Alcazar

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'''''Genetics & Evolution of Plant-Environment Interactions'''''<br><br>
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'''''Plant-Environment Interactions and <br>Molecular Pharming'''''<br><br>
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Our lab studies the genetic and molecular bases for the adaptation of plants to their local environments. We mainly focus on the adaptation to stress (abiotic and biotic) exploring the natural variation present in wild populations.
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Our lab studies the genetic and molecular bases for the adaptation of plants to their local environments. We mainly focus on the adaptation to stress (abiotic and biotic) and how this can be translated in an efficient molecular pharming (production of pharmaceutical compounds in plants) under the current challenges of climate change.
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'''Evolution of NB-LRR genes and pathogens ''' <br>
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Current projects <br><br>
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'''Disease resistance in plants ''' <br>
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We're currently studying the evolution of NB-LRR immune-receptor genes in nature that condition defense against evolving pathogens and how this derives in immune-driven reproductive isolation barriers within species (hybrid incompatibilities). We're particularly studying the evolution of the RPP1-like cluster, which is involved in recognition of the naturally occurring ''Arabidopsis thaliana'' pathogen ''Hyaloperonospora arabidopsidis'' and frequently involved in hybrid incompatibility. Through a combined research involving molecular biology,  population genetics and biochemical approaches, we study plant-pathogen coevolution in wild Arabidopsis populations and how this is translated into the genetic composition of NB-LRR genes in local populations. <br><br>  
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We're currently studying the evolution of ''NB-LRR'' immune-receptor genes and other interacting loci that condition defense against evolving pathogens and how this derives in immune-related hybrid incompatibility, an important obstacle in plant breeding. We address these questions using molecular biology, population genetics and biochemical approaches. This research is complemented by the study of the modulation of ''NB-LRR'' signaling by temperature which is important under the current climate change predictions.  <br><br>
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'''Natural variation of stress-induced metabolites''' <br>
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We study the genetic bases for the naturally occurring  variation of some stress metabolites involved in resistance traits to abiotic and biotic stresses in collaboration with different laboratories. We identify natural compounds which protect plants from stress. Through molecular approaches we improve the resistance of plants to different stresses. <br>
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'''Molecular pharming''' <br>
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We produce proteins of pharmaceutical interest in plants and study ways to improve their productivity under different environments to adapt to the requirements of local climates.
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For a more detailed view of our research, have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. <br> For general public information have a look at [http://alcazar.openwetware.org/Alcazar_Youtube.html +info]. <br><br>
For a more detailed view of our research, have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. <br> For general public information have a look at [http://alcazar.openwetware.org/Alcazar_Youtube.html +info]. <br><br>
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[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
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'''JOB OFFERS''' <br>
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''' '''Would you like to work with us? '''您想与我们一起工作吗?''' ''¿Quieres trabajar con nosotros?''''' <br>'''
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'''NEW'''
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Interested students should contact us by e-mail.
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A 3-years PhD position (2015-2017) is available in our laboratory to study
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'''有兴趣的同学通过电子邮件联系我们'''
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Arabidopsis ''NB-LRR'' evolution and interactions with ''Hyaloperonospora arabidopsidis'' pathogens.
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''Contacta con nosotros por e-mail.''
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[mailto:ralcazar@ub.edu Contact ALCAZAR LAB]
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Interested candidates should send us their CV and two letters of reference by e-mail.
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Questions should be addressed to the same e-mail address below.
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Application period: 1 July - 15 September 2014
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Expected starting date: January 2015
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[mailto:ralcazar@ub.edu Contact]
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Follow Alcazar Lab press releases at EduBlogs: [[http://ralcazar.edublogs.org/ here]]
 
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'''The Roles of Polyamines during the lifespan of plants:from development to stress'''(2014).
 
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Tiburcio AF, Altabella T, Bitrián M and Alcázar R. Planta, doi: 10.1007/s00425-014-2055-9.
 
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online first March 2014 [http://link.springer.com/article/10.1007/s00425-014-2055-9 read here]
 
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'''LATEST PUBLICATIONS''' <br>
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Editorial article of upcoming e-book in Frontiers in Plant Science. Editors: Ruben Alcazar & A.F. Tiburcio.
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[http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00319/full Plant polyamines in stress and development: an emerging area of research in plant sciences] <br>
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[http://link.springer.com/article/10.1007/s00425-014-2055-9 '''The Roles of Polyamines during the lifespan of plants:from development to stress''']
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Tiburcio AF, Altabella T, Bitrián M and Alcázar R. (2014) Planta 240: 1-18.<br>
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'''More news'''
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<br>
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Ruben Alcazar Lab granted by the Spanish Programme of Scientific and Technical Excellence 2014.
   
   

Current revision



University of Barcelona
Barcelona Campus of Knowledge
Barcelona, Spain
Contact
alcazar.openwetware.org--thumb.jpg


Plant-Environment Interactions and
Molecular Pharming


Our lab studies the genetic and molecular bases for the adaptation of plants to their local environments. We mainly focus on the adaptation to stress (abiotic and biotic) and how this can be translated in an efficient molecular pharming (production of pharmaceutical compounds in plants) under the current challenges of climate change.



Current projects

Disease resistance in plants

We're currently studying the evolution of NB-LRR immune-receptor genes and other interacting loci that condition defense against evolving pathogens and how this derives in immune-related hybrid incompatibility, an important obstacle in plant breeding. We address these questions using molecular biology, population genetics and biochemical approaches. This research is complemented by the study of the modulation of NB-LRR signaling by temperature which is important under the current climate change predictions.


Natural variation of stress-induced metabolites

We study the genetic bases for the naturally occurring variation of some stress metabolites involved in resistance traits to abiotic and biotic stresses in collaboration with different laboratories. We identify natural compounds which protect plants from stress. Through molecular approaches we improve the resistance of plants to different stresses.

Molecular pharming

We produce proteins of pharmaceutical interest in plants and study ways to improve their productivity under different environments to adapt to the requirements of local climates.


For a more detailed view of our research, have a look at our Research Projects and Scientific Publications sections.
For general public information have a look at +info.


News and Announcements e-Board

JOB OFFERS

NEW
A 3-years PhD position (2015-2017) is available in our laboratory to study 
Arabidopsis NB-LRR evolution and interactions with Hyaloperonospora arabidopsidis pathogens.

Interested candidates should send us their CV and two letters of reference by e-mail.

Questions should be addressed to the same e-mail address below.

Application period: 1 July - 15 September 2014

Expected starting date: January 2015

Contact



LATEST PUBLICATIONS

Editorial article of upcoming e-book in Frontiers in Plant Science. Editors: Ruben Alcazar & A.F. Tiburcio.
Plant polyamines in stress and development: an emerging area of research in plant sciences 
The Roles of Polyamines during the lifespan of plants:from development to stress
Tiburcio AF, Altabella T, Bitrián M and Alcázar R. (2014) Planta 240: 1-18.

More news

Ruben Alcazar Lab granted by the Spanish Programme of Scientific and Technical Excellence 2014.





The Faculty | The University | The Campus | Scientific and Technological Centers




Full address: Facultat de Farmacia, Universitat de Barcelona, Unitat de Fisiologia Vegetal. Avda Joan XXIII 27-31, 08028 Barcelona (Spain).
Tel +34 934 024 492 Fax +34 934 029 043

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