7.342:Materials

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7.342: Reading the Blueprint of Life: Transcription, Stem Cells, & Differentiation

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Contents

Week 1: Introduction

Course Syllabus Image:Syllabus v4.doc


Week 2: Chromatin Functions to Define Cell State

Papers

Chromosomal Subunits in Active Genes Have an Altered Conformation

Weintraub, H & Groudine, M. (1976) Science 193, 848-856.


"Hyperdynamic Plasticity of Chromatin Proteins in Pluripotent Embryonic Stem Cells"

Meshorer, E, Yellajoshula, D, George, E, Scambler, PJ, Brown, DT, & Misteli, T. (2006) Dev Cell 10, 105-116.

Bonus Materials

"Commentary on Meshorer et al paper"

"Obituary for Harold Weintraub from Molecular Biology of the Cell, 1995 (by Marc Kirschner)"

"Obituary for Harold Weintraub from Cell, 1995 (by Richard Axel & Tom Maniatis)"
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