka A, Tanaka K. An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis.Cell. 2009 May 1;137(3):549-59. (pmid=19410548) | ||
# Yi F, Regan L. A novel class of small molecule inhibitors of Hsp90. ACS Chem Biol. 2008 Oct 17;3(10):645-54. Epub 2008 Sep 12.(pmid=18785742) | # Yi F, Regan L. A novel class of small molecule inhibitors of Hsp90. ACS Chem Biol. 2008 Oct 17;3(10):645-54. Epub 2008 Sep 12.(pmid=18785742) | ||
# Oerlemans R, Franke NE, Assaraf YG, Cloos J, van Zantwijk I, Berkers CR, Scheffer GL, Debipersad K, Vojtekova K, Lemos C, van der Heijden JW, Ylstra B, Peters GJ, Kaspers GL, Dijkmans BA, Scheper RJ, Jansen G. Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein. Blood. 2008 Sep 15;112(6):[http://bloodjournal.hematologylibrary.org/cgi/reprint/112/6/2489 2489-99]. (pmid=18565852) | |||
# Sloss CM, Wang F, Liu R, Xia L, Houston M, Ljungman D, Palladino MA, Cusack JC Jr. Proteasome inhibition activates epidermal growth factor receptor (EGFR) and EGFR-independent mitogenic kinase signaling pathways in pancreatic cancer cells. Clin Cancer Res. 2008 Aug 15;14(16):[http://clincancerres.aacrjournals.org/content/14/16/5116.full.pdf+html 5116-23]. (pmid=18698029) | |||
# Voortman J, Checińska A, Giaccone G. The proteasomal and apoptotic phenotype determine bortezomib sensitivity of non-small cell lung cancer cells. Mol Cancer. 2007 Nov 17;6:[http://www.molecular-cancer.com/content/pdf/1476-4598-6-73.pdf 73]. (pmid=18021420) | |||
# Platzer B, Richter S, Kneidinger D, Waltenberger D, Woisetschläger M, Strobl H. Aryl hydrocarbon receptor activation inhibits in vitro differentiation of human monocytes and Langerhans dendritic cells. J Immunol. 2009 Jul 1;183(1):66-74. Epub 2009 Jun 17. (pmid=19535631) | |||
# Shabek N, Herman-Bachinsky Y, Ciechanover A. Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):[http://www.pnas.org/content/106/29/11907.full.pdf+html 11907-12]. (pmid=19581590) | |||
# Comerford KM, Wallace TJ, Karhausen J, Louis NA, Montalto MC, Colgan SP. Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene. Cancer Res. 2002 Jun 15;62(12):[http://cancerres.aacrjournals.org/content/62/12/3387.full.pdf+html 3387-94]. (pmid=12067980) | |||
# Bentires-Alj M, Barbu V, Fillet M, Chariot A, Relic B, Jacobs N, Gielen J, Merville MP, Bours V. NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells. Oncogene. 2003 Jan 9;22(1):[http://www.nature.com/onc/journal/v22/n1/pdf/1206056a.pdf 90-7]. (pmid=12527911) | |||
# Kuhn DJ, Chen Q, Voorhees PM, Strader JS, Shenk KD, Sun CM, Demo SD, Bennett MK, van Leeuwen FW, Chanan-Khan AA, Orlowski RZ. Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma. Blood. 2007 Nov 1;110(9):[http://bloodjournal.hematologylibrary.org/cgi/reprint/110/9/3281 3281-90]. (pmid=17591945) | |||
# Khan MA, Oubrahim H, Stadtman ER. Inhibition of apoptosis in acute promyelocytic leukemia cells leads to increases in levels of oxidized protein and LMP2 immunoproteasome. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11560-5. Epub 2004 Jul 29. (pmid=15284441) | |||
# Xu M, Skaug B, Zeng W, Chen ZJ. A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta. Mol Cell. 2009 Oct 23;36(2):302-14. (pmid=19854138) | |||
# Comerford KM, Cummins EP, Taylor CT. c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia. Cancer Res. 2004 Dec 15;64(24):9057-61. (pmid=15604272) |
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