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| | #REDIRECT [[Talk:LiuGroup of CTGU]] |
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| ==Contact information==
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| [[Image:Alex.JPG|120px|right]]
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| *ETH Zurich<br/>
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| Department of Chemistry and Applied Biosciences<br/>
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| Institute of Pharmaceutical Sciences / Pharmacogenomics Unit<br/>
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| Wolfgang Pauli-Strasse 10<br/>
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| 8093 Zurich<br/>
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| Switzerland<br/>
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| [http://maps.google.com/maps/ms?hl=en&ie=UTF8&cd=1&geocode=0,47.407532,8.507197&t=h&msa=0&ll=47.40625,8.510113&spn=0.020099,0.055361&z=15&msid=113355392983449396379.0004620333c5385a6a663 Google Maps link]<br/>
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| *Email: [mailto:alexander.kanitz@pharma.ethz.ch alexander.kanitz@pharma.ethz.ch]
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| ==Research interests==
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| *Gene regulatory networks
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| *Laboratory automation / informatics ("Science 2.0")
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| *Synthetic biology
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| ==Current position==
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| '''I am currently looking for a post-doc position''' that allows me to apply and further develop my bioinformatics skills, ideally for the description of gene regulatory networks or the development of lab automation software/services.
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| ==Research experience==
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| '''09-2012 – 11-2012'''<br/>
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| '''Statistical Genomics group, Institute of Molecular and Life Sciences, University of Zurich, Switzerland'''<br/>
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| Supervision: Mark Robinson<br/>
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| Project Title: "Development of tools and methods for the analysis of ribosomal profiling data in the yeast Saccharomyces cerevisiae."<br/><br/>
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| '''11-2007 – 06-2012'''<br/>
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| '''Pharmacogenomics Unit, Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland'''<br/>
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| Supervision: André Gerber, Michael Detmar<br/>
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| Project title: “Tools and strategies for the unraveling of post-transcriptional gene regulatory networks”<br/><br/>
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| '''12-2006 – 02-2007'''<br/>
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| '''Swammerdam Institute of Life Sciences, University of Amsterdam, The Netherlands'''<br/>
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| Supervision: Stanley Brul, Hans van der Spek<br/>
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| Project title: “Status, complications and future prospects of highly active antiretroviral therapy”<br/><br/>
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| '''02-2006 – 07-2006'''<br/>
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| '''Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore'''<br/>
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| Supervision: Vinay Tergaonkar<br/>
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| Project title: “Characterization of a putative IKK2 in Danio Rerio”<br/><br/>
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| '''10-2004 – 09-2005'''<br/>
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| '''Department of Hepatology, Academic Medical Center, University of Amsterdam, The Netherlands'''<br/>
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| Supervision: Jurgen Seppen<br/>
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| Project titles: ”Lentiviral gene transfer of chemically inducible hepatocyte growth factor receptor” and “Liver re-targeting of lentiviral particles”<br/><br/>
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| '''03-2004 – 07-2004'''<br/>
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| '''Institute of Biological Chemistry, Technical University of Munich, Germany'''<br/>
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| Supervision: Arne Skerra, Ingo Korndörfer<br/>
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| Project title: ”Production and characterization of the enzymatically active domain of the endolysine Ply500 isolated from Listeria monocytogenes bacteriophage A 500”<br/><br/>
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| '''08-2003 – 10-2003 & 07-2004 – 08-2004'''<br/>
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| '''Traineeships Research and Development at Micromet, Inc., Munich, Germany'''
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| ==Acquired skills==
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| Experienced with transcriptomics (microarray) and proteomics (mass spectrometry) techniques as well as standard biochemical, molecular and cell biological techniques (cell culturing, cloning, Western/Northern blotting, immunopurification, qPCR, FACS, immunofluorescence, in vitro enzymatic and binding assays); used model systems: human cell lines, zebrafish, E. coli, P. pastoris, lentiviral vectors; profound knowledge of statistical and bioinformatics-based analytical methods (intermediate to advanced knowledge of Perl); highly developed scientific writing, data preparation, presentation and publication skills
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| ==Education==
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| '''Molecular Life Sciences''', Ph.D., ETH Zurich, Switzerland (December 2011)<br/>
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| '''Medical Biochemistry''', M.Sc., University of Amsterdam, The Netherlands (March 2007)<br/>
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| '''Molecular Biotechnology''', B.Sc., Technical University of Munich, Germany (July 2004)
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| ==Expertise==
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| Profound knowledge of gene regulatory systems and networks with a particular focus on post-transcriptional gene regulation; strong background in biochemistry, molecular biology, cell biology; familiarity with bioinformatics and biotechnology concepts and methods
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| ==Publications==
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| <!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications. You can add or remove lines as needed -->
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| *<u>Kanitz A</u>. (2013). '''Post-Transcriptional Gene Regulation: Tools and Strategies for the Unraveling of Post-Transcriptional Gene Regulatory Networks'''. Based on dissertation #20147 at ETH Zurich. ''Südwestdeutscher Verlag für Hochschulschriften. ISBN-13: 978-3838136707''
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| *<u>Kanitz A</u>, Imig J, Dziunycz PJ, Primorac A, Galgano A, Hofbauer GFL, Gerber AP^, Detmar M^. (2012). '''The Expression Levels of MicroRNA-361-5p and Its Target VEGFA Are Inversely Correlated in Human Cutaneous Squamous Cell Carcinoma'''. ''PLoS One. 7(11):e49568''
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| *<u>Kanitz A</u>^, Imig J^, Gerber AP. (2012). '''RNA regulons and the RNA-protein interaction network'''. ''Biomol Concepts 3(5):403-414''
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| *<u>Kanitz A</u>, Gerber AP. (2010). '''Circuitry of mRNA regulation'''. ''Wiley Interdiscip Rev Syst Biol Med. 2(2):245-51''
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| *Galgano A, Forrer M, Jaskiewicz L, <u>Kanitz A</u>, Zavolan M, Gerber AP. (2008). '''Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system'''. ''PLoS One. 3(9):e3164''
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| *Korndörder IP, <u>Kanitz A</u>, Danzer J, Zimmer M, Loessner MJ, Skerra A. (2008). '''Structural analysis of the L-alanoyl-D-glutamate endopeptidase domain of Listeria bacteriophage endolysin Ply500 reveals a member of the LAS peptidase family'''. ''Acta Crystallogr D Biol Crystallogr. 64(Pt 6):644-50''
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| *Markusic DM, <u>Kanitz A</u>, Oude-Elferink RP, Seppen J. (2007). '''Preferential gene transfer of lentiviral vectors to liver-derived cells, using a hepatitis B peptide displayed on GP64'''. ''Hum Gene Ther. 18(7):673-9''
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| ^ equal contribution
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| ==Links==
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| *[http://gerber.openwetware.org Gerber Lab, Institute of Biosciences and Medicine, University of Surrey, UK]
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| *[http://www.pharma.ethz.ch/institute_groups/pharmacogenomics/ Detmar Lab, Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland]
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| *[http://www.lifescience-graduateschool.ch/ Life Science Zurich Graduate School]
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| *[http://www.imcb.a-star.edu.sg/php/vinayt.php Tergaonkar Lab, Institute of Molecular and Cell Biology, Singapore]
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| *[http://www.lrz-muenchen.de/~Biologische-Chemie/ Skerra Lab, Institute of Biological Chemistry, Technical University of Munich, Germany (German only)]
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| <a href="http://www4.clustrmaps.com/user/c84798ac"><img src="http://www4.clustrmaps.com/stats/maps-no_clusters/openwetware.org-wiki-Alexander_Kanitz-thumb.jpg" alt="Locations of visitors to this page" />
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