Smolke:Reprints

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Publications Reviewed Journal Publications Smolke CD. Cell biology. It's the DNA that counts. Science. 2009 May 29;324(5931):1156-7. DOI:10.1126/science.1174843 | Beisel CL and Smolke CD. Design principles for riboswitch function. PLoS Comput Biol. 2009 Apr;5(4):e1000363. DOI:10.1371/journal.pcbi.1000363 | Win MN, Liang JC, and Smolke CD. Frameworks for programming biological function through RNA parts and devices. Chem Biol. 2009 Mar 27;16(3):298-310. DOI:10.1016/j.chembiol.2009.02.011 | Hoff KG, Goodlitt R, Li R, Smolke CD, and Silberg JJ. Fluorescence detection of a protein-bound 2Fe2S cluster. Chembiochem. 2009 Mar 2;10(4):667-70. DOI:10.1002/cbic.200800747 | Bayer TS, Hoff KG, Beisel CL, Lee JJ, and Smolke CD. Synthetic control of a fitness tradeoff in yeast nitrogen metabolism. J Biol Eng. 2009 Jan 2;3:1. DOI:10.1186/1754-1611-3-1 | Beisel CL, Bayer TS, Hoff KG, and Smolke CD. Model-guided design of ligand-regulated RNAi for programmable control of gene expression. Mol Syst Biol. 2008;4:224. DOI:10.1038/msb.2008.62 | Win MN and Smolke CD. Higher-order cellular information processing with synthetic RNA devices. Science. 2008 Oct 17;322(5900):456-60. DOI:10.1126/science.1160311 | Hawkins KM and Smolke CD. Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae. Nat Chem Biol. 2008 Sep;4(9):564-73. DOI:10.1038/nchembio.105 | Win MN and Smolke CD. A modular and extensible RNA-based gene-regulatory platform for engineering cellular function. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14283-8. DOI:10.1073/pnas.0703961104 | Win MN, Klein JS, and Smolke CD. Codeine-binding RNA aptamers and rapid determination of their binding constants using a direct coupling surface plasmon resonance assay. Nucleic Acids Res. 2006;34(19):5670-82. DOI:10.1093/nar/gkl718 | Hawkins KM and Smolke CD. The regulatory roles of the galactose permease and kinase in the induction response of the GAL network in Saccharomyces cerevisiae. J Biol Chem. 2006 May 12;281(19):13485-13492. DOI:10.1074/jbc.M512317200 | Pfleger BF, Pitera DJ, Smolke CD, and Keasling JD. Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes. Nat Biotechnol. 2006 Aug;24(8):1027-32. DOI:10.1038/nbt1226 | Bayer TS and Smolke CD. Programmable ligand-controlled riboregulators of eukaryotic gene expression. Nat Biotechnol. 2005 Mar;23(3):337-43. DOI:10.1038/nbt1069 | Isaacs FJ and Collins JJ. Plug-and-play with RNA. Nat Biotechnol. 2005 Mar;23(3):306-7. DOI:10.1038/nbt0305-306 | Smolke CD and Keasling JD. Effect of gene location, mRNA secondary structures, and RNase sites on expression of two genes in an engineered operon. Biotechnol Bioeng. 2002 Dec 30;80(7):762-76. DOI:10.1002/bit.10434 | Smolke CD and Keasling JD. Effect of copy number and mRNA processing and stabilization on transcript and protein levels from an engineered dual-gene operon. Biotechnol Bioeng. 2002 May 20;78(4):412-24. DOI:10.1002/bit.10218 | Smolke CD, Khlebnikov A, and Keasling JD. Effects of transcription induction homogeneity and transcript stability on expression of two genes in a constructed operon. Appl Microbiol Biotechnol. 2001 Dec;57(5-6):689-96. DOI:10.1007/s002530100812 | Smolke CD, Martin VJ, and Keasling JD. Controlling the metabolic flux through the carotenoid pathway using directed mRNA processing and stabilization. Metab Eng. 2001 Oct;3(4):313-21. DOI:10.1006/mben.2001.0194 | Smolke CD, Carrier TA, and Keasling JD. Coordinated, differential expression of two genes through directed mRNA cleavage and stabilization by secondary structures. Appl Environ Microbiol. 2000 Dec;66(12):5399-405. DOI:10.1128/AEM.66.12.5399-5405.2000 | Please Note: An early online correction to (PNAS. 2007. 104:14283-8) has been published here. We will add the additional PMID above once PNAS has processed the correction. Additional detail on data processing and raw data for (Science. 2008. 322:456-60.) is provided here. Non-Peer-Reviewed Publications Win MN and Smolke CD. RNA as a versatile and powerful platform for engineering genetic regulatory tools. Biotechnol Genet Eng Rev. 2007;24:311-46. DOI:10.1080/02648725.2007.10648106 | Bio FAB Group, Baker D, Church G, Collins J, Endy D, Jacobson J, Keasling J, Modrich P, Smolke C, and Weiss R. Engineering life: building a fab for biology. Sci Am. 2006 Jun;294(6):44-51. DOI:10.1038/scientificamerican0606-44 | Smolke, C. 2005. Molecular switches for cellular sensors. Engineering and Applied Science 4, 28-37 Martin, V.J.J., Smolke, C.D., Keasling, J.D. (2002) Redesigning cells for the production of complex organic molecules. ASM News 68, 336-343. Books and Book Chapters Smolke, C.D., editor (2009) Handbook for Metabolic Pathway Engineering. San Diego: CRC Press. In press. Smolke, C.D., Martin, V.J.J., Keasling, J.D. (2004) Tools for metabolic engineering in Escherichia coli. In: Baneyx, F., editor. Expression Technologies. U.K.: Horizon Scientific Press.