Alexander Kanitz

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==Contact information==
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[[Image:Alex.JPG|120px|right]]
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*ETH Zurich<br/>
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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Department of Chemistry and Applied Biosciences<br/>
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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Institute of Pharmaceutical Sciences / Pharmacogenomics Unit<br/>
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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Wolfgang Pauli-Strasse 10<br/>
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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;8093 Zurich<br/>
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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Switzerland<br/>
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&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[http://maps.google.com/maps/ms?hl=en&ie=UTF8&cd=1&geocode=0,47.407532,8.507197&t=h&msa=0&ll=47.40625,8.510113&spn=0.020099,0.055361&z=15&msid=113355392983449396379.0004620333c5385a6a663 Google Maps link]<br/>
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*Email: [mailto:alexander.kanitz@pharma.ethz.ch alexander.kanitz@pharma.ethz.ch]
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==Research interests==
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*Gene regulatory networks
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*Laboratory automation / informatics ("Science 2.0")
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*Synthetic biology
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==Current position==
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'''I am currently looking for a post-doc position''' that allows me to apply and further develop my bioinformatics skills, ideally for the description of gene regulatory networks or the development of lab automation software/services.
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==Research experience==
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'''11-2007 – 12-2011'''<br/>
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'''Pharmacogenomics Unit, Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland'''<br/>
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Supervision: Prof. Dr. André Gerber, Prof. Dr. Michael Detmar<br/>
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Project title: “Tools and strategies for the unraveling of post-transcriptional gene regulatory networks”<br/><br/>
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'''12-2006 – 02-2007'''<br/>
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'''Swammerdam Institute of Life Sciences, University of Amsterdam, The Netherlands'''<br/>
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Supervision: Prof. Dr. Stanley Brul, Dr. Hans van der Spek<br/>
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Project title: “Status, complications and future prospects of highly active antiretroviral therapy”<br/><br/>
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'''02-2006 – 07-2006'''<br/>
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'''Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore'''<br/>
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Supervision: Prof. Dr. Vinay Tergaonkar<br/>
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Project title: “Characterization of a putative IKK2 in Danio Rerio”<br/><br/>
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'''10-2004 – 09-2005'''<br/>
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'''Department of Hepatology, Academic Medical Center, University of Amsterdam, The Netherlands'''<br/>
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Supervision: Prof. Dr. Jurgen Seppen<br/>
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Project titles: ”Lentiviral gene transfer of chemically inducible hepatocyte growth factor receptor” and “Liver re-targeting of lentiviral particles”<br/><br/>
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'''03-2004 – 07-2004'''<br/>
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'''Institute of Biological Chemistry, Technical University of Munich, Germany'''<br/>
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Supervision: Prof. Dr. Arne Skerra, Dr. habil. Ingo Korndörfer<br/>
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Project title: ”Production and characterization of the enzymatically active domain of the endolysine Ply500 isolated from Listeria monocytogenes bacteriophage A 500”<br/><br/>
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'''08-2003 – 10-2003 & 07-2004 – 08-2004'''<br/>
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'''Traineeships Research and Development at Micromet, Inc., Munich, Germany'''
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==Acquired skills==
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Experienced with transcriptomics (microarray) and proteomics (mass spectrometry) techniques as well as standard biochemical, molecular and cell biological techniques (cell culturing, cloning, Western/Northern blotting, immunopurification, qPCR, FACS, immunofluorescence, in vitro enzymatic and binding assays); used model systems: human cell lines, zebrafish, E. coli, P. pastoris, lentiviral vectors; profound knowledge of statistical and bioinformatics-based analytical methods (intermediate to advanced knowledge of Perl); highly developed scientific writing, data preparation, presentation and publication skills
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==Education==
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'''Molecular Life Sciences''', Ph.D., ETH Zurich, Switzerland (December 2011)<br/>
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'''Medical Biochemistry''', M.Sc., University of Amsterdam, The Netherlands (March 2007)<br/>
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'''Molecular Biotechnology''', B.Sc., Technical University of Munich, Germany (July 2004)
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==Expertise==
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Profound knowledge of gene regulatory systems and networks with a particular focus on post-transcriptional gene regulation; strong background in biochemistry, molecular biology, cell biology; familiarity with bioinformatics and biotechnology concepts and methods
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==Publications==
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<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications.  You can add or remove lines as needed -->
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*<u>Kanitz A</u>, Gerber AP. (2010). '''Circuitry of mRNA regulation'''. ''Wiley Interdiscip Rev Syst Biol Med. 2(2):245-51''
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*Galgano A, Forrer M, Jaskiewicz L, <u>Kanitz A</u>, Zavolan M, Gerber AP. (2008). '''Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system'''. ''PLoS One. 3(9):e3164''
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*Korndörder IP, <u>Kanitz A</u>, Danzer J, Zimmer M, Loessner MJ, Skerra A. (2008). '''Structural analysis of the L-alanoyl-D-glutamate endopeptidase domain of Listeria bacteriophage endolysin Ply500 reveals a member of the LAS peptidase family'''. ''Acta Crystallogr D Biol Crystallogr. 64(Pt 6):644-50''
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*Markusic DM, <u>Kanitz A</u>, Oude-Elferink RP, Seppen J. (2007). '''Preferential gene transfer of lentiviral vectors to liver-derived cells, using a hepatitis B peptide displayed on GP64'''. ''Hum Gene Ther. 18(7):673-9''
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==Links==
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*[http://gerber.openwetware.org Gerber Lab, Institute of Biosciences and Medicine, University of Surrey, UK]
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*[http://www.pharma.ethz.ch/institute_groups/pharmacogenomics/ Detmar Lab, Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland]
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*[http://www.lifescience-graduateschool.ch/ Life Science Zurich Graduate School]
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*[http://www.imcb.a-star.edu.sg/php/vinayt.php Tergaonkar Lab, Institute of Molecular and Cell Biology, Singapore]
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*[http://www.lrz-muenchen.de/~Biologische-Chemie/ Skerra Lab, Institute of Biological Chemistry, Technical University of Munich, Germany (German only)]
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