Biomod/2012/UTokyo/UT-Komaba/Idea: Difference between revisions
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;<math>\overline{B}</math>: light up when there is B | ;<math>\overline{B}</math>: light up when there is B | ||
These pixels are actually DNA strands. They | These pixels are actually DNA strands. They stand on DNA origami, and light up when they hybridize. Please note that both α and β don't light up at the same time, because bistable system makes the state "There is only A" or "There is only B" . | ||
These four kinds of pixels enable us to switch pictures. | These four kinds of pixels enable us to switch pictures. | ||
Revision as of 13:45, 1 September 2012
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Mission
Now that there are many tablet computers, our goal is to create the world's smallest tablet ! We are designing and constructing 15x15 pixel display made of DNA origami. We aim to show animation on that display, using bistable system.
Bistable System
What is Bistable System?
Bistable system enables us to express two exclusive states, using network of chemical reaction.
For example, we represent two states by materials A and B. Bistable system uses reaction network like right picture. In this network, A promotes production of A itself and iB(i means inhibition), and B promotes B itself and iA. On the other hand, iA inhibits production of A and iB inhibits production of B. There are also reactions that decompose A, B, iA, and iB.
If A is even bit more than B, this network promotes production of A and decomposition of B (detail is shown in Simulation). Afterwards there will be only A and vice versa. Thus bistable system make two states "There is only A" and "There is only B".
Method
To realize bistable system, we used DNA.
- production of A,B,iA,iB
So is B and iA.
- inhibition of production of A,B
So is B.
- decomposition of A,B,iA,iB
DNA tablet
What is DNA tablet ?
The DNA tablet shows you the two different pictures in response to its environmental change.
There are four kinds of pixels:
- [math]\displaystyle{ \Theta }[/math]
- always light up
- [math]\displaystyle{ \Phi }[/math]
- always black out
- [math]\displaystyle{ \overline{A} }[/math]
- light up when there is A
- [math]\displaystyle{ \overline{B} }[/math]
- light up when there is B
These pixels are actually DNA strands. They stand on DNA origami, and light up when they hybridize. Please note that both α and β don't light up at the same time, because bistable system makes the state "There is only A" or "There is only B" .
These four kinds of pixels enable us to switch pictures.
How to see it
We'll use AFM to see DNA tablet. We think AFM detects the difference between hybridized staple strands and non-hybridized ones.
