Alcazar

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'''''Dear visitor,'''''<br>
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<br> Welcome to the Molecular Genetics of Plant Stress Tolerance Lab (Ruben Alcazar) ''' at the Department of Biology, Healthcare & Environment of the University of Barcelona. <br><br>
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We're a recently created research group that investigates the '''adaptation of plants to local environments'''. We focus on the evolutionary adaptation of plant populations to '''abiotic and biotic stresses''', which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.<br>
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For a more detailed view of our research, please have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.<br><br>
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Info currently available in the following languages: <br>
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[[http://alcazar.openwetware.org EN]] [[http://alcazar_cat.openwetware.org CAT]] [[http://alcazar_es.openwetware.org ES]]
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<br><br><br><br><br><br><br><br>
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'''''Genetics & Evolution of Plant-Environment Interactions'''''<br><br>
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'''1. MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS (R.Alcázar)''' <br>
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Our lab studies the genetic and molecular bases for the adaptation of plants to their local environments. We mainly focus on the adaptation to stress (abiotic and biotic) exploring the natural variation present in wild populations.
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In our lab, we make use of the extensive natural variation of [https://en.wikipedia.org/wiki/Arabidopsis_thaliana ''Arabidopsis thaliana''] populations to answer key fundamental questions:
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* '''How plants adapt to local environments including the microbiota?'''
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* '''How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?'''
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* '''How the environment manipulates immune responses? How this affects the above points?'''
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'''Evolution of NB-LRR genes and pathogens ''' <br>
 
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We're currently studying the evolution of NB-LRR immune-receptor genes in nature that condition defense against evolving pathogens and how this derives in immune-driven reproductive isolation barriers within species (hybrid incompatibilities). We're particularly studying the evolution of the RPP1-like cluster, which is involved in recognition of the naturally occurring ''Arabidopsis thaliana'' pathogen ''Hyaloperonospora arabidopsidis'' and frequently involved in hybrid incompatibility. Through a combined research involving molecular biology,  population genetics and biochemical approaches, we study plant-pathogen coevolution in wild Arabidopsis populations and how this is translated into the genetic composition of NB-LRR genes in local populations. <br><br>
 
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For a more detailed view of our research, have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. <br> For general public information have a look at [http://alcazar.openwetware.org/Alcazar_Youtube.html +info]. <br><br>
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To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of ''Arabidopsis'' immune-related incompatible hybrids. These are hybrids obtained by crosses of natural ''Arabidopsis'' accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.
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These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.
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[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
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''' '''Would you like to work with us? '''您想与我们一起工作吗?''' ''¿Quieres trabajar con nosotros?''''' <br>'''
 
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Interested students should contact us by e-mail.
 
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'''有兴趣的同学通过电子邮件联系我们'''
 
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''Contacta con nosotros por e-mail.''
 
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[mailto:ralcazar@ub.edu Contact ALCAZAR LAB]
 
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Follow Alcazar Lab press releases at EduBlogs: [[http://ralcazar.edublogs.org/ here]]
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Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.  
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'''The Roles of Polyamines during the lifespan of plants:from development to stress'''(2014).
 
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Tiburcio AF, Altabella T, Bitrián M and Alcázar R. Planta, doi: 10.1007/s00425-014-2055-9.
 
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online first March 2014 [http://link.springer.com/article/10.1007/s00425-014-2055-9 read here]
 
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Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.
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<br><br>
 
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[http://www.ub.edu/farmacia/ The Faculty] | [http://www.ub.edu The University] | [http://bkc.upc.ub.edu/ The Campus] | [http://www.ccit.ub.edu/EN/home.html Scientific and Technological Centers]
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<br>
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'''2. Polyamines and plant stress protection (R. Alcázar and Antonio F. Tiburcio)'''
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Polyamines are small amines present in living organisms. Polyamines are essential for cell viability and have co-evolved and participate in developmental and stress signalling pathways. We’re interested to know how polyamines exert their functions in plants, with a focus on stress tolerance. For this, we’re applying modern genetics, genomics and evolutionary biology. Our final goal is to provide new strategies for crop protection against different types of stress. Read our latest publication  on this topic [http://onlinelibrary.wiley.com/doi/10.1111/pce.12714/abstract here]. Most cited review (>450 times) [http://link.springer.com/article/10.1007%2Fs00425-010-1130-0?LI=true here]
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<font face="helvetica" style="color:#000000" font size="3">
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[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
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  NEWS
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''' ACADEMIC PRESS RELEASES'''<br>
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[http://www.ub.edu/web/ub/en/menu_eines/noticies/2015/01/020.html? Alcázar Lab work highlighted by the University of Barcelona 20.01.15]<br>
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[http://www.ub.edu/noticies/cgi/event.pl?id=62490&noticiaub=FARMACIA Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015]<br>
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[http://sefv.net/files/sd_publicaciones/58.pdf Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015]<br>
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[http://www.mpipz.mpg.de/4042700/PM_Parker_2015 PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.]<br>
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[http://www.ub.edu/web/ub/en/menu_eines/noticies/2013/11/063.html? Arabidopsis semidwarfs: the green revolution in nature] 02.12.2013. University of Barcelona.<br>
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[http://www.mpipz.mpg.de/5389/news_publication_619091 Hybrid plants with over-reactive immune system] 17.11.2010. Max Planck Society.
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Full address: Facultat de Farmacia, Universitat de Barcelona, Unitat de Fisiologia Vegetal. Avda Joan XXIII 27-31, 08028 Barcelona (Spain). <br>
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Rubén Alcázar is Ramón y Cajal Researcher at the Department of Biology, Healthcare and Environment of the [http://www.ub.edu University of Barcelona].<br>
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Tel +34 934 024 492 Fax +34 934 029 043 <br><br>
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<p>This wiki site is built under [http://www.openwetware.org Openwetware], an open access movement promoting the sharing of information among researchers.</p>
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<br>'''Research in Alcázar Lab is supported by:'''
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* 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
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* Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
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* BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).
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Current revision




Dept. Biology, Healthcare & Environment
Section of Plant Physiology
Facultat de Farmàcia, Av. Joan XXIII 27-31
08028 Barcelona, Spain

Map


Dear visitor,

Welcome to the Molecular Genetics of Plant Stress Tolerance Lab (Ruben Alcazar) at the Department of Biology, Healthcare & Environment of the University of Barcelona.

We're a recently created research group that investigates the adaptation of plants to local environments. We focus on the evolutionary adaptation of plant populations to abiotic and biotic stresses, which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.

For a more detailed view of our research, please have a look at our Research Projects and Scientific Publications sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.

Info currently available in the following languages:
[EN] [CAT] [ES]










1. MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS (R.Alcázar)


In our lab, we make use of the extensive natural variation of Arabidopsis thaliana populations to answer key fundamental questions:

  • How plants adapt to local environments including the microbiota?
  • How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?
  • How the environment manipulates immune responses? How this affects the above points?


To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of Arabidopsis immune-related incompatible hybrids. These are hybrids obtained by crosses of natural Arabidopsis accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.


These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.


Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.


Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.




2. Polyamines and plant stress protection (R. Alcázar and Antonio F. Tiburcio)

Polyamines are small amines present in living organisms. Polyamines are essential for cell viability and have co-evolved and participate in developmental and stress signalling pathways. We’re interested to know how polyamines exert their functions in plants, with a focus on stress tolerance. For this, we’re applying modern genetics, genomics and evolutionary biology. Our final goal is to provide new strategies for crop protection against different types of stress. Read our latest publication on this topic here. Most cited review (>450 times) here



News and Announcements e-Board

 NEWS

ACADEMIC PRESS RELEASES

Alcázar Lab work highlighted by the University of Barcelona 20.01.15
Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015
Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015
PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.
Arabidopsis semidwarfs: the green revolution in nature 02.12.2013. University of Barcelona.
Hybrid plants with over-reactive immune system 17.11.2010. Max Planck Society.



Rubén Alcázar is Ramón y Cajal Researcher at the Department of Biology, Healthcare and Environment of the University of Barcelona.



Research in Alcázar Lab is supported by:


  • 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
  • Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
  • BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).

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