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==Contact Info==
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[[Image:OWWEmblem.png|thumb|right|Domenico Bellomo (an artistic interpretation)]]
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<table width="100%"><tr><td align="left"><p><span class="style1">Domenico Bellomo</span><br />
      <span class="style3">Post-doc</span><br /></p></td>
<td align="right"><p class="style2">
  Mekelweg 4<br />
  2628 CD Delft (NL)<br />
  H +31 (0)64 62 17008<br />
  T +31 (0)15 27 82378<br />
  u +31 (0)15 27 81843<br />
  B d.bellomo@tudelft.nl<br />
  </p></td>
</tr></table>
 
<table width="100%" cellspacing="10">
<tr><td align="right" width="15%%"><img src="left_bar" alt="" /></td>
<td>
<span class="style4">Personal Information</span></span>
</td></tr>
<tr><td align="right">
  Date of Birth <br />
  Place of Birth <br  />
  Nationality <br  />
  Marital Status<br />
  Home address <br  />
  e-mail address <br />
</td><td align="left">
May 5th, 1975<br />
Bari, Italy<br />
Italian<br />
Married<br />
Javastraat 65, 2585 AG Den Haag (NL)<br />
domenico.bellomo@gmail.com<br />
</td></tr></table>
  <table width="100%" cellspacing="10">
<tr><td align="right" width="15%%"><img src="left_bar" alt="" /></td>
<td>
<span class="style4">Research Interests </span></span>
</td></tr>
<tr><td align="right"><br />
</td><td align="justify">
<p align="justify">
  To gain a better understanding of the dynamics of the biochemical networks within the cell, we need to perturb the individual components of such networks, and to measure in vivo the corresponding response. I see synthetic biology primarily as a tool that can help in this effort to study the cell “from the inside”; and secondarily as a tool to re-engineer cellular functionalities according to some desired specifications. Two crucial steps in this direction are: (i) the design and experimental characterization of libraries of standard building blocks like switches, sensors, logic gates, oscillators, automata; (ii) and the development of methods for the analysis and robust design of such devices.<br />
  The latter issues are well posed only within an evolutionary perspective.<br /></p>
</td></tr></table></p>
<table width="100%" cellspacing="10">
<tr><td align="right" width="15%%"><img src="left_bar" alt="" /></td>
<td>
<span class="style4">Work Experience </span></span>
</td></tr>
<tr><td align="right" valign="top">
  Jun 06–Present
</td><td align="left">
  <strong>Post-doc</strong>, <em>Delft Bioinformatics Lab and Bioprocess Technology Group, Delft University<br />
  of Technology,</em> Delft, The Netherlands.<br />
  <u>Research</u>: reconstruction of metabolic networks; relation between structure and dynamics in
  biochemical networks; analysis, design and standardization of synthetic networks.<br />
  <u>Other activities:</u> initiator and supervisor of 2008 and 2009 TUDelft iGEM (International Genetically
  Engineered Machine competition) teams; initiator and organizer of the biweekly NO-MEC
  meetings on metabolic networks modeling.
</td></tr>
  <tr><td align="right" valign="top">
  Apr 05–May 06
</td>
<td align="left">
  <strong>R&amp;D engineer</strong><em>, IHC systems B.V.</em> , Sliedrecht, The Netherlands.<br />
  <u>Tasks</u>: design of stochastic filters for on-line parameter estimation (e.g. Kalman filters, particle
  filters, etc.).<br />
  <u>Completed projects:</u> grain-size estimation in water slurry mixture, anchor position estimation,
  overflow losses estimation, swing speed control.<br />
</td></tr>
</table>


*Domenico Bellomo
*Delft University of Technology
*Julianalaan 67
*2628 BC
*Delft, The Netherlands
*[[Special:Emailuser/Domenico Bellomo|Email me through OpenWetWare]]


I work in the ICT research group at Delft University of Technology. I learned about OpenWetWare through the iGEM competition, and I've joined because I would like to edit the work of 2008 TUDelft iGEM team.
<table width="100%" cellspacing="10">
<tr><td align="right" width="15%%"><img src="left_bar" alt="" /></td>
<td>
<span class="style4">Education </span></span>
</td></tr>
<tr><td align="right" valign="top">
  Jan 01–Mar 05
</td><td align="left">
  <strong>PhD in Electrical Engineering</strong>, <em>, Politecnico di Bari</em>, Bari, Italy.<br />
  <u>Main topic:</u>  Lyapunov based design of adaptive fuzzy controllers for nonlinear servo-drives.<br />
  <u>Secondary project:</u> design of a decision support system for the optimization of mechanical
  ventilation settings, in patients affected by acute respiratory syndrome
</td></tr>
  <tr><td align="right" valign="top">
  Oct 02–Oct 03
</td>
<td align="left">
  <strong>Visiting student</strong><em>,Delft Center for Systems and Control, Delft University of Technology, </em> , Delft, The Netherlands.<br />
  <u>Research subject:</u>on line identification of fuzzy models.<br />
</td></tr>
  <tr><td align="right" valign="top">
  Sep 94–Jul 01
</td>
<td align="left">
  <strong>Laurea (BA &amp; MSc) in Electrical Engineering</strong><em>, Politecnico di Bari,</em> Bari, Italy.<br />
  <u>Thesis:</u>Intelligent Control of Nonlinear Systems: a Fuzzy Logic Based Approach<br />
    Graduation mark: 110/110 cum laude
</td></tr>
    <tr><td align="right" valign="top">
  Sep 91–Aug 94
</td>
<td align="left">
  <strong>High School,</strong><em>Scientific Lyceum G. Salvemini,</em> Bari, Italy.<br />
  <u>Thesis:</u>Intelligent Control of Nonlinear Systems: a Fuzzy Logic Based Approach<br />
    Graduation mark: 60/60
</td></tr>
</table>
<table width="100%" cellspacing="10">
<tr><td align="right" width="15%%"><img src="left_bar" alt="" /></td>
<td>
<span class="style4">Teaching Assistant Experience </span></span>
</td></tr>
<tr><td align="right"><br />
</td><td align="left">
<li>Functional Genomics &amp; Systems Biology (MSc-level), 2009</li>
<li>Advanced course in Bioinformatics (postgraduate level), 2008 </li>
<li>Computer-Controlled Systems (MSc-level), 2002, 2003</li>
</td></tr></table>


==Education==
<table width="100%" cellspacing="10">
<!--Include info about your educational background-->
<tr><td align="right" width="15%%"><img src="left_bar" alt="" /></td>
* Year, PhD, Institute
<td>
* Year, MS, Institute
<span class="style4">Recently supervised MSc projects </span></span>
* Year, BS, Institute
</td></tr>
<tr><td align="right"><br />
</td><td align="left">
  <li>B. van den Berg, (supervisors: D. Bellomo, M.J.T. Reinders), “Automated design of synthetic biological systems using standard parts”, Nov 2008- present.</li>
  <li>P. van Nes (supervisors: D. Bellomo, D. de Ridder and M.J.T. Reinders), “Inferring dynamic properties of metabolic networks from their structural information”, Delft University of Technology, April 4 2008.</li>
  <li>J. Yong-A-Poi (supervisors: E.P. van Someren, D. Bellomo and M.J.T. Reinders), “Adaptive least absolute regression network analysis improves genetic network reconstruction by employing prior knowledge”, Delft University of Technology, March 28 2008.</li>
</td></tr></table>


==Research interests==
  <table width="100%" cellspacing="10">
<!-- Feel free to add brief descriptions to your research interests as well -->
<tr><td align="right" width="15%%"><img src="left_bar" alt="" /></td>
# Interest 1
<td>
# Interest 2
<span class="style4">Selected postgraduate courses </span></span>
# Interest 3
</td></tr>
<tr><td align="right"><br />
</td><td align="left">
  <li>² 5th Cytoscape public symposium and developer retreat, Amsterdam, The Netherlands, Nov 2007.</li>
  <li>Advanced course on applied genomics of industrial fermentation, Wageningen, The Netherlands, Oct 2006</li>
  <li>Genome access course, Cold Spring Harbor Laboratory, New York, Nov 2005.</li>
</td></tr></table>


==Publications==
  <p><span class="style4">  <img src="left_bar" alt="" />Computer skills </span></p>
<biblio>
  <br />
  <p>Tools Latex, Office Packages MATLAB, COPASI, CellNetAnalyzer,<br />
  Genedata, LabVIEW, dSPACE<br />
  Languages C, C++ Platforms Windows, Linux<br />
  Wet-Lab literacy<br />
  Plasmid mini-prep, restriction and ligation (Bio-Brick standards), competent cells transformation,<br />
  gel electrophoresis, PCR.<br /></p>
  <p> <span class="style4"><img src="left_bar" alt="" />Languages </span></p>
  <br />
  <p>
  Italian Fluent My native language.<br />
  English Fluent Speaking, reading, and writing.<br />
  Dutch Intermediate Delftse methode beginners course: 94/100<br />
  German Basic Reading<br /></p>
  <p><span class="style4"><img src="left_bar" alt="" />Hobbies </span></p>
  <br />
  <p>Reading all kind of popular science books, novels, poetry and techno-thrillers; theater;<br />
  music; traveling; playing soccer, swimming, table-tennis.<br /></p>
 
  <p> <span class="style4"><img src="left_bar" alt="" />Publications </span></p>
  <br />
  <p>
  Systems and Synthetic Biology </p><br />
  <p>
  [1b] O. M. J. A Stassen, R. J. J. Jorna, B. A. van den Berg, R. Haghi, F. Ehtemam, S. M.<br />
  Flipse, J. A Kiers, M. J. L de Groot, I. E. Nikerel, D. Bellomo,“Toward tunable RNA<br />
  thermo-switches for temperature dependent gene expression”, to be submitted.<br />
  [2b] F. Menolascina, D. Bellomo, T. Maiwald, V. Bevilacqua, C. Ciminelli, A. Paradiso, and<br />
  S. Tommasi, “Developing optimal input design strategies in cancer systems biology with<br />
  applications to micro-fluidic device engineering”, BMC Bioinformatics 2009, in press<br />
  [3b] P. van Nes, D. Bellomo, M.J.T. Reinders and D. de Ridder, “Stability from structure:<br />
  metabolic networks are unlike other biological networks”, EURASIP Journal on<br />
  Bioinformatics and Systems Biology, vol. 2009, pp. Article ID 630695, 2009.<br />
  [4b] D. Bellomo, D. de Ridder, S. Rossell, P.J.T. Verheijen, M.J.T. Reinders and J.J.<br />
  Heijnen, “Identifying the regulatory structure of metabolic networks: a constrained<br />
  optimization approach”, Proceedings of the 14th annual conference of the Advanced<br />
  School for Computing and Imaging, pp. 250-257, 2008.<br />
  [5b] D. Bellomo, P. van Nes, M.J.T. Reinders and D. de Ridder, “Stability cannot be derived<br />
  from local structure in biochemical network”, Proceedings of the 3rd international<br />
  conference on bio-inspired models of network, information, and computing systems,<br />
  ICST, Gent, Belgium, 2008.<br />
  [6b] D. Bellomo, D. de Ridder, J.J. Heijnen, M. J.T. Reinders, W. A. van Winden, P.J.T.<br />
  Verheijen, “Identifiability of metabolic networks in pulse experiments”, Proceedings of<br />
  the 13th annual conference of the Advanced School for Computing and Imaging, 2007.<br />
  </p>
  <p>
  Systems and Control Theory</p><br />
  <p>
  [1c] D. Bellomo, D. Naso, R. Babuška, “Adaptive fuzzy control of a non-linear servo-drive:<br />
  theory and experimental results”, Engineering Applications of Artificial Intelligence, vol.<br />
  21, no. 6, September 2008.<br />
  [2c] D. Bellomo, Babuška R., Naso, D., “Adaptive fuzzy control for speed-reference tracking<br />
  in nonlinear servo drives”, Proceeding of 14th IFAC Symposium on System Identification,<br />
  March 29-31, 2006, Newcastle, Australia.<br />
  [3c] D. Bellomo, Naso, D., Babuška R., “Experimental comparison of adaptive fuzzy controllers”,<br />
  Proceeding of FuzzIEEE 2005, Conference on Fuzzy systems , May 22-25,<br />
  Reno, Nevada, USA.<br />
  [4c] D. Bellomo, D. Naso, B. Turchiano, R. Babuška, “Composite adaptation in adaptive<br />
  fuzzy control”, Proceedings of 16th IFAC World Congress, Prague, Czech Republic, July<br />
  4 to July 8, 2005<br />
  [5c] D. Bellomo, D. Naso, R. Babuška, “Parameter convergence in adaptive fuzzy control”,<br />
  Proceedings of the 1st International Conference on Informatics in Control, Automation<br />
  and Robotics, vol.2, 25-28 August 2004, Setubal, Portugal.<br />
  [6c] D. Bellomo, D. Naso, B. Turchiano, “Improving genetic algorithms: an approach based<br />
  on multi-elitism and Lamarckian mutation”, Proceedings of 2002 IEEE International<br />
  Conference on Systems, Man and Cybernetics, Vol. 4 , 6-9 Oct. 2002.<br />
  </p>
  <p> <span class="style4"> <img src="left_bar" alt="" />References </span></p>
  <br />
  <p>
  Prof. Dr. Ir. Marcel J.T. Reinders<br />
  Delft Bioinformatics Lab Phone:+31 (0)15 27 86424<br />
  Delft University of Technology Fax: +31 (0)15 27 81843<br />
  Mekelweg 4, 2628 CD Delft, NL Email: M.J.T.Reinders [AT] tudelft.nl<br />
  Prof. Dr. Han de Winde<br />
  Chairman of the Department of Biotechnology Phone:+31 (0)15 27 86659<br />
  Delft University of Technology<br />
  Julianalaan 67, 2628 BC Delft, NL Email: j.h.dewinde [AT] tudelft.nl<br />
  Prof. Dr. Ir. Sef Heijnen<br />
  Bio-process Technology Group Phone:+31 (0)15 278 2341<br />
  Delft University of Technology<br />
  Julianalaan 67, 2628 BC Delft, NL Email: J.J.Heijnen [AT] tudelft.nl<br />
  Prof. Dr. Robert Babuška<br />
  Delft Center for Systems and Control Phone:+31 (0)15 27 85117<br />
  Delft University of Technology Fax: +31 (0)15 27 86679<br />
  Mekelweg 2, 2628 CD Delft, NL Email: r.babuska [AT] dcsc.tudelft.nl<br />
  </p>
  <p>
  Updated<br />
  October 22, 2009<br />
  </p>
</body>


</biblio>
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Revision as of 21:57, 3 November 2009

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Domenico Bellomo
Post-doc

 

 Mekelweg 4

 2628 CD Delft (NL)

 H +31 (0)64 62 17008

 T +31 (0)15 27 82378

 u +31 (0)15 27 81843

 B d.bellomo@tudelft.nl

<img src="left_bar" alt="" /> 
Personal Information

 Date of Birth 

 Place of Birth 

 Nationality 

 Marital Status
 
 Home address 

 e-mail address 


May 5th, 1975

Bari, Italy

Italian

Married

Javastraat 65, 2585 AG Den Haag (NL)

domenico.bellomo@gmail.com
<img src="left_bar" alt="" /> 
Research Interests

To gain a better understanding of the dynamics of the biochemical networks within the cell, we need to perturb the individual components of such networks, and to measure in vivo the corresponding response. I see synthetic biology primarily as a tool that can help in this effort to study the cell “from the inside”; and secondarily as a tool to re-engineer cellular functionalities according to some desired specifications. Two crucial steps in this direction are: (i) the design and experimental characterization of libraries of standard building blocks like switches, sensors, logic gates, oscillators, automata; (ii) and the development of methods for the analysis and robust design of such devices.
The latter issues are well posed only within an evolutionary perspective.

<img src="left_bar" alt="" /> 
Work Experience 

 Jun 06–Present 

 Post-doc, Delft Bioinformatics Lab and Bioprocess Technology Group, Delft University

 of Technology, Delft, The Netherlands.

 Research: reconstruction of metabolic networks; relation between structure and dynamics in
 biochemical networks; analysis, design and standardization of synthetic networks.

 Other activities: initiator and supervisor of 2008 and 2009 TUDelft iGEM (International Genetically
 Engineered Machine competition) teams; initiator and organizer of the biweekly NO-MEC
 meetings on metabolic networks modeling.

 Apr 05–May 06 

 R&D engineer, IHC systems B.V. , Sliedrecht, The Netherlands.

 Tasks: design of stochastic filters for on-line parameter estimation (e.g. Kalman filters, particle
 filters, etc.).

 Completed projects: grain-size estimation in water slurry mixture, anchor position estimation,
 overflow losses estimation, swing speed control.


<img src="left_bar" alt="" /> 
Education 

 Jan 01–Mar 05

 PhD in Electrical Engineering, , Politecnico di Bari, Bari, Italy.

 Main topic:  Lyapunov based design of adaptive fuzzy controllers for nonlinear servo-drives.

 Secondary project: design of a decision support system for the optimization of mechanical
 ventilation settings, in patients affected by acute respiratory syndrome

 Oct 02–Oct 03 

 Visiting student,Delft Center for Systems and Control, Delft University of Technology,  , Delft, The Netherlands.

 Research subject:on line identification of fuzzy models.


 Sep 94–Jul 01

 Laurea (BA & MSc) in Electrical Engineering, Politecnico di Bari, Bari, Italy.

 Thesis:Intelligent Control of Nonlinear Systems: a Fuzzy Logic Based Approach

   Graduation mark: 110/110 cum laude

 Sep 91–Aug 94 

 High School,Scientific Lyceum G. Salvemini, Bari, Italy.

 Thesis:Intelligent Control of Nonlinear Systems: a Fuzzy Logic Based Approach

   Graduation mark: 60/60


<img src="left_bar" alt="" /> 
Teaching Assistant Experience

  • Functional Genomics & Systems Biology (MSc-level), 2009
  • Advanced course in Bioinformatics (postgraduate level), 2008
  • Computer-Controlled Systems (MSc-level), 2002, 2003
    • <img src="left_bar" alt="" /> 
    Recently supervised MSc projects

  • B. van den Berg, (supervisors: D. Bellomo, M.J.T. Reinders), “Automated design of synthetic biological systems using standard parts”, Nov 2008- present.
  • P. van Nes (supervisors: D. Bellomo, D. de Ridder and M.J.T. Reinders), “Inferring dynamic properties of metabolic networks from their structural information”, Delft University of Technology, April 4 2008.
  • J. Yong-A-Poi (supervisors: E.P. van Someren, D. Bellomo and M.J.T. Reinders), “Adaptive least absolute regression network analysis improves genetic network reconstruction by employing prior knowledge”, Delft University of Technology, March 28 2008.
    • <img src="left_bar" alt="" /> 
    Selected postgraduate courses

  • ² 5th Cytoscape public symposium and developer retreat, Amsterdam, The Netherlands, Nov 2007.
  • Advanced course on applied genomics of industrial fermentation, Wageningen, The Netherlands, Oct 2006
  • Genome access course, Cold Spring Harbor Laboratory, New York, Nov 2005.

    • <img src="left_bar" alt="" />Computer skills

    Tools Latex, Office Packages MATLAB, COPASI, CellNetAnalyzer,
    Genedata, LabVIEW, dSPACE
    Languages C, C++ Platforms Windows, Linux
    Wet-Lab literacy
    Plasmid mini-prep, restriction and ligation (Bio-Brick standards), competent cells transformation,
    gel electrophoresis, PCR.

    <img src="left_bar" alt="" />Languages

    Italian Fluent My native language.
    English Fluent Speaking, reading, and writing.
    Dutch Intermediate Delftse methode beginners course: 94/100
    German Basic Reading

    <img src="left_bar" alt="" />Hobbies

    Reading all kind of popular science books, novels, poetry and techno-thrillers; theater;
    music; traveling; playing soccer, swimming, table-tennis.

    <img src="left_bar" alt="" />Publications

    Systems and Synthetic Biology


    [1b] O. M. J. A Stassen, R. J. J. Jorna, B. A. van den Berg, R. Haghi, F. Ehtemam, S. M.
    Flipse, J. A Kiers, M. J. L de Groot, I. E. Nikerel, D. Bellomo,“Toward tunable RNA
    thermo-switches for temperature dependent gene expression”, to be submitted.
    [2b] F. Menolascina, D. Bellomo, T. Maiwald, V. Bevilacqua, C. Ciminelli, A. Paradiso, and
    S. Tommasi, “Developing optimal input design strategies in cancer systems biology with
    applications to micro-fluidic device engineering”, BMC Bioinformatics 2009, in press
    [3b] P. van Nes, D. Bellomo, M.J.T. Reinders and D. de Ridder, “Stability from structure:
    metabolic networks are unlike other biological networks”, EURASIP Journal on
    Bioinformatics and Systems Biology, vol. 2009, pp. Article ID 630695, 2009.
    [4b] D. Bellomo, D. de Ridder, S. Rossell, P.J.T. Verheijen, M.J.T. Reinders and J.J.
    Heijnen, “Identifying the regulatory structure of metabolic networks: a constrained
    optimization approach”, Proceedings of the 14th annual conference of the Advanced
    School for Computing and Imaging, pp. 250-257, 2008.
    [5b] D. Bellomo, P. van Nes, M.J.T. Reinders and D. de Ridder, “Stability cannot be derived
    from local structure in biochemical network”, Proceedings of the 3rd international
    conference on bio-inspired models of network, information, and computing systems,
    ICST, Gent, Belgium, 2008.
    [6b] D. Bellomo, D. de Ridder, J.J. Heijnen, M. J.T. Reinders, W. A. van Winden, P.J.T.
    Verheijen, “Identifiability of metabolic networks in pulse experiments”, Proceedings of
    the 13th annual conference of the Advanced School for Computing and Imaging, 2007.

    Systems and Control Theory


    [1c] D. Bellomo, D. Naso, R. Babuška, “Adaptive fuzzy control of a non-linear servo-drive:
    theory and experimental results”, Engineering Applications of Artificial Intelligence, vol.
    21, no. 6, September 2008.
    [2c] D. Bellomo, Babuška R., Naso, D., “Adaptive fuzzy control for speed-reference tracking
    in nonlinear servo drives”, Proceeding of 14th IFAC Symposium on System Identification,
    March 29-31, 2006, Newcastle, Australia.
    [3c] D. Bellomo, Naso, D., Babuška R., “Experimental comparison of adaptive fuzzy controllers”,
    Proceeding of FuzzIEEE 2005, Conference on Fuzzy systems , May 22-25,
    Reno, Nevada, USA.
    [4c] D. Bellomo, D. Naso, B. Turchiano, R. Babuška, “Composite adaptation in adaptive
    fuzzy control”, Proceedings of 16th IFAC World Congress, Prague, Czech Republic, July
    4 to July 8, 2005
    [5c] D. Bellomo, D. Naso, R. Babuška, “Parameter convergence in adaptive fuzzy control”,
    Proceedings of the 1st International Conference on Informatics in Control, Automation
    and Robotics, vol.2, 25-28 August 2004, Setubal, Portugal.
    [6c] D. Bellomo, D. Naso, B. Turchiano, “Improving genetic algorithms: an approach based
    on multi-elitism and Lamarckian mutation”, Proceedings of 2002 IEEE International
    Conference on Systems, Man and Cybernetics, Vol. 4 , 6-9 Oct. 2002.

    <img src="left_bar" alt="" />References

    Prof. Dr. Ir. Marcel J.T. Reinders
    Delft Bioinformatics Lab Phone:+31 (0)15 27 86424
    Delft University of Technology Fax: +31 (0)15 27 81843
    Mekelweg 4, 2628 CD Delft, NL Email: M.J.T.Reinders [AT] tudelft.nl
    Prof. Dr. Han de Winde
    Chairman of the Department of Biotechnology Phone:+31 (0)15 27 86659
    Delft University of Technology
    Julianalaan 67, 2628 BC Delft, NL Email: j.h.dewinde [AT] tudelft.nl
    Prof. Dr. Ir. Sef Heijnen
    Bio-process Technology Group Phone:+31 (0)15 278 2341
    Delft University of Technology
    Julianalaan 67, 2628 BC Delft, NL Email: J.J.Heijnen [AT] tudelft.nl
    Prof. Dr. Robert Babuška
    Delft Center for Systems and Control Phone:+31 (0)15 27 85117
    Delft University of Technology Fax: +31 (0)15 27 86679
    Mekelweg 2, 2628 CD Delft, NL Email: r.babuska [AT] dcsc.tudelft.nl

    Updated
    October 22, 2009

    </body>

    </html>

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