2020(S09) Lecture:week 1: Difference between revisions
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=='''Homework''' for tomorrow's studio session== | =='''Homework''' for tomorrow's studio session== | ||
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'''Note''' that this team developed a tremendously useful website that describes both their project, their human practice work and the basic background a person might need to understand the work. If your molecular biology is rusty, you can refresh your memory [http://2008.igem.org/Team:Heidelberg/Human_Practice/Phips_the_Phage/General_Backround| here] | '''Note''' that this team developed a tremendously useful website that describes both their project, their human practice work and the basic background a person might need to understand the work. If your molecular biology is rusty, you can refresh your memory [http://2008.igem.org/Team:Heidelberg/Human_Practice/Phips_the_Phage/General_Backround| here] | ||
===Our second feature presentation=== | ===Our second feature presentation=== | ||
Our second featured presentation will emphasize some of the "engineering" that can be accomplished in | Our second featured presentation will emphasize some of the "engineering" that can be accomplished in a summer by a talented group of undergrads much like yourselves. We'll listen to | ||
* the 2006 iGEM team from MIT describing fine chemical synthesis [http://www.igem2006.com/presentations.htm presentation video] [[Media:IGEM2006-MIT-Powerpoint.ppt| presentation ppt]] <br> | * the 2006 iGEM team from MIT describing a neat project for fine chemical synthesis [http://www.igem2006.com/presentations.htm presentation video] [[Media:IGEM2006-MIT-Powerpoint.ppt| presentation ppt]] <br> | ||
Their project will allow us to focus on | Their project will allow us to focus on | ||
** programming genetic logic | ** '''programming genetic logic, growth phases of bacterial cultures, ethical questions of human experimentation''' | ||
***our ppt review of these processes is [[ | here]] | |||
===After each presentation=== | ===After each presentation=== | ||
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*what areas were tackled? | *what areas were tackled? | ||
*how many also proposed solutions to these problems? | *how many also proposed solutions to these problems? | ||
After we've all discussed the letter, you'll have a chance to hear from the other groups. Be sure to take notes on your letter about any new ideas, clarifications, or thoughts you have from the discussion. You will turn in a revised letter before tomorrow. | |||
=='''Homework''' for tomorrow's challenge session== | =='''Homework''' for tomorrow's challenge session== | ||
1. To solidify the biology and engineering that's associated with the two projects we studied today, please look at the documentation of their project ([http://2008.igem.org/Team:Heidelberg here for Heidelberg 2008] and [http://openwetware.org/wiki/IGEM:MIT/2006 here for MIT 2006]) and answer the following questions: | |||
*The Heidelberg team built two chimeric receptors to drive chemotaxis in response to AI-2. What successes did they realize? What experiment didn't work? What will they try next? | |||
*The lambda phage built by the Heidelberg team had both a selectable drug marker (CamR) and an origin to enable the phage to transfer via the F pilus (oriT). However the phage wasn't able to lyse either the predator strain it resided in, or the prey strains it infected. Why (you'll have 2 different answers here)? | |||
When you are finished, please upload your assignment to your "Personal Design Portfolio" in the [http://openwetware.org/wiki/Special:DropBox the homework dropbox.], calling your assignment: FirstInitial_LastName_PDP_1.doc, for example: <font color = red> B_Obama_PDP_1.doc </font color><br> | |||
'''Time to complete this letter revision and answer these questions: 1 hour MAX.'''< | 2. You should revise your letter based on any feedback you received from your classmates today. When you are finished, please upload your letter to your "Personal Design Portfolio" in the [http://openwetware.org/wiki/Special:DropBox the homework dropbox.], calling your assignment: FirstInitial_LastName_PDP_2.doc, for example: <font color = red>B_Obama_PDP_2.doc</font color> <br><center> | ||
'''Time to complete this letter revision and answer these questions: 1 hour MAX.'''</center> | |||
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Revision as of 09:52, 30 December 2008
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| Home | Lecture and Studio schedule |
20.902 Reading Schedule | |
| Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 | |||
| Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14 | |||
| Expectations | Guidelines: 3 Ideas Presentation | Guidelines: Tech Spec Review | Guidelines: Final Presentations |
| Team Building Resources | Teacher Resources |
Week 1 Tuesday
Challenge: Project Runway
Instructions: Today you will design, build (i.e. fold) and launch a paper airplane. Your goal is to make a plane that flies further than anyones. Working in teams of 3, choose one person to be the designer, one to be the builder, and one to be the launcher. You can talk to each other at all stages but be sure each person does the assigned job and that someone takes notes of your work together (decisions, uncertainties, disagreements, expertise etc). Your team may use the internet if you want. The designer has one dollar to spend and your team must keep track of costs. No refunds will be issued for parts you do not use. In the event of a tie, cost and aesthetics will serve as the tie breaker. Relevant materials cost:
- paper is 30 cents a sheet
- paper clips are 10 cents each
- scotch tape is 5 cents per 1 inch strip
- pennies cost 20 cents each
- a pencil costs 10 cents
- scissors are unavailable
- a test flight before the competition costs 30 cents.
Your team has 20 minutes to design and build a plane for the competition. If you are not ready to launch at this time, you will forfeit.
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Once "project runway" has launched and the winning design team has been recognized, we'll work as a class to add more ideas, questions and thoughts to this list.
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Homework for tomorrow's studio session
Draft a letter. Address this letter to someone(s) you care about. Your letter should introduce and describe a real world problem or opportunity, one that you have inherited, identified, dreamed about, or otherwise encountered, and that you would like to solve or realize. Your letter should explain why you feel the problem or opportunity is important, and what the consequences of success might be. You can focus on more than one issue, but each issue needs to be explained. Please print and bring your letter to the studio tomorrow. Time to complete this letter: 1 hour MAX.
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We're looking ahead to the project you and your team will design this term...the first step is for you to decide what you'd like to work on. This letter should start you thinking about your areas of interest. The letter will also be a way to talk with others about things that interest them. Maybe you'll hear an idea you never considered and want to investigate it further. Maybe you'll find someone with very similar concerns. |
Week 1 Studio
Part 1: Wednesday matinee
Instructions: Today you will have the opportunity to watch two videos showcasing completed iGEM projects. "iGEM" stands for the "international Genetically Engineered Machines" competition. It is a summer-long opportunity for teams of students working at colleges and universities around the world to design and build genetically engineered machines, many of which use standard biological parts from the Registry of Standard Biological Parts. The videos will orient you to the kinds of accomplishments realized in a summer by teams of undergraduates and their advisers.
Our first feature presentation
Our first featured presentation will emphasize some of the "biology" that's often present in "synthetic biology." As a class we'll watch:
- the 2008 iGEM team from Heidelberg describing a genetically-engineered bacteria that will find, and kill pathogenic bacteria presentation video presentation ppt
In watching their project we can focus on
Note that this team developed a tremendously useful website that describes both their project, their human practice work and the basic background a person might need to understand the work. If your molecular biology is rusty, you can refresh your memory here
Our second feature presentation
Our second featured presentation will emphasize some of the "engineering" that can be accomplished in a summer by a talented group of undergrads much like yourselves. We'll listen to
- the 2006 iGEM team from MIT describing a neat project for fine chemical synthesis presentation video presentation ppt
Their project will allow us to focus on
- programming genetic logic, growth phases of bacterial cultures, ethical questions of human experimentation
- our ppt review of these processes is [[ | here]]
- programming genetic logic, growth phases of bacterial cultures, ethical questions of human experimentation
After each presentation
You will have 10 minutes to gather with your fellow moviegoers and discuss what you saw, using these "iGEM review questions" as a guide for your conversations:
- what was the problem this team chose to address and why?
- is this an important problem and why or why not?
- did they succeed in part or in total?
- are there aspects of the work that are unclear to you?
- if you could ask this team one question what would it be?
Part 2: Dear John
As homework you were asked to draft a letter describing a real world problem or opportunity you have inherited that could be addressed in the near term. You should discuss these letters at your team tables and make some notes about them on the white boards. For example,
- who were they addressed to?
- how many problems/opportunities did each letter address?
- what areas were tackled?
- how many also proposed solutions to these problems?
After we've all discussed the letter, you'll have a chance to hear from the other groups. Be sure to take notes on your letter about any new ideas, clarifications, or thoughts you have from the discussion. You will turn in a revised letter before tomorrow.
Homework for tomorrow's challenge session
1. To solidify the biology and engineering that's associated with the two projects we studied today, please look at the documentation of their project (here for Heidelberg 2008 and here for MIT 2006) and answer the following questions:
- The Heidelberg team built two chimeric receptors to drive chemotaxis in response to AI-2. What successes did they realize? What experiment didn't work? What will they try next?
- The lambda phage built by the Heidelberg team had both a selectable drug marker (CamR) and an origin to enable the phage to transfer via the F pilus (oriT). However the phage wasn't able to lyse either the predator strain it resided in, or the prey strains it infected. Why (you'll have 2 different answers here)?
When you are finished, please upload your assignment to your "Personal Design Portfolio" in the the homework dropbox., calling your assignment: FirstInitial_LastName_PDP_1.doc, for example: B_Obama_PDP_1.doc
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Most of our studio session today was spent considering two projects carried out by undergraduates not unlike yourself. They worked in teams (as you will) to figure out what they wanted to build (as you will) and then spent some time in the lab realizing their project (not possible in this class but you could join the iGEM program this summer, as three of the 20.020 students from Spring 2008 did!). Remember that these are just two projects of many and you should feel motivated by them to work this term on a project that's important to you. |
Week 1 Thursday
Challenge: Sexy on the inside 2
- Watch this video in which Gever Tulley talks about learning by doing.
- Watch this video of a person taking apart a MacBook Air
- Working in groups of 4, you will take apart a tape recorder. One person should work the tools, another should record the process (e.g. "began by taking off back panel), another should keep a parts list (e.g. "4 Phillips-screws 3 mm long from back panel"), and the last person should record the purpose of each component (e.g. "Phillips screws held back panel in place). Your team's goal is to disassemble the tape recorder into the greatest number of re-usable parts... note of the word "reusable" since next time we meet, the goal will be to reassemble your tape recorder into a working machine. As you work, you may find it helpful to describe what you think each component does and if it's made of sub-components that can be separated further without forever destroying the component's function.
- "One of the problems of taking things apart and seeing how they work--supposing you're trying to find out how a cat works--you take that cat apart to see how it works, what you've got in your hands is a non-working cat," Douglas Adams
- If there's time, watch this video showing the inner life of the cell, an understanding largely achieved by scientific "take apart" techniques.
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Taking something apart is one way to understand how it works. Having disassembled a simple machine, you should consider what you've gained from the process. What did you learn? What about this challenge resembled science and what did or didn't feel like engineering? Was the tape player build to enable this sort of work? What (else) has the tape player been built for/ optimized for? What are the chances you'll be able to re-assemble this machine next week? Before leaving class today we'll add ideas/questions/thoughts to this list.
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Homework for next week's challenge session
- Read Adventures in SB. Using the problem or opportunity you described in your letter, draft a two chapter script for a comic book using characters from your imagination. In chapter 1, have the characters talk about the problem or opportunity. In chapter 2, have the characters brainstorm a way to solve the issue. Print these out to bring to the 20.020 challenge time next Tuesday. Time to complete this script: 1 hour MAX.
- For an example script, and making a comic background, check this out.
- Complete survey. Click here to start It should only take ~10 minutes. Please note that this is NOT the same survey that the Project-Based Learning Center might have asked you to complete.
