20.109(F12) Pre-Proposal: Viral mitigation of insulin resistance

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Investigators

  • Stanley Gill
  • Amy Liu
  • T/R 20.109 Lab
  • Team Yellow

Title of Proposed Project

Regulating Resistin Levels through a Synthetic Circuit Injected via Vector Immunoprophylaxis

Project Summary

One of the hallmark characteristics of obesity and Type 2 diabetes is insulin resistance. Resistin, a peptide produced by endocrine adipocytes in mice, has been implicated in increasing the likelihood of insulin resistance and is present in high levels in the blood of obese patients. Here, we explore that the introduction of a regulated synthetic system that produces antibodies against resistin may stave off insulin resistance, alleviating and preventing the development of Type 2 diabetes.

Introduction

ONE PARAGRAPH and at least TWO REFERENCES

  • What is known about this field
  • Why is this field important

Your idea

Personal health is of great concern to today's society, especially in relation to weight loss. Alongside the rate of obesity growing in today's society, a lot

A sketch

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