Alexander Kanitz: Difference between revisions
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==Contact | ==Contact information== | ||
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*ETH Zurich<br/> | *ETH Zurich<br/> | ||
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*Email: [mailto:alexander.kanitz@pharma.ethz.ch alexander.kanitz@pharma.ethz.ch] | *Email: [mailto:alexander.kanitz@pharma.ethz.ch alexander.kanitz@pharma.ethz.ch] | ||
==Research interests== | |||
*Gene regulatory networks | |||
*Laboratory automation / informatics ("Science 2.0") | |||
*Synthetic biology | |||
== | ==Current position== | ||
''' | '''11-2012 – present'''<br/> | ||
''' | '''RNA Regulatory Networks group, Institute of Molecular and Life Sciences, University of Zurich, Switzerland'''<br/> | ||
Post-doctoral fellow<br/> | |||
Supervision: Mihaela Zavolan | |||
==Research experience== | |||
== | '''09-2012 – 11-2012'''<br/> | ||
'''Statistical Genomics group, Institute of Molecular and Life Sciences, University of Zurich, Switzerland'''<br/> | |||
Supervision: Mark Robinson<br/> | |||
Project title: "Development of tools and methods for the analysis of ribosomal profiling data in the yeast Saccharomyces cerevisiae."<br/><br/> | |||
'''11-2007 – 06-2012'''<br/> | |||
'''11-2007 – | |||
'''Pharmacogenomics Unit, Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland'''<br/> | '''Pharmacogenomics Unit, Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland'''<br/> | ||
Supervision: | Supervision: André Gerber, Michael Detmar<br/> | ||
Project title: “Tools and strategies for the unraveling of post-transcriptional gene regulatory networks”<br/><br/> | Project title: “Tools and strategies for the unraveling of post-transcriptional gene regulatory networks”<br/><br/> | ||
'''12-2006 – 02-2007'''<br/> | '''12-2006 – 02-2007'''<br/> | ||
'''Swammerdam Institute of Life Sciences, University of Amsterdam, The Netherlands'''<br/> | '''Swammerdam Institute of Life Sciences, University of Amsterdam, The Netherlands'''<br/> | ||
Supervision: | Supervision: Stanley Brul, Hans van der Spek<br/> | ||
Project title: “Status, complications and future prospects of highly active antiretroviral therapy”<br/><br/> | Project title: “Status, complications and future prospects of highly active antiretroviral therapy”<br/><br/> | ||
'''02-2006 – 07-2006'''<br/> | '''02-2006 – 07-2006'''<br/> | ||
'''Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore'''<br/> | '''Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore'''<br/> | ||
Supervision: | Supervision: Vinay Tergaonkar<br/> | ||
Project title: “Characterization of a putative IKK2 in Danio Rerio”<br/><br/> | Project title: “Characterization of a putative IKK2 in Danio Rerio”<br/><br/> | ||
'''10-2004 – 09-2005'''<br/> | '''10-2004 – 09-2005'''<br/> | ||
'''Department of Hepatology, Academic Medical Center, University of Amsterdam, The Netherlands'''<br/> | '''Department of Hepatology, Academic Medical Center, University of Amsterdam, The Netherlands'''<br/> | ||
Supervision: | Supervision: Jurgen Seppen<br/> | ||
Project titles: ”Lentiviral gene transfer of chemically inducible hepatocyte growth factor receptor” and “Liver re-targeting of lentiviral particles”<br/><br/> | Project titles: ”Lentiviral gene transfer of chemically inducible hepatocyte growth factor receptor” and “Liver re-targeting of lentiviral particles”<br/><br/> | ||
'''03-2004 – 07-2004'''<br/> | '''03-2004 – 07-2004'''<br/> | ||
'''Institute of Biological Chemistry, Technical University of Munich, Germany'''<br/> | '''Institute of Biological Chemistry, Technical University of Munich, Germany'''<br/> | ||
Supervision: | Supervision: Arne Skerra, Ingo Korndörfer<br/> | ||
Project title: ”Production and characterization of the enzymatically active domain of the endolysine Ply500 isolated from Listeria monocytogenes bacteriophage A 500”<br/><br/> | Project title: ”Production and characterization of the enzymatically active domain of the endolysine Ply500 isolated from Listeria monocytogenes bacteriophage A 500”<br/><br/> | ||
'''08-2003 – 10-2003 & 07-2004 – 08-2004'''<br/> | '''08-2003 – 10-2003 & 07-2004 – 08-2004'''<br/> | ||
'''Traineeships Research and Development at Micromet, Inc., Munich, Germany''' | '''Traineeships Research and Development at Micromet, Inc., Munich, Germany''' | ||
==Acquired | ==Acquired skills== | ||
Experienced with transcriptomics (microarray) and proteomics (mass spectrometry) techniques as well as standard biochemical, molecular and cell biological techniques (cell culturing, cloning, Western/Northern blotting, immunopurification, qPCR, FACS, immunofluorescence, in vitro enzymatic and binding assays); used model systems: human cell lines, zebrafish, E. coli, P. pastoris, lentiviral vectors; profound knowledge of statistical and bioinformatics-based analytical methods (Perl, shell scripting & R/Bioconductor); highly developed scientific writing, data preparation, presentation and publication skills | |||
==Education== | |||
'''Molecular Life Sciences''', Ph.D., ETH Zurich, Switzerland (December 2011)<br/> | |||
'''Medical Biochemistry''', M.Sc., University of Amsterdam, The Netherlands (March 2007)<br/> | |||
'''Molecular Biotechnology''', B.Sc., Technical University of Munich, Germany (July 2004) | |||
==Expertise== | |||
Profound knowledge of gene regulatory systems and networks with a particular focus on post-transcriptional gene regulation; strong background in biochemistry, molecular biology, cell biology; familiarity with bioinformatics and biotechnology concepts and methods | |||
==Publications== | |||
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*<u>Kanitz A</u>. (2013). '''Post-Transcriptional Gene Regulation: Tools and Strategies for the Unraveling of Post-Transcriptional Gene Regulatory Networks'''. Based on dissertation #20147 at ETH Zurich. ''Südwestdeutscher Verlag für Hochschulschriften. ISBN-13: 978-3838136707'' | |||
*<u>Kanitz A</u>, Imig J, Dziunycz PJ, Primorac A, Galgano A, Hofbauer GFL, Gerber AP^, Detmar M^. (2012). '''The Expression Levels of MicroRNA-361-5p and Its Target VEGFA Are Inversely Correlated in Human Cutaneous Squamous Cell Carcinoma'''. ''PLoS One. 7(11):e49568'' | |||
*<u>Kanitz A</u>^, Imig J^, Gerber AP. (2012). '''RNA regulons and the RNA-protein interaction network'''. ''Biomol Concepts 3(5):403-414'' | |||
*<u>Kanitz A</u>, Gerber AP. (2010). '''Circuitry of mRNA regulation'''. ''Wiley Interdiscip Rev Syst Biol Med. 2(2):245-51'' | |||
* | |||
* | *Galgano A, Forrer M, Jaskiewicz L, <u>Kanitz A</u>, Zavolan M, Gerber AP. (2008). '''Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system'''. ''PLoS One. 3(9):e3164'' | ||
* | *Korndörder IP, <u>Kanitz A</u>, Danzer J, Zimmer M, Loessner MJ, Skerra A. (2008). '''Structural analysis of the L-alanoyl-D-glutamate endopeptidase domain of Listeria bacteriophage endolysin Ply500 reveals a member of the LAS peptidase family'''. ''Acta Crystallogr D Biol Crystallogr. 64(Pt 6):644-50'' | ||
*Markusic DM, <u>Kanitz A</u>, Oude-Elferink RP, Seppen J. (2007). '''Preferential gene transfer of lentiviral vectors to liver-derived cells, using a hepatitis B peptide displayed on GP64'''. ''Hum Gene Ther. 18(7):673-9'' | |||
< | |||
^ equal contribution | |||
==Links== | ==Links== | ||
*[http://gerber.openwetware.org Gerber Lab, ] | *[http://www.biozentrum.unibas.ch/research/groups-platforms/overview/unit/zavolan/ Zavolan Lab, Biozentrum, University of Basel, Switzerland] | ||
*[http://www.pharma.ethz.ch/institute_groups/pharmacogenomics/ Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland] | *[http://www.imls.uzh.ch/research/robinson.html Robinson Lab, Institute of Molecular and Life Sciences, University of Zurich, Switzerland] | ||
*[http://gerber.openwetware.org Gerber Lab, Institute of Biosciences and Medicine, University of Surrey, UK] | |||
*[http://www.pharma.ethz.ch/institute_groups/pharmacogenomics/ Detmar Lab, Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland] | |||
*[http://www.lifescience-graduateschool.ch/ Life Science Zurich Graduate School] | *[http://www.lifescience-graduateschool.ch/ Life Science Zurich Graduate School] | ||
*[http://www.imcb.a-star.edu.sg/php/vinayt.php Tergaonkar Lab, Institute of Molecular and Cell Biology, Singapore] | *[http://www.imcb.a-star.edu.sg/php/vinayt.php Tergaonkar Lab, Institute of Molecular and Cell Biology, Singapore] | ||
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Revision as of 05:38, 16 May 2013
Contact information
Department of Chemistry and Applied Biosciences Research interests
Current position11-2012 – present Research experience09-2012 – 11-2012 Acquired skillsExperienced with transcriptomics (microarray) and proteomics (mass spectrometry) techniques as well as standard biochemical, molecular and cell biological techniques (cell culturing, cloning, Western/Northern blotting, immunopurification, qPCR, FACS, immunofluorescence, in vitro enzymatic and binding assays); used model systems: human cell lines, zebrafish, E. coli, P. pastoris, lentiviral vectors; profound knowledge of statistical and bioinformatics-based analytical methods (Perl, shell scripting & R/Bioconductor); highly developed scientific writing, data preparation, presentation and publication skills EducationMolecular Life Sciences, Ph.D., ETH Zurich, Switzerland (December 2011) ExpertiseProfound knowledge of gene regulatory systems and networks with a particular focus on post-transcriptional gene regulation; strong background in biochemistry, molecular biology, cell biology; familiarity with bioinformatics and biotechnology concepts and methods Publications
^ equal contribution Links
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