Alcazar:Research

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Research - Línies de Recerca - Líneas de Investigación
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Research projects- Projectes de Recerca - Proyectos de Investigación
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Revision as of 04:02, 4 August 2013

Research projects- Projectes de Recerca - Proyectos de Investigación


Faculty of Pharmacy
University of Barcelona (UB)
Department of Natural Products,
Plant Biology and Soil Science.
Av. Joan XXIII s/n
08028 Barcelona

alcazar.openwetware.org--thumb.jpg


GENETICS OF TEMPERATURE MODULATION OF PLANT IMMUNITY (DISEASENVIRON)
Funded under 7th Framework Programme
European Union
Research area:FP7-PEOPLE-2011-CIG Marie-Curie Action
Career Integration Grants
Grant holder: Ruben Alcazar

Summary

During their life cycle, plants are exposed to microbes in soil and leaf surfaces that can cause disease and result in crop losses and pathogen spread. Even though chemical treatment and genetic engineering have been successfully applied to combat disease, it is increasingly being recognized that understanding the natural co-evolution of plants with pathogens will provide new leads for pest regulation and, potentially, anticipate evolving pathogen strategies to evade recognition and cause disease. This new perspective requires understanding fundamental questions in the co-evolution between plants and pathogens using a combined genetic and molecular approach, and studying natural populations of plants that may be locally adapted. During the co-evolution with pathogens, plants have evolved mechanisms to distinguish foe from a benign or potentially beneficial microorganism and to induce appropriate defence reactions and anti-microbial molecules. However, activation of pathogen defence is likely costly for the plant as evidenced in growth defects exhibited by plants with constitutive activation of immune responses. As consequence, a proper balance between growth, reproduction and immune response had to be achieved during evolution, leading to an inducible immune system influenced by environmental fluctuations. The recent discovery of temperature-dependent hybrid incompatibilities in Arabidopsis thaliana allows at identifying genetic components at the intersection between plant immunity and the environment. Studying the molecular and genetic basis for such incompatibilities should provide novel insights into mechanisms underlying temperature regulation of plant immunity and local adaptation shaping genetic variation of immune-related genes.

Funding support


  • National Programme for Recruitment and Incorporation of Human Resources. Ramón y Cajal (RYC). Ministerio de Economía y Competitividad. Spain.
  • Marie Curie Actions. Career Integration Grants. FP7-PEOPLE-2011-CIG. EU.

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