User:SukYeon Hwang
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Nathan SukYeon Hwang
PhD Candidate (Dr. Jennifer Elisseeff lab)
Department of Biomedical Engineering
Johns Hopkins School of Medicine
E-Mail : hwang@jhu.edu
Nathan's website
Research
Cartilage/bone tissue engineering
Microenvironment-mediated embryonic stem cell self-renewal and differentiation
Biomaterials-directed commitment and tissue formation of stem cells
Education and Professional Training
- Fall 2002- Present:
Johns Hopkins University School of Medicine, Baltimore, MD
PhD candidate, Department of Biomedical Engineering
Advisor: Jennifer Elisseeff, PhD - Fall 1998-May 2002:
Johns Hopkins University School of Engineering, Baltimore, MD (Class of 2002)
Biomedical Engineering (BME) with minor in Computer Science
Honors and Awards
- Student Award (January, 2006)
Award based on merit of paper presentation and content: The Society for Physical Regulation in Biology and Medicine (Jan, 2006) - Student Travel Award (January, 2006)
Travel award presented by the Society for Physical Regulation in Biology and Medicine 24th Scientific Conference. - Graduate Student Travel Award (June 2005)
Travel award presented by Graduate Student Association - Tau Beta Pi – Inducted as Junior class (2001)
Honor society invitation given to the top 8% of the engineering junior class based on academic merit. - Golden Key National Honor Society (2000)
Honor society invitation given to the top 15% of the class (120 out of 937) based on academic merit and involvement in community service. - Biomedical Engineering Honor Society (2001)
Honor society invitation given to top 20% BME majors based on academic merit. - Korean Scholar (2000)
Selected by Korean Embassy in Washington, D.C. based on academic merit. - Summer Undergraduate Research Fellowship at Southwestern Medical Center at Dallas (Summer 2000)
- PCUSA (Presbyterian Church of U.S.A) Scholarship (2000)
- Honorable Mention in Proposal to the 2002 Undergraduate Materials Research Initiative
- Honorable Mention in Proposal to the 2000 Undergraduate Materials Research Initiative
Publications
- Hwang, NS., Varghese, S., Zhang, Z., and Elisseeff, J. “Tissue Engineering Using Embryonic Stem Cells: Modulation of chondrogenesis by the extracellular microenvironment" (Advanced Drug Delivery Review, in preparation)
- Hwang, NS., Varghese, S., Zhang, Z., and Elisseeff, J. “Cartilage Tissue Engineering using Human ES-Derived Chondrocytes” (In Preparation)
- Hwang, NS., Varghese, S., Li, H., and Elisseeff, J. “Extracellular Microenvironment Regulation of Osteogenic and Chondrogenic Differentiation of Mesenchymal Stem Cells” Journal of Biomedical Materials Research (submitted)
- Varghese, S.*, Hwang, NS.* Ferran, A.*, ,Hilllel, A., Theprungsirkul, P., Zhang, Z., Shamblott, M., Gearhart, J., and Elisseeff, J. “Characterization and functional mesenchymal differentiation of human embryonic stem cells” Nature Biotechnology (In Revision, * Contributed equally to this work)
- Hwang, NS., Shyni Varghese, Lee, J., Zhang, Z., and Elisseeff, J. “Biomaterials-Directed In Vivo Commitment of Mesenchymal Cells Derived From Human Embryonic Stem Cells” FASEB Journal (Under Review)
- Capanzano, V., Hwang, NS., Moroni, L., Park, HB., Zhang, Z., Mizrahi, J., Seliktar, D., and Elisseeff, J. “Differential response of adult and embryonic M\mesenchymal progenitor cells to mechanical compression in hydrogels” Stem Cells (In Revision)
- Shyni Varghese, Hwang, NS., Canver, CA., Lin, D., Theprungsirikul, P., Elisseeff, J. ”Chondroitin sulfate based hydrogel niche for chondrogenic differentiation of mesenchmymal stem cells”, Matrix Biology (In press)
- Lee, H.J., Yu, C., Chansakul, T., Hwang, N.S., Varghese, S., and Elisseeff, J. “Enhanced chondrogenesis of mesenchymal stem cells in collagen mimetic peptide-modified microenvironment”, Matrix Biology (Under Review)
- Hwang, NS., Varghese, S., Lee, H. Janice, Theprungsirikul, P., Canver, A., Sharma, B., and Elisseeff, J.“Reponse of Zonal Chondrocytes in Extracellular Matrix-Hydrogels” FEBS Letters (In press)
- Hwang, NS., Varghese, S., Puleo C., Zhang, Z., and Elisseeff, J. “Morphogenetic Signals from Chondrocytes Promote Chondrogenic and Osteogenic Differentiation of Mesenchymal Stem Cells” Journal of Cellular Physiology (In Press)
- Varghese, S., Paranduangji, T., Sabani, S., Hwang, NS., Yarema, K., Elisseeff, J.“Glucosamine modulates chondrocyte proliferation, matrix synthesis, and gene expression”Osteoarthritis and Cartilage (In Press)
- Zhang, Z., Messana, J., Hwang, NS., Elisseeff J. “Reorganization of Actin Filaments Enhances Chondrogenic Differentiation of Cells Derived from Murine Embryonic Stem Cells” Biochemical and Biophysical Research Communication 2006 Sep 22;348(2):421-7
- Varghese S, Theprungsirikul P, Ferran A, Hwang NS, Elisseeff J H “Chondrogenic differentiation of human embryonic germ cell derived cells in hydrogels” EMB IEEE (In Press)
- Elisseeff J H, Ferran A, Hwang NS, Varghese S, Zhang Z. “The role of biomaterials in stem cell differentiation: Application in the musculoskeletal system” Stem Cells and Development 2006; 15(3): 295-303.
- Hwang, NS*., Varghese* S., Theprungsirikul, T., Canver, A., and Elisseeff, J. “Enhanced Chondrogenic Differentiation of Murine Embryonic Stem Cells in Hydrogels by Glucosamine Treatment” Biomaterials 2006; 27(36): 6015-23 (* Contributed equally to this work)
- Hwang, NS., Varghese, S., Zhang, Z., and Elisseeff, J. “Chondrogenic Differentiation of Human Embryonic Stem Cell-derived Cells in RGD-Modified Hydrogels” Tissue Engineering 2006; 12(9):2695-2706.
- Hwang, NS., Kim, M., Sampattavanich, S., Baek, J.H.,Zhang, Z., Elisseeff, J. “Effects of Three Dimensional Culture and Growth Factors on the Chondrogenic Differentiation of Murine Embryonic Stem Cells” Stem Cells 2006; 24(2):284-291.
- Kim, M.S., Hwang, NS., Lee, J., Kim, T.K., Shamblott, M., Gearhart, J., Elisseeff, J. (2005).“Musculoskeletal differentiation of Cells Derived from Human Embryonic Germ Cells”. Stem Cells 2005; 23(1):113-23.
Book Chapters
- Hwang, N., Varghese, S., and Elisseeff, J. “Cartilage Tissue Engineering: Directing Differentiation of Embryonic Stem Cells in Three-Dimensional Culture”, Humana Press: Methods in Molecular Biology-Stem Cell Assays (In Press)
- Lee, J., Varghese, S., Hwang, N., and Elisseeff, J. “Hydrogels for Cartilage Tissue Engineering: Modulation of Chondrogenesis by Extracellular Microenvironment”, Artech House Publishing Inc. Micro- and Nanoengineering of the Cell Microenvironment: Technologies and Applications (Submitted)