7.342:Materials: Difference between revisions
No edit summary |
Mattguenther (talk | contribs) No edit summary |
||
Line 47: | Line 47: | ||
Taunton, J., Hassig, C. A., and Schreiber, S. L. (1996). Science 272, 408-411. | Taunton, J., Hassig, C. A., and Schreiber, S. L. (1996). Science 272, 408-411. | ||
==Week 4: Methylation and the Emergence of the "Histone Code"== | |||
==Papers== | |||
'''[http://www.nature.com/nature/journal/v410/n6824/pdf/410116a0.pdf Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.]''' | |||
Lachner, M., O'Carroll, D., Rea, S., Mechtler, K., and Jenuwein, T. (2001). Nature 410, 116-120. | |||
'''[http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WSN-4GDJB3K-9-K&_cdi=7051&_user=501045&_coverDate=06%2F17%2F2005&_sk=%23TOC%237051%232005%23998789993%23599046%23FLA%23display%23Volume_121,_Issue_6,_Pages_811-962_(17_June_2005)%23tagged%23Volume%23first%3D121%23Issue%23first%3D6%23date%23(17_June_2005)%23&view=c&_gw=y&wchp=dGLbVlz-zSkzS&md5=d443190870a7f27ceded81ae5653904e&ie=/sdarticle.pdf WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development.]''' | |||
Wysocka, J., Swigut, T., Milne, T. A., Dou, Y., Zhang, X., Burlingame, A. L., Roeder, R. G., Brivanlou, A. H., and Allis, C. D. (2005). Cell 121, 859-872. |
Revision as of 13:39, 24 September 2006
Week 1: Introduction
Week 2: Chromatin Functions to Define Cell State
Papers
Chromosomal Subunits in Active Genes Have an Altered Conformation
Weintraub, H & Groudine, M. (1976) Science 193, 848-856.
Hyperdynamic Plasticity of Chromatin Proteins in Pluripotent Embryonic Stem Cells
Meshorer, E, Yellajoshula, D, George, E, Scambler, PJ, Brown, DT, & Misteli, T. (2006) Dev Cell 10, 105-116.
Bonus Materials
Commentary on Meshorer et al paper
Supplemental Data for Meshorer et al paper
Obituary for Harold Weintraub from Molecular Biology of the Cell, 1995 (by Marc Kirschner)
Obituary for Harold Weintraub from Cell, 1995 (by Richard Axel & Tom Maniatis)
Week 3: Chromatin Structure and Discovery of Chromatin Modifying Enzymes
Papers
Brownell, J. E., Zhou, J., Ranalli, T., Kobayashi, R., Edmondson, D. G., Roth, S. Y., and Allis, C. D. (1996). Cell 84, 843-851.
A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p.
Taunton, J., Hassig, C. A., and Schreiber, S. L. (1996). Science 272, 408-411.
Week 4: Methylation and the Emergence of the "Histone Code"
Papers
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.
Lachner, M., O'Carroll, D., Rea, S., Mechtler, K., and Jenuwein, T. (2001). Nature 410, 116-120.
Wysocka, J., Swigut, T., Milne, T. A., Dou, Y., Zhang, X., Burlingame, A. L., Roeder, R. G., Brivanlou, A. H., and Allis, C. D. (2005). Cell 121, 859-872.