Alex A. Cardenas Week 5: Difference between revisions

From OpenWetWare
Jump to navigationJump to search
No edit summary
No edit summary
Line 7: Line 7:
==Methods==
==Methods==
*15 injection drug users were observed in ALIVE study. Blood was taken and sampled every 6 months.  
*15 injection drug users were observed in ALIVE study. Blood was taken and sampled every 6 months.  
**After seroconversion, theses patients were followed and their CD4 T cell count is seen in this [http://www.pnas.org/content/95/21/12568/F1.large.jpg graph]
**After seroconversion, theses patients were followed and their CD4 T cell count is seen in this [http://www.pnas.org/content/95/21/12568/F1.large.jpg graph].
*Subjects were placed into 3 groups:
**Have AIDS: 1, 3, 4, 20, 22, 25
**Leaning toward AIDS: 7, 8, 9, 14
***These are 4 of the  6 moderate progressors that are leaning toward AIDS.
**Subjects who don't have AIDS: 2, 5, 6, 12, 13

Revision as of 14:40, 28 September 2011

Continued Research Project

  • 3 main points
    • Why did 6 of the 15 subjects develop AIDS and who has them? What did they have in common and what did they not have in common with subjects who did not develop AIDS?
    • The dS/dN ratios are used in hoping to prove whether or not the subject will develop AIDS depending on the low and high ratios.
    • Determine which subjects have AIDS and distinguish common factors for why each may have developed AIDS. From there we will compare them to subjects who do not have AIDS and see if they are on their way to develop AIDS.

Methods

  • 15 injection drug users were observed in ALIVE study. Blood was taken and sampled every 6 months.
    • After seroconversion, theses patients were followed and their CD4 T cell count is seen in this graph.
  • Subjects were placed into 3 groups:
    • Have AIDS: 1, 3, 4, 20, 22, 25
    • Leaning toward AIDS: 7, 8, 9, 14
      • These are 4 of the 6 moderate progressors that are leaning toward AIDS.
    • Subjects who don't have AIDS: 2, 5, 6, 12, 13