20.109(F09): KaWi's Final Project: Difference between revisions

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Topics (in brief):
Topics (in brief):
Riboswitches to reg transcription.
Riboswitches to reg transcription.
PPAR-delta expression in macrophages recognize apoptotic cells.
PPAR-delta expression in macrophages recognize apoptotic cells.
Exit from mitosis into interphase through Sic1.
Exit from mitosis into interphase through Sic1.
Amino Acid Mutations leading to human speech
Amino Acid Mutations leading to human speech
'Ribosome Rescue'--pausing and restarting Ribosomes during translation
'Ribosome Rescue'--pausing and restarting Ribosomes during translation


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Cancer cells:  
Cancer cells:  
Tools: HIV has integrase, protease, reverse transcriptase.  Specific to HIV cells, distinguishing it from normal cells.
Tools:  
HIV has integrase, protease, reverse transcriptase that are specific to HIV cells, distinguishing it from normal cells.
 
Ribosomes can be paused or restarted using releasing factors, tmRNA*SNPB.
Ribosomes can be paused or restarted using releasing factors, tmRNA*SNPB.
PPAR displayed on the surface of apoptotic cells trigger clearance by macrophages. --> how to make cancer cells express PPAR.
 
How to make cancer cells trigger PPAR expression in macrophages. Or display receptors that bind to PPAR protein.





Revision as of 22:20, 18 November 2009


Topics (in brief): Riboswitches to reg transcription.

PPAR-delta expression in macrophages recognize apoptotic cells.

Exit from mitosis into interphase through Sic1.

Amino Acid Mutations leading to human speech

'Ribosome Rescue'--pausing and restarting Ribosomes during translation



Cancer cells: Tools: HIV has integrase, protease, reverse transcriptase that are specific to HIV cells, distinguishing it from normal cells.

Ribosomes can be paused or restarted using releasing factors, tmRNA*SNPB.

How to make cancer cells trigger PPAR expression in macrophages. Or display receptors that bind to PPAR protein.



Possible idea 1: See how Ribosome Rescue paper's (pausing or restarting ribosomes) mechanism affects cancer cells. If one extreme or the other causes apoptosis.




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