Alex A. Cardenas Week 9: Difference between revisions

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==HIV Structure Project Exercises==
==HIV Structure Project Exercises==
#Converting DNA sequences into protein sequences.
#Converting DNA sequences into protein sequences.
**The following sequences can be found [[media:SubjectSequences.doc here]]
**The following sequences can be found [[media:SubjectSequences.txt here]]
**This will be done by using STARbiochem.  
**This will be done by using STARbiochem.  
*
*

Revision as of 13:47, 26 October 2011

HIV Structure Project

  • Working with Robert and Zeb.
  • V3 loop conformation is the main area of study and comparing these regions with those who developed AIDs and those who did not. We will investigate these different conformations and how they compare with the given numbers such as CD4 T cell count, ratios, etc.
  • Rapid progressors sequences will be compared to moderate and non progressors. Subjects of interest are 1, 3, 4, 10, 11, and 15. Moderate progessors of interest 6 and non-progressor 13.
  • The following visits for each subject will be studied. We will be comparing pre and post AIDs (in relation to the # of CD4 T cell count). The conformational changes of the V3 loop will be looked at when the subjects have the highest CD4 T cell count and the lowest CD4 T cell count (except for the subjects 6 and 13).
    • Subject 1 - visit 1 and 3.
    • Subject 3 - visit 1 and 5.
    • Subject 4 - visit 1 and 4.
    • Subject 10 - visit 1 and 5.
    • Subject 11 - visit 1 and 4.
    • Subject 15 - visit 1 and 4.
    • Subject 6 (moderate progressor) - visit 1 and 9.
    • Subject 13 - visit 1 and 5.

HIV Structure Project Exercises

  1. Converting DNA sequences into protein sequences.

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