Alexander Kanitz: Difference between revisions

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==Previous labs==
==Previous labs==
*2004 - Institute of Biological Chemistry, Technical University of Munich, Germany: Production and characterization of the enzymatically active domain of the endolysine Ply500 isolated from Listeria monocytogenes-bacteriophage A 500
  *2004 - Institute of Biological Chemistry, Technical University of Munich, Germany: Production and characterization of the enzymatically active domain of the endolysine Ply500 isolated from Listeria monocytogenes-bacteriophage A 500


Supervisors: Dr. Ingo P. Korndörfer, Prof. Arne Skerra
Supervisors: Dr. Ingo P. Korndörfer, Prof. Arne Skerra

Revision as of 07:10, 13 August 2008

Contact Info

  • Alexander Kanitz
  • ETH Zurich
  • Department of Chemistry and Applied Biosciences
  • Institute of Pharmaceutical Sciences
  • Wolfgang Pauli-Strasse 10
  • 8093 Zurich
  • Switzerland
  • Contact me

I work in the Gerber Lab at the ETH Zurich.

Previous labs

 *2004 - Institute of Biological Chemistry, Technical University of Munich, Germany: Production and characterization of the enzymatically active domain of the endolysine Ply500 isolated from Listeria monocytogenes-bacteriophage A 500

Supervisors: Dr. Ingo P. Korndörfer, Prof. Arne Skerra

  • 2004-2005 - AMC Liver Center, University of Amsterdam, The Netherlands: Lentiviral Gene Transfer of Chemically Inducible Hepatocyte Growth Factor Receptor and Liver Re-Targeting of Lentiviral Particles

Supervisors: Dr. Jurgen Seppen, Prof. Ronald P.J. Oude-Elferink

  • 2006 - Institute of Molecular and Cell Biology, Biopolis, Singapore: "Characterization of a Putative IKK2 in Danio rerio"

Supervisor: Prof. Vinay Tergaonkar

Education

  • 2007-present, PhD student, ETH Zurich / Molecular Life Sciences Graduate School
  • 2004-2007, MSc Medical Biochemistry, University of Amsterdam
  • 2001-2004, BSc Molecular Biotechnology, Technical University of Munich

Research interests

I am interested in post-transcriptional regulatory networks, particularly the regulation of mRNA translation, localization and stability by RNA-binding proteins and non-coding RNAs ("mRNP code"). In our lab we are trying to decipher sequence or structural RNA regulatory elements with a primary focus on the human and yeast 3'UTRomes.

Publications

  1. Markusic DM, Kanitz A, Oude-Elferink RP, and Seppen J. Preferential gene transfer of lentiviral vectors to liver-derived cells, using a hepatitis B peptide displayed on GP64. Hum Gene Ther. 2007 Jul;18(7):673-9. DOI:10.1089/hum.2007.027 | PubMed ID:17630838 | HubMed [Paper1]
  2. Korndörfer IP, Kanitz A, Danzer J, Zimmer M, Loessner MJ, and Skerra A. Structural analysis of the L-alanoyl-D-glutamate endopeptidase domain of Listeria bacteriophage endolysin Ply500 reveals a new member of the LAS peptidase family. Acta Crystallogr D Biol Crystallogr. 2008 Jun;64(Pt 6):644-50. DOI:10.1107/S0907444908007890 | PubMed ID:18560152 | HubMed [Paper2]

All Medline abstracts: PubMed | HubMed

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