IGEM:IMPERIAL/2008/New/Home: Difference between revisions

From OpenWetWare
Jump to navigationJump to search
← Older editNewer edit →
Qin Qi (talk | contribs)
680 edits
No edit summary
Qin Qi (talk | contribs)
680 edits
No edit summary
Line 20: Line 20:
{| width="100%"
{| width="100%"
|  
|  
<align="left">Schematic Overview
<align="left">Schematic Overview</align="left">
[[Image:Imperial_2008_Bioprinter_Cartoon.png |380px| Overview of our planned system]]  
[[Image:Imperial_2008_Bioprinter_Cartoon.png |380px| Overview of our planned system]]  
<br>
<br>
<br>
<br>
<align="left">Simplified Circuit Diagram
<align="left">Simplified Circuit Diagram</align="left">
[[Image:Imperial_2008_Basic_Circuit.jpg | 380px |Basic Circuit Diagram]]
[[Image:Imperial_2008_Basic_Circuit.jpg | 380px |Basic Circuit Diagram]]
| valign="top" |
| valign="top" |

Revision as of 14:25, 11 September 2008

<html> <style type="text/css"> .firstHeading {display: none;} </style> </html> <html> <style type="text/css"> 

   table.calendar          { margin:0; padding:2px; }

table.calendar td { margin:0; padding:1px; vertical-align:top; } table.month .heading td { padding:1px; background-color:#FFFFFF; text-align:center; font-size:120%; font-weight:bold; } table.month .dow td { text-align:center; font-size:110%; } table.month td.today { background-color:#3366FF } table.month td { 

   border:2px;
   margin:0;
   padding:0pt 1.5pt;
   font-size:8pt;
   text-align:right;
   background-color:#FFFFFF;
   }
  1. bodyContent table.month a { background:none; padding:0 }

.day-active { font-weight:bold; } .day-empty { color:black; } </style> </html>

<html><script language="JavaScript">

var timeout = 250; var closetimer = 0; var ddmenuitem = 0;

// open hidden layer function mopen(id) { // cancel close timer mcancelclosetime(); // close old layer if(ddmenuitem) ddmenuitem.style.visibility = 'hidden'; // get new layer and show it ddmenuitem = document.getElementById(id); ddmenuitem.style.visibility = 'visible'; } // close showed layer function mclose() { if(ddmenuitem) ddmenuitem.style.visibility = 'hidden'; } // go close timer function mclosetime() { closetimer = window.setTimeout(mclose, timeout); } // cancel close timer function mcancelclosetime() { if(closetimer) { window.clearTimeout(closetimer); closetimer = null; } } // close layer when click-out //document.onclick = mclose; </script>




</html>
<html><style type="text/css">

div.Section { font:11pt/16pt Calibri, Verdana, Arial, Geneva, sans-serif; background-image: url(http://openwetware.org/images/a/a0/Background.PNG); background-size: 100%; background-origin: content; }

/* Text (paragraphs) */ div.Section p { font:11pt/16pt Calibri, Verdana, Arial, Geneva, sans-serif; text-align:justify; margin-top:0px; margin-left:30px; margin-right:30px; }

/* Headings */ div.Section h1 { font:22pt Calibri, Verdana, Arial, Geneva, sans-serif; text-align:left; color:#3366FF; font-weight:bold; }

/* Subheadings */ div.Section h2 { font:18pt Calibri, Verdana, Arial, Geneva, sans-serif; color:#3366FF; margin-left:5px; font-weight:bold; }

/* Subsubheadings */ div.Section h3 { font:22pt Calibri, Verdana, Arial, sans-serif; color:#E5EBFF; margin-left:10px; font-weight:bold; }

/* Subsubsubheadings */ div.Section h4 { font:22pt Calibri, Verdana, Arial, sans-serif; color:#2B48B3; margin-left:10px; font-weight:bold; }

/* Subsubsubsubheadings */ div.Section h5 { font:12pt Calibri, Verdana, Arial, sans-serif; color:#3366FF; margin-left:20px; }

/* References */ div.Section h6 { font:12pt Calibri, Verdana, Arial, sans-serif; font-weight:bold; font-style:italic; color:#3366FF; margin-left:25px; }

/* Hyperlinks */ div.Section a { }

div.Section a:hover { }

/* Tables */ div.Section td { font:11pt/16pt Calibri, Verdana, Arial, Geneva, sans-serif; text-align:justify; vertical-align:top; padding:2px 4px 2px 4px; }

/* Lists */ div.Section li { font:11pt/16pt Calibri, Verdana, Arial, Geneva, sans-serif; text-align:left; margin-top:0px; margin-left:30px; margin-right:0px; }

/* TOC stuff */ table.toc { margin-left:10px; }

table.toc li { font: 11pt/16pt Calibri, Verdana, Arial, Geneva, sans-serif; text-align: justify; margin-top: 0px; margin-left:2px; margin-right:2px; }

/* [edit] links */ span.editsection { color:#BBBBBB; font-size:10pt; font-weight:normal; font-style:normal; vertical-align:bottom; }

span.editsection a { color:#BBBBBB; font-size:10pt; font-weight:normal; font-style:normal; vertical-align:bottom; }

span.editsection a:hover { color:#3366FF; font-size:10pt; font-weight:normal; font-style:normal; vertical-align:bottom; }

/* Drop-down Menu */

  1. sddm {

margin: 0; padding: 0; z-index: 30 margin: 0; padding: 0; float: center; font: bold 12pt Calibri, Verdana, Arial, Geneva, sans-serif; border: 0px; list-style: none; }

  1. sddm a {

display: block; margin: 0px 0px 0px 0px; padding: 0 0 12px 0; color: #FFFFFF; text-align: center; text-decoration: none; }

  1. sddm a:hover {

border: 0px }

  1. sddm div {

position: absolute; visibility: hidden; margin: 0; padding: 0; background: #66aadd; border: 1px solid #66aadd } #sddm div a { position: relative; left: 0; display: block; margin: 0; padding: 5px 10px; width: auto; white-space: nowrap; text-align: left; text-decoration: none; background: #FFFFFF; color: #2875DE; font: 11pt Calibri, Verdana, Arial, Geneva, sans-serif } #sddm div a:hover { background: #66aadd; color: #FFFFFF } </style></html>


Welcome to the Imperial 2008 iGEM project page. It's Thursday, February 26 and a great day to read about an awesome iGEM project!


<html>
<embed width=640px src="http://openwetware.org/images/5/52/Imperial_2008_Movie.mov"></embed>
</html>


For the 2008 iGEM competition, the Imperial team is designing a biofabricator using the Gram-positive Bacillus subtilis bacterium as our chassis. We hope to exert fine control over its movement via a recently-discovered clutch mechanism. Using light as our stimulus to localise the bacteria, we then intend to trigger production and secretion of a self-assembling biomaterial in a set 3D pattern.

3D bio-scaffold materials have many applications in tissue engineering. Our blue-sky aim is to synthesise a precise biofabricator that can accelerate tissue engineering processes, hence making a contribution to the field of regenerative medicine.



<align="left">Schematic Overview</align="left"> Overview of our planned system

<align="left">Simplified Circuit Diagram</align="left"> Basic Circuit Diagram

This diagram gives an overview of how our system works. Initially, B. subtilis are motile and are not producing biomaterials. If we want to construct a bio-scaffold with an "I" shape in 3D, we shine a 3D hologram of the correct wavelength (red is used as an arbitrary example here) onto the growth medium.

Bacteria will sense that light and triggers start to produce a clutch molecule. This disengages the flagella from the motor quite quickly, rendering the subtilis stationary. Coupled with the clutch is a gene for expression for biomaterial synthesis. Should any individuals stray from the correct area, the clutch should disengage and material synthesis should stop.

We hope to build up our bio-scaffold material pixel by pixel in the defined area - the basis of our 3D biofabrication process.

>>> Project Specifications >>>



Imperial College's iGEM team 2008 would like to thank our sponsors:

<html>
<a href=http://www.bio-rad.com/><img src=http://i59.photobucket.com/albums/g305/Timpski/BioRad.png></a><a href=http://www.fisher.co.uk/><img height=50px src=http://i59.photobucket.com/albums/g305/Timpski/FisherScientific.jpg></a><a href=http://www.geneart.com/><img src=http://i59.photobucket.com/albums/g305/Timpski/GeneArt.gif></a><a href=http://www.vwr.com/index.htm><img height=50px src=http://i59.photobucket.com/albums/g305/Timpski/VWR.jpg></a>
</html>
<html>
    </html>[[IGEM:IMPERIAL/2008/New/{{{1}}}|< Previous]]<html>
    <a href="#">Back to top</a>
    </html>[[IGEM:IMPERIAL/2008/New/{{{2}}}|Next >]]<html>
</html>
Retrieved from "https://openwetware.org/mediawiki/index.php?title=IGEM:IMPERIAL/2008/New/Home&oldid=241124"