20.949/F10:Schedule

Lecture schedule 1. September 9: Overview of Synthetic Biology 2. September 14: Biophysical Models of Basic Biological Processes I 3. September 16: Biophysical Models of Basic Biological Processes II 4. September 21: Noise propagation and regulatory feedback 5. September 23: Computational modeling of genetic circuits (ODE, stochastic, Lambda) 6. September 28: Dynamics of Biological Circuits -- Feed-forward motifs 7. September 30: Dynamics of Biological Circuits -- Toggle switches and bistability 8. September 30: Dynamics of Biological Circuits -- Oscillators 10. October 5: Dynamics of Biological Circuits -- Bifurcation analysis / phase space 11. October 7: Cell-cell communication I 11. October 12: Cell-cell communication II 12. October 14: RNA regulation (bacterial / microbial) 13. October 19: RNA regulation (Eukarytoic) 14. October 21: Protein tagging: secretion / localization / degradation 15. October 26: Protein engineering (modular design of proteins) to explore functional 16. October 28: Protein-protein interaction networks 17. November 2: Metabolic engineering 18. November 4: Interfacing to other cell functions 19. November 9: Principles of design -- from parts to modules to systems I 20. November 11: Principles of design -- from parts to modules to systems II 21. November 16: Principles of design -- from parts to modules to systems III 22. November 18: Principles of design -- from parts to modules to systems IV 23. November 23: Directed evolution (parts & circuits) 24. November 30: History of DNA manipulation 25. December 2: Advanced DNA design & cloning 26. December 7: Synthetic biology applications 27. December 9: Synthetic Life / Perspectives & challenges 28. December X-Y: Term project presentations