Alexander Kanitz

Home         What We Do         Publications         Resources         People         Photos         Links         Contact

Contact Info Alexander Kanitz ETH Zurich      Department of Chemistry and Applied Biosciences      Institute of Pharmaceutical Sciences / Pharmacogenomics Unit      Wolfgang Pauli-Strasse 10      8093 Zurich      Switzerland      Google Maps link Contact me here or write to alexander.kanitz@pharma.ethz.ch Research interests I am interested in post-transcriptional regulatory networks, particularly the regulation of mRNA translation, localization and stability by RNA-binding proteins and non-coding RNAs ("mRNP code"). In our lab we are trying to decipher sequence or structural RNA regulatory elements with a primary focus on the human and yeast 3'UTRomes. Current position I am a grad student in the Gerber Lab at the ETH Zurich, working on post-transcriptional gene regulation. Tentative title of the project: "Systematic Analysis of the Crosstalk between Regulatory RNA-Binding Proteins and the MicroRNA Machinery". I was recruited through the Molecular Life Sciences program of the Life Science Zurich Graduate School. Furthermore, I am a founding member of the miR Network Zurich (MiNZ). Previous labs 2006 - Tergaonkar Lab, Institute of Molecular and Cell Biology, Biopolis, Singapore: "Characterization of a Putative IKK2 in Danio rerio" / Supervisor: Prof. Vinay Tergaonkar 2004-2005 - Seppen Lab, AMC Liver Center, University of Amsterdam, The Netherlands: "Lentiviral Gene Transfer of Chemically Inducible Hepatocyte Growth Factor Receptor and Liver Re-Targeting of Lentiviral Particles" / Supervisors: Dr. Jurgen Seppen, Prof. Ronald P.J. Oude-Elferink 2004 - Skerra Lab, Institute of Biological Chemistry, Technical University of Munich, Germany: "Production and characterization of the enzymatically active domain of the endolysine Ply500 isolated from Listeria monocytogenes-bacteriophage A 500" / Supervisors: Dr. Ingo P. Korndörfer, Prof. Arne Skerra Education since 2007: PhD student, Life Science Zurich Graduate School, ETH Zurich 2004-2007: MSc Medical Biochemistry, University of Amsterdam 2001-2004: BSc Molecular Biotechnology, Technical University of Munich Publications Galgano A, Forrer M, Jaskiewicz L, Kanitz A, Zavolan M, and Gerber AP. Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system. PLoS One. 2008 Sep 8;3(9):e3164. DOI:10.1371/journal.pone.0003164 | Korndörfer IP, Kanitz A, Danzer J, Zimmer M, Loessner MJ, and Skerra A. Structural analysis of the L-alanoyl-D-glutamate endopeptidase domain of Listeria bacteriophage endolysin Ply500 reveals a new member of the LAS peptidase family. Acta Crystallogr D Biol Crystallogr. 2008 Jun;64(Pt 6):644-50. DOI:10.1107/S0907444908007890 | Markusic DM, Kanitz A, Oude-Elferink RP, and Seppen J. Preferential gene transfer of lentiviral vectors to liver-derived cells, using a hepatitis B peptide displayed on GP64. Hum Gene Ther. 2007 Jul;18(7):673-9. DOI:10.1089/hum.2007.027 | Useful links Gerber Lab on OWW Gerber Lab @ Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland Life Science Zurich Graduate School Tergaonkar Lab @ Institute of Molecular and Cell Biology, Biopolis, Singapore Seppen Lab @ AMC Liver Center, University of Amsterdam, The Netherlands Skerra Lab @ Institute of Biological Chemistry, Technical University of Munich, Germany (German only) <a href="http://www4.clustrmaps.com/counter/maps.php?url=http://openwetware.org/wiki/Alexander_Kanitz" id="clustrMapsLink"><img src="http://www4.clustrmaps.com/counter/index2.php?url=http://openwetware.org/wiki/Alexander_Kanitz" style="border:0px;" alt="Locations of visitors to this page" title="Locations of visitors to this page" id="clustrMapsImg" onerror="this.onerror=null; this.src='http://www2.clustrmaps.com/images/clustrmaps-back-soon.jpg'; document.getElementById('clustrMapsLink').href='http://www2.clustrmaps.com';" /> </a>