"Design": Difference between revisions
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<div style="padding: 10px; width: 730px; color: #3ca83c; background-color: #3ca83c"> | <div style="padding: 10px; width: 730px; color: #3ca83c; background-color: #3ca83c"> | ||
[[Image:MARIMOD3ca83c.png| 150px]] | [[Image:MARIMOD3ca83c.png| 150px]] | ||
[[Biomod/2013/Hokkaido | <font face="trebuchet ms" style="color:#FFFFFF" size="4"> '''Home''' </font>]] | [[Biomod/2013/Hokkaido | <font face="trebuchet ms" style="color:#FFFFFF" size="4"> '''Home''' | ||
[["What's "Marimo"?" | <font face="trebuchet ms" style="color:#FFFFFF" size="4"> '''What's | |||
</font>]] | |||
[["What's "Marimo"?" | <font face="trebuchet ms" style="color:#FFFFFF" size="4"> '''What's | |||
Marimo''' </font>]] | |||
| | ||
[["Design" | <font face="trebuchet ms" style="color:#FFFFFF" size="4"> '''Design''' | |||
</font>]] <br> | |||
[["Materials" | <font face="trebuchet ms" style="color:#FFFFFF" size="4"> '''Materials''' | |||
</font>]] | |||
[["Diary" | <font face="trebuchet ms" style="color:#FFFFFF" size="4"> '''Diary''' </font>]] | [["Diary" | <font face="trebuchet ms" style="color:#FFFFFF" size="4"> '''Diary''' </font>]] | ||
| | ||
[["People" | <font face="trebuchet ms" style="color:#FFFFFF" size="4"> '''People''' </font>]] | [["People" | <font face="trebuchet ms" style="color:#FFFFFF" size="4"> '''People''' | ||
</font>]] | |||
| | ||
[["Sponsors" | <font face="trebuchet ms" style="color:#FFFFFF" size="4"> '''Sponsors''' </font>]] | [["Sponsors" | <font face="trebuchet ms" style="color:#FFFFFF" size="4"> '''Sponsors''' | ||
</font>]] | |||
</div> | </div> | ||
===[[Image:タイトル○.png| 15px]] <font size="5">Background</font>=== | ===[[Image:タイトル○.png| 15px]] <font size="5">Background</font>=== | ||
---- | |||
<p> | <p> | ||
Biomolecular motor system such as microtubule-kinesin is an example of smallest natural machine<br> that can convert chemical energy obtained from ATP into mechanical work with high efficiency and<br> | Biomolecular motor system such as microtubule-kinesin is an example of smallest natural machine<br> | ||
that can convert chemical energy obtained from ATP into mechanical work with high efficiency | |||
and<br> | |||
specific power. Nowadays microtubule-kinesin system is being used as a building block for<br> | specific power. Nowadays microtubule-kinesin system is being used as a building block for<br> | ||
constructing micro-actuators and driving unit of the biodevices. To use as a building block,<br> | constructing micro-actuators and driving unit of the biodevices. To use as a building block,<br> | ||
dynamic self-organization of microtubule and kinesin into highly organized structures has been<br> | dynamic self-organization of microtubule and kinesin into highly organized structures has been<br> | ||
drawing much attention. Ring-shaped microtubule assemblies have been demonstrated to obtain through<br> | drawing much attention. Ring-shaped microtubule assemblies have been demonstrated to obtain | ||
through<br> | |||
dynamic self-organization. Considering the advantage of its geometry and handedness, they have<br> | dynamic self-organization. Considering the advantage of its geometry and handedness, they have<br> | ||
appeared to be a promising tool to harness continuous rotational motion without changing the<br> | appeared to be a promising tool to harness continuous rotational motion without changing the<br> | ||
| Line 29: | Line 44: | ||
</p> | </p> | ||
===[[Image:タイトル○.png| 15px]] Problem=== | |||
---- | |||
<p> | |||
Although ring-shaped microtubules possess immense potential with respect to their prospective <br> | |||
application in nanotechnology, several barriers needed to be surmounted yet as listed below.<br> | |||
</p> | |||
<p> | |||
<font size="3">No.1</font><br> | |||
In a closed system, consumption of energy spoils the potential activity of ring-shaped <br> | |||
microtubules. Supply of energy through ATP hydrolysis is a prerequisite to keep the ring-shaped<br> | |||
microtubules working continuously. Development of a system to provide energy continuously is <br> | |||
highly desired.<br> | |||
</p> | |||
<p> | |||
<font size="3">No.2</font><br> | |||
It is still unknown how much power we can harness from the rotational motion of the ring-shaped<br> | |||
microtubules. Once known, the power could be designed to use further in an appropriate way.<br> | |||
</p> | |||
<p> | |||
<font size="3">No.3</font><br> | |||
No system has been developed yet that can work by transmitting the power harnessed from<br> | |||
ring-shaped microtubules. This drawback is preventing integration or amplification of the power<br> | |||
of smallest natural machines.<br> | |||
</p> | |||
===[[Image:タイトル○.png| 15px]] | |||
===[[Image:タイトル○.png| 15px]] Solution=== | |||
---- | |||
<p> | |||
<font size="4">Solution for the problem 1</font><br> | |||
Ring-shaped microtubules are driven by kinesin where the energy comes from the hydrolysis<br> | |||
of ATP to ADP. A system that can use the ADP to reproduce ATP allow us to keep the ring-shaped<br> | |||
microtubules working continuously. To develop such a system, we synthesize micro gels <br> | |||
which contain F1/F0- ATPase together with photosystems. This gel is termed as “Marimo-Gel”.<br> | |||
The Marimo-Gel converts ADP to ATP by utilizing the energy from light. | |||
</p> | |||
<p> | |||
<font size="4">Solution for the problem 2</font><br> | |||
===[[Image:タイトル○.png| 15px]] | ===[[Image:タイトル○.png| 15px]] | ||
Revision as of 22:20, 30 August 2013
Background
Biomolecular motor system such as microtubule-kinesin is an example of smallest natural machine
that can convert chemical energy obtained from ATP into mechanical work with high efficiency
and
specific power. Nowadays microtubule-kinesin system is being used as a building block for
constructing micro-actuators and driving unit of the biodevices. To use as a building block,
dynamic self-organization of microtubule and kinesin into highly organized structures has been
drawing much attention. Ring-shaped microtubule assemblies have been demonstrated to obtain
through
dynamic self-organization. Considering the advantage of its geometry and handedness, they have
appeared to be a promising tool to harness continuous rotational motion without changing the
position of its mass center.
Problem
Although ring-shaped microtubules possess immense potential with respect to their prospective
application in nanotechnology, several barriers needed to be surmounted yet as listed below.
No.1
In a closed system, consumption of energy spoils the potential activity of ring-shaped
microtubules. Supply of energy through ATP hydrolysis is a prerequisite to keep the ring-shaped
microtubules working continuously. Development of a system to provide energy continuously is
highly desired.
No.2
It is still unknown how much power we can harness from the rotational motion of the ring-shaped
microtubules. Once known, the power could be designed to use further in an appropriate way.
No.3
No system has been developed yet that can work by transmitting the power harnessed from
ring-shaped microtubules. This drawback is preventing integration or amplification of the power
of smallest natural machines.
Solution
Solution for the problem 1
Ring-shaped microtubules are driven by kinesin where the energy comes from the hydrolysis
of ATP to ADP. A system that can use the ADP to reproduce ATP allow us to keep the ring-shaped
microtubules working continuously. To develop such a system, we synthesize micro gels
which contain F1/F0- ATPase together with photosystems. This gel is termed as “Marimo-Gel”.
The Marimo-Gel converts ADP to ATP by utilizing the energy from light.
Solution for the problem 2
===
