Alik:Reprints

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'''PUBLICATIONS:'''
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{{Alik}}
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Journals Articles:
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__TOC__
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''In preparation''
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==Journals Articles:==
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1. B. Murtuza, R. Langer, A. Khademhosseini. “Micropatterning and microfluidics for cardiac tissue engineering” (In preparation).
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===In preparation===
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#B. Murtuza, R. Langer, A. Khademhosseini. “Micropatterning and microfluidics for cardiac tissue engineering” (In preparation).
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2. J. Yeh, A. Khademhosseini, J. Fukuda, J. Karp, G. Eng, R. Langer.  “Microstructure mediated patterned co-cultures” (In preparation).
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#J. Yeh, A. Khademhosseini, J. Fukuda, J. Karp, G. Eng, R. Langer.  “Microstructure mediated patterned co-cultures” (In preparation).
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3. A. Khademhosseini, J. Karp, J. Yeh, J. Fukuda, G. Eng, S. Lee, C. Verbeke, R. Langer, M. Dokmeci.  “Parylene membranes for cell and protein patterning” (In preparation).
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''2006''
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4. A. Khademhosseini*, L. Ferreira*, J. Yeh, J. Blumling, J. Fukuda, G. Eng, R. Langer.  “Co-cultures of human embryonic stem cells and murine embryonic feeder cells on microwell patterned surfaces” Biomaterials (Submitted).
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+
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5. Y. Ling*, J. Yeh*, J. Gantz, J. Yeh, G. Eng, J. Fukuda, R. Langer, A. Khademhosseini.  “Micromolding of photocrosslinkable hydrogels for cell encapsulation” Tissue Engineering (Submitted).
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+
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6. J. Karp*, J. Yeh*, G. Eng, J. Fukuda, J. Blumling, K.Y. Suh, J. Cheng, J. Borenstein, R. Langer, A. Khademhosseini.  “Controlling size, shape and homogeneity of embryoid bodies using polymeric microwells” Stem cells (Submitted).
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+
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7. K. Y. Suh, A. Khademhosseini, S.Y. Jon, R. Langer.  “Confinement of an individual M13 virus within a poly(ethylene glycol) nanowells” Nanoletters  (Submitted)
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8. A. Khademhosseini, J. Karp, C. Bettinger,  J. Yeh, Y. Ling, J. Borenstein, J. Fukuda, R. Langer.  “Biomaterials and microscale technologies: building on each other to advance biomedical applications”  Journal of Biomaterials Science:  Polymer Edition (Submitted)
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+
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9. P. Kim, H.E. Jeong, A. Khademhosseini, K.Y. Suh “Fabrication of non-biofouling polyethylene glycol (PEG) micro- to nanochannels by ultraviolet-assisted irreversible sealing”  Advanced Materials (Submitted). 
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10. J. Fukuda, A. Khademhosseini, Y. Yeo, J. Yeh, X. Yang, G. Eng, J. Blumling, C.F. Wang, D.S. Kohane, R. Langer.  “Micromolding of photocrosslinkable chitosan hydrogel for spheroid microarray and co-cultures” Biomaterials (Submitted).
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11. A. Khademhosseini, J. Yeh, G. Eng, S. Kucharczyk, R. Langer, G. Vunjak-Novakovic, M. Radisic  “Microfluidic patterning for fabrication of contractile cardiac organoids” Biomedical Microdevices (Submitted).
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12. A. Khademhosseini, G. Eng, J. Yeh, J. Fukuda, J. Blumling, R. Langer, J. Burdick.  “Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment” Journal of Biomedical Materials Research: Part B Applied Biomaterials In Press (2006).
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13. A. Khademhosseini, R. Langer.  “Nanobiotechnolgy for Tissue Engineering and Drug Delivery” Chemical Engineering Progress In press (2006).
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14. J. Cheng, B. Teply, C. Yim, S.Y. Jeong, I. Sherifi, S. Jon, A. Khademhosseini, O.C. Farokhzad, R. Langer. “Magnetite-PLGA-Insulin Microparticles: Novel Magnetically Responsive Vehicles for Oral Protein Delivery” Pharmaceutical Research In press (2006).
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15. N. Peppas, Z. Hilt, A. Khademhosseini, R. Langer. “Hydrogels in Biomedical applications:  From fundamentals to nanobiotechnology”.  Advanced Materials In press (2006).
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16. A. Khademhosseini, R. Langer, J. Borenstein, J. Vacanti.  “Microscale Technologies for Tissue Engineering and Biology” Proceedings of National Academy of Sciences USA  103:2480-2487 (2006).
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2005
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17. J.M. Karp, L.S. Ferreira, A. Khademhosseini, A.H. Kwon, J. Yeh, R. Langer “Cultivation of Human Embryonic Stem Cells without the Embryoid Body step enhances osteogenesis in vitro” Stem Cells In press (2005)
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18. A. Khademhosseini*, J. Fukuda*, J. Yeh, G. Eng, R. Langer.  “Layer-by-layer deposition of HA and collagen for patterned cell co-cultures” Biomaterials 27(8): 1479-1486 (2006).
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+
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19. A. Khademhosseini, M.H. May, M.V. Sefton.  “Conformal Coating of Mammalian Cells Immobilized onto Magnetically Driven Beads” Tissue Engineering 11(11) 1797-1806 (2005).
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20. A. Khademhosseini, J. Yeh, G. Eng, H. Kazi, J. Borenstein, J. Karp, O. Farokhzad, R. Langer.  “Cell docking inside microwells within reversibly sealed microfluidic channels for multiphenotype cellular arrays” Lab on a Chip 5(12):1380-6 (2005). (Cover feature – also featured as a news article in Analytical Chemistry 78(3): 642 (2006)).
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21. A. Khademhosseini.  “Chips to Hits: microarrays and microfluidic technologies for high-throughput analysis and drug discovery” Expert Reviews of Molecular Diagnostics 5(6):  843-846 (2005).
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22. P. Kim, D.–H. Kim, B. Kim, S. K. Choi, S. H. Lee, A. Khademhosseini, R. Langer, K. Y. Suh, “Fabrication of nanostructures of poly(ethylene glycol) for protein adsorption and cell adhesion” Nanotechnology 16: 2420-2426 (2005).
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23. A. Khademhosseini*, O.C. Farokhzad*, S.Y. Jon, A. Hermmann, J.J. Cheng, C. Chin, A. Kiselyuk, G. Eng, B. Teply, R. Langer,.  “Microfluidic System for Studying the Interaction of Nanoparticles and Microparticles with Cells” Analytical Chemistry  77(17): 5453-5459 (2005)
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24. K.Y. Suh, J.M. Yang, A. Khademhosseini, D. Berry, T.T. Tran, H. Park, and R. Langer “Characterization of Chemisorbed Hyaluronic Acid Directly Immobilized on Solid Substrates”, Journal of Biomedical Materials Research: Part B  Applied Biomaterials  72(B): 292-298 (2005).
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  2004
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25. O.C. Farokhzad, S.Y. Jon, A. Khademhosseini, T.T. Tran, D. LaVan, R. Langer.  “Nanoparticle-Aptamer Bioconjugates: A New Approach for Targeting Prostate Cancer Cells” Cancer Research 64(21):7668-7672 (2004).
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26. K.Y. Suh, K. Yoon, H.H. Lee, A. Khademhosseini, R. Langer.  “Solventless ordering of colloidal particles through the applicant of patterned elastomeric stamps under pressure”, Applied Physics Letters 85 (13): 2643-2645 (2004).
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27. K. Y. Suh, A. Khademhosseini, P.J. Yoo, R. Langer.  “Patterning and separating infected bacteria using host-parasite and virus-antibody interactions” Biomedical Microdevices 6 (3):223-229 (2004).
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28. S. Jaffar, K.T. Nam, A. Khademhosseini, J. Xing, R. Langer, A. Belcher. “Layer-by-layer surface modification and patterned electrostatic deposition of quantum dots” Nano Letters 4(8); 1421-1425 (2004).
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29. A. Khademhosseini, J. Yeh, S.Y. Jon, G. Eng, K.Y. Suh, J. Burdick, R. Langer.  “Molded poly(ethylene glycol) microstructures for docking and shear protecting cells within microfluidic channels” Lab on a chip 4; 425 - 430 (2004).
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+
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30. K.Y. Suh, A. Khademohsseini, G. Eng, R. Langer.  “Single nanocrystal arrays on patterned poly(ethylene glycol) copolymer microstructures using selective wetting and drying” Langmuir 20 (15): 6080-6084 (2004).
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+
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31. A. Khademhosseini, K.Y. Suh, S.Y. Jon, G. Chen, G. Eng, J. Yeh, R. Langer.  “A soft lithographic approach for fabricating patterned microfluidic channels” Analytical Chemistry 76 (13): 3675-3681 (2004).
+
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+
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32. A. Khademhosseini*, J. Burdick*, R. Langer.  “Fabrication of Gradient Hydrogels Using a Microfluidics/Photopolymerization Process”. Langmuir 20 (13): 5153-5156 (2004).
+
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+
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33. K.Y. Suh, A. Khademhosseini, J.M. Yang, T.T. Tran, G. Eng, and R. Langer “Soft lithographic patterning of hyaluronic acid on solid substrates using molding and printing”, Advanced Materials  16 (7): 584-588 (2004).
+
-
 
+
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34. A. Khademhosseini, K.Y. Suh, J.M. Yang, G. Eng, J. Yeh, S. Levenberg, R. Langer.  “Layer-by-layer deposition of hyaluronic acid and poly-L-lysine for patterned cell co-cultures”, Biomaterials, 25: 3583-3592 (2004).
+
-
 
+
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35. K.Y. Suh, J. Seong, A. Khademhosseini, P. E. Laibinis, R. Langer.  “Patterned deposition of proteins and cells using a molding technique”. Biomaterials, 25: 557-563 (2004).
+
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+
-
  2003
+
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36. A.  Khademhosseini, S. Jon,  K.Y. Suh, G. Eng, J. Yeh, T.T. Tran, R. Langer. “Direct patterning of cell and protein resistant polymeric monolayer and microstructures”.  Advanced Materials 15 (23): 1995-2000 (2003).
+
-
+
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37. S. Jon, J. Seong, A. Khademhosseini, T.T. Tran, P.E. Laibinis, R. Langer. “Construction of non-biofouling surfaces by polymeric self-assembled monolayers”.  Langmuir, 19 (15): 9989-9993 (2003).
+
 +
===2006===
 +
#A. Khademhosseini*, L. Ferreira*, J. Yeh, J. Blumling, J. Fukuda, G. Eng, R. Langer.  “Co-cultures of human embryonic stem cells and murine embryonic feeder cells on microwell patterned surfaces” Biomaterials (Submitted).
 +
#Y. Ling*, J. Yeh*, J. Gantz, J. Yeh, G. Eng, J. Fukuda, R. Langer, A. Khademhosseini.  “Micromolding of photocrosslinkable hydrogels for cell encapsulation” Tissue Engineering (Submitted).
 +
#J. Karp*, J. Yeh*, G. Eng, J. Fukuda, J. Blumling, K.Y. Suh, J. Cheng, J. Borenstein, R. Langer, A. Khademhosseini.  “Controlling size, shape and homogeneity of embryoid bodies using polymeric microwells” Stem cells (Submitted).
 +
#K. Y. Suh, A. Khademhosseini, S.Y. Jon, R. Langer.  “Confinement of an individual M13 virus within a poly(ethylene glycol) nanowells” Nanoletters  (Submitted)
 +
#A. Khademhosseini, J. Karp, C. Bettinger,  J. Yeh, Y. Ling, J. Borenstein, J. Fukuda, R. Langer.  “Biomaterials and microscale technologies: building on each other to advance biomedical applications”  Journal of Biomaterials Science:  Polymer Edition (Submitted)
 +
#P. Kim, H.E. Jeong, A. Khademhosseini, K.Y. Suh “Fabrication of non-biofouling polyethylene glycol (PEG) micro- to nanochannels by ultraviolet-assisted irreversible sealing”  Advanced Materials (Submitted). 
 +
#J. Fukuda, A. Khademhosseini, Y. Yeo, J. Yeh, X. Yang, G. Eng, J. Blumling, C.F. Wang, D.S. Kohane, R. Langer.  “Micromolding of photocrosslinkable chitosan hydrogel for spheroid microarray and co-cultures” Biomaterials (Submitted).
 +
#A. Khademhosseini, J. Yeh, G. Eng, S. Kucharczyk, R. Langer, G. Vunjak-Novakovic, M. Radisic  “Microfluidic patterning for fabrication of contractile cardiac organoids” Biomedical Microdevices (Submitted).
 +
#A. Khademhosseini, G. Eng, J. Yeh, J. Fukuda, J. Blumling, R. Langer, J. Burdick.  “Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment” Journal of Biomedical Materials Research: Part B Applied Biomaterials In Press (2006).
 +
#A. Khademhosseini, R. Langer.  “Nanobiotechnolgy for Tissue Engineering and Drug Delivery” Chemical Engineering Progress In press (2006).
 +
#J. Cheng, B. Teply, C. Yim, S.Y. Jeong, I. Sherifi, S. Jon, A. Khademhosseini, O.C. Farokhzad, R. Langer. “Magnetite-PLGA-Insulin Microparticles: Novel Magnetically Responsive Vehicles for Oral Protein Delivery” Pharmaceutical Research In press (2006).
 +
#N. Peppas, Z. Hilt, A. Khademhosseini, R. Langer. “Hydrogels in Biomedical applications:  From fundamentals to nanobiotechnology”.  Advanced Materials In press (2006).
 +
#A. Khademhosseini, R. Langer, J. Borenstein, J. Vacanti.  “Microscale Technologies for Tissue Engineering and Biology” Proceedings of National Academy of Sciences USA  103:2480-2487 (2006).
 +
===2005===
 +
#J.M. Karp, L.S. Ferreira, A. Khademhosseini, A.H. Kwon, J. Yeh, R. Langer “Cultivation of Human Embryonic Stem Cells without the Embryoid Body step enhances osteogenesis in vitro” Stem Cells In press (2005)
 +
#A. Khademhosseini*, J. Fukuda*, J. Yeh, G. Eng, R. Langer.  “Layer-by-layer deposition of HA and collagen for patterned cell co-cultures” Biomaterials 27(8): 1479-1486 (2006).
 +
#A. Khademhosseini, M.H. May, M.V. Sefton.  “Conformal Coating of Mammalian Cells Immobilized onto Magnetically Driven Beads” Tissue Engineering 11(11) 1797-1806 (2005).
 +
#A. Khademhosseini, J. Yeh, G. Eng, H. Kazi, J. Borenstein, J. Karp, O. Farokhzad, R. Langer.  “Cell docking inside microwells within reversibly sealed microfluidic channels for multiphenotype cellular arrays” Lab on a Chip 5(12):1380-6 (2005). (Cover feature – also featured as a news article in Analytical Chemistry 78(3): 642 (2006)).
 +
#A. Khademhosseini.  “Chips to Hits: microarrays and microfluidic technologies for high-throughput analysis and drug discovery” Expert Reviews of Molecular Diagnostics 5(6):  843-846 (2005).
 +
#P. Kim, D.–H. Kim, B. Kim, S. K. Choi, S. H. Lee, A. Khademhosseini, R. Langer, K. Y. Suh, “Fabrication of nanostructures of poly(ethylene glycol) for protein adsorption and cell adhesion” Nanotechnology 16: 2420-2426 (2005).
 +
#A. Khademhosseini*, O.C. Farokhzad*, S.Y. Jon, A. Hermmann, J.J. Cheng, C. Chin, A. Kiselyuk, G. Eng, B. Teply, R. Langer,.  “Microfluidic System for Studying the Interaction of Nanoparticles and Microparticles with Cells” Analytical Chemistry  77(17): 5453-5459 (2005)
 +
#K.Y. Suh, J.M. Yang, A. Khademhosseini, D. Berry, T.T. Tran, H. Park, and R. Langer “Characterization of Chemisorbed Hyaluronic Acid Directly Immobilized on Solid Substrates”, Journal of Biomedical Materials Research: Part B  Applied Biomaterials  72(B): 292-298 (2005).
 +
===2004===
 +
#O.C. Farokhzad, S.Y. Jon, A. Khademhosseini, T.T. Tran, D. LaVan, R. Langer.  “Nanoparticle-Aptamer Bioconjugates: A New Approach for Targeting Prostate Cancer Cells” Cancer Research 64(21):7668-7672 (2004).
 +
#K.Y. Suh, K. Yoon, H.H. Lee, A. Khademhosseini, R. Langer.  “Solventless ordering of colloidal particles through the applicant of patterned elastomeric stamps under pressure”, Applied Physics Letters 85 (13): 2643-2645 (2004).
 +
#K. Y. Suh, A. Khademhosseini, P.J. Yoo, R. Langer.  “Patterning and separating infected bacteria using host-parasite and virus-antibody interactions” Biomedical Microdevices 6 (3):223-229 (2004).
 +
#S. Jaffar, K.T. Nam, A. Khademhosseini, J. Xing, R. Langer, A. Belcher. “Layer-by-layer surface modification and patterned electrostatic deposition of quantum dots” Nano Letters 4(8); 1421-1425 (2004).
 +
#A. Khademhosseini, J. Yeh, S.Y. Jon, G. Eng, K.Y. Suh, J. Burdick, R. Langer.  “Molded poly(ethylene glycol) microstructures for docking and shear protecting cells within microfluidic channels” Lab on a chip 4; 425 - 430 (2004).
 +
#K.Y. Suh, A. Khademohsseini, G. Eng, R. Langer.  “Single nanocrystal arrays on patterned poly(ethylene glycol) copolymer microstructures using selective wetting and drying” Langmuir 20 (15): 6080-6084 (2004).
 +
#A. Khademhosseini, K.Y. Suh, S.Y. Jon, G. Chen, G. Eng, J. Yeh, R. Langer.  “A soft lithographic approach for fabricating patterned microfluidic channels” Analytical Chemistry 76 (13): 3675-3681 (2004).
 +
#A. Khademhosseini*, J. Burdick*, R. Langer.  “Fabrication of Gradient Hydrogels Using a Microfluidics/Photopolymerization Process”. Langmuir 20 (13): 5153-5156 (2004).
 +
#K.Y. Suh, A. Khademhosseini, J.M. Yang, T.T. Tran, G. Eng, and R. Langer “Soft lithographic patterning of hyaluronic acid on solid substrates using molding and printing”, Advanced Materials  16 (7): 584-588 (2004).
 +
#A. Khademhosseini, K.Y. Suh, J.M. Yang, G. Eng, J. Yeh, S. Levenberg, R. Langer.  “Layer-by-layer deposition of hyaluronic acid and poly-L-lysine for patterned cell co-cultures”, Biomaterials, 25: 3583-3592 (2004).
 +
#K.Y. Suh, J. Seong, A. Khademhosseini, P. E. Laibinis, R. Langer.  “Patterned deposition of proteins and cells using a molding technique”. Biomaterials, 25: 557-563 (2004).
 +
===2003===
 +
#A.  Khademhosseini, S. Jon,  K.Y. Suh, G. Eng, J. Yeh, T.T. Tran, R. Langer. “Direct patterning of cell and protein resistant polymeric monolayer and microstructures”.  Advanced Materials 15 (23): 1995-2000 (2003).
 +
#S. Jon, J. Seong, A. Khademhosseini, T.T. Tran, P.E. Laibinis, R. Langer. “Construction of non-biofouling surfaces by polymeric self-assembled monolayers”.  Langmuir, 19 (15): 9989-9993 (2003).
*denotes equal contribution by authors.
*denotes equal contribution by authors.
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Book Chapters:
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==Book Chapters:==
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38. J. Karp, L. Ferreira, A. Khademhosseini, R. Langer.  “in vitro differentiation of Human ES cells down osteogenic pathways” in  “Embryonic Stem Cells: a practical handbook”,  Editors, Stephen Sullivan, Kevin Eggan and Chad Cowan,  John Wiley & Sons  (2006) (In preparation)
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#J. Karp, L. Ferreira, A. Khademhosseini, R. Langer.  “in vitro differentiation of Human ES cells down osteogenic pathways” in  “Embryonic Stem Cells: a practical handbook”,  Editors, Stephen Sullivan, Kevin Eggan and Chad Cowan,  John Wiley & Sons  (2006) (In preparation)
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#A. Khademhosseini, Y. Ling, J. Karp, R. Langer.  “Nanofabricated structures for tissue engineering”.  Nanobiotechnology:  Concepts, Applications and Perspectives”,  Editors, Chad A. Mirkin and Christof M. Neimeyer,  Wiley-VCH (2006).
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39. A. Khademhosseini, Y. Ling, J. Karp, R. Langer.  “Nanofabricated structures for tissue engineering”.  Nanobiotechnology:  Concepts, Applications and Perspectives”,  Editors, Chad A. Mirkin and Christof M. Neimeyer,  Wiley-VCH (2006).
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#A. Khademhosseini, S. Gretchet-Nir, J. Karp, L. Ferreira, G. Vunjak-Novakovic, R. Langer.  “Embryonic stem cells in tissue engineering”.  Principles of Tissue Engineering, 3rd Edition, Editor: Robert Lanza, Academic Press (2006).
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#S. Levenberg, A. Khademhosseini, R. Langer.  “Embryonic stem cells and tissue engineering”.  In “Handbook of Stem Cells”, Editors: Editors Doug Melton, James Thomson, John Gearhart, Brigid Hogan, Ron McKay, Roger Pedersen, Mike West and Robert Lanza, Academic Press (2004).
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40. A. Khademhosseini, S. Gretchet-Nir, J. Karp, L. Ferreira, G. Vunjak-Novakovic, R. Langer.  “Embryonic stem cells in tissue engineering”.  Principles of Tissue Engineering, 3rd Edition, Editor: Robert Lanza, Academic Press (2006).
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#S. Levenberg, A. Khademhosseini, R. Langer.  “Embryonic stem cells and tissue engineering”.  In “Essentials of Stem Cell Biology”, Editors: Robert Lanza, John Gearhart, Brigid Hogan, Douglas Melton, Roger Pedersen, James Thomson, E. Donnall Thomas, Irving Weissman, Michael West, Academic Press (2004).
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#S. Levenberg, A. Khademhosseini, M. McDonald, J. Fuller, R. Langer.  “Methods of (human) embryonic stem cell culture”.  Chapter 3 in “Culture of cells for tissue engineering”, Editors I. Freshney and G. Vunjak-Novakovic, Humana Press (2004).  
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41. S. Levenberg, A. Khademhosseini, R. Langer.  “Embryonic stem cells and tissue engineering”.  In “Handbook of Stem Cells”, Editors: Editors Doug Melton, James Thomson, John Gearhart, Brigid Hogan, Ron McKay, Roger Pedersen, Mike West and Robert Lanza, Academic Press (2004).
+
#A. Khademhosseini, P.W. Zandstra.  “Engineering the in vitro cellular microenvironment for the control and manipulation of adult stem cell responses”.  In “Adult stem cells”, Editor K. Turksen, Ch. 15, p 289-314, Humana Press (2003).
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+
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42. S. Levenberg, A. Khademhosseini, R. Langer.  “Embryonic stem cells and tissue engineering”.  In “Essentials of Stem Cell Biology”, Editors: Robert Lanza, John Gearhart, Brigid Hogan, Douglas Melton, Roger Pedersen, James Thomson, E. Donnall Thomas, Irving Weissman, Michael West, Academic Press (2004).
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+
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43. S. Levenberg, A. Khademhosseini, M. McDonald, J. Fuller, R. Langer.  “Methods of (human) embryonic stem cell culture”.  Chapter 3 in “Culture of cells for tissue engineering”, Editors I. Freshney and G. Vunjak-Novakovic, Humana Press (2004).  
+
-
 
+
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44. A. Khademhosseini, P.W. Zandstra.  “Engineering the in vitro cellular microenvironment for the control and manipulation of adult stem cell responses”.  In “Adult stem cells”, Editor K. Turksen, Ch. 15, p 289-314, Humana Press (2003).
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Patents / Technology disclosures:
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1. A. Khademhosseini, J. Karp, D. Berry, R. Langer, “Tooth Whitening”, Submitted to the MIT Technology Licensing Office (March. 2006).
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2. A. Khademhosseini, J. Karp, L. Ferreira, Y. Yoon, R. Langer, “Highly efficient dessicants”, Submitted to the MIT Technology Licensing Office (March. 2006).
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3. A. Khademhosseini, J. Karp, O. Farokhzad, R. Langer, “Microencapsulation of cells within shape-controlled biomaterials as building blocks for engineering tissues and organs.”, Submitted to the MIT Technology Licensing Office (Jan. 2006).
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4. A. Khademhosseini, J. Karp, G. Eng, J. Yeh, R. Langer, “Template based tissue engineering”, Submitted to the MIT Technology Licensing Office (Sept. 2005).
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5. A. Khademhosseini, J. Karp, M. Moore, R. Langer, “A Platform Technology Based on Bioactive Hydrogels”, Submitted to the MIT Technology Licensing Office (Aug. 2005).
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6. A. Khademhosseini, J. Yeh, G. Eng, J. Borenstein, R. Langer.  “Multi-phenotype cellular arrays within microfluidic channels”, Submitted to the MIT Technology Licensing Office (Feb. 2005).
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7. A. Khademhosseini, O. Farokhzad, R. Langer, “High Throughput Synthesis of Functionalized Materials”, filed to USA Patent Office (Dec. 2005) -  Patent Pending.
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8. A. Khademhosseini, J. Karp, L.S. Ferreira, R. Langer “Improved differentiation of human embryonic stem cells to osteogenic cells” filed to USA Patent Office (Sept. 2005) -  Patent Pending.
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9. A. Khademhosseini, K.Y. Suh, S.Y. Jon, R. Langer.  “Patterned surfaces and polymeric microstructures within robust microfluidic channels” filed to USA Patent Office (Feb. 2005) - Patent Pending.
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10. A. Khademhosseini, K.Y. Suh, D. Berry, R. Sasisekharan, R. Langer.  “Deposition of glycosaminoglycans to form biologically active surfaces” filed to USA Patent Office (Sept. 2004) - Patent Pending.
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Conference Proceedings / Abstracts:
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  2006
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1. A. Khademhosseini. “Microscale technologies in tissue engineering”, Digital Fabrication Conference, Denver, CO (Sept. 2006). (Keynote speaker)
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+
-
2. A. Khademhosseini, L.S. Ferreira, J.M. Karp, J. Blumling III, J. Yeh, J. Fukuda, G. Eng, J. Gantz, and R. Langer. “Micropatterned Co-cultures of Human Embryonic Stem Cells with Murine Embryonic Fibroblasts”, 2006 International Society of Stem cell Research Meeting, Toronto, ON (June 2006).
+
-
 
+
-
3. J. Yeh, J. M. Karp, G. Eng, J. Fukuda, J. Blumling, R. Langer, A. Khademhosseini.  “Controlling size, shape, and homogeneity of embryonic stem cell aggregates and embryoid bodies within poly(ethylene glycol) microwells”, 2006 International Society of Stem cell Research Meeting, Toronto, ON (June 2006).
+
-
 
+
-
4. Y. Ling, J. Yeh, J. M. Karp, A. Chandawarkar, J. Gantz, R. Langer, A. Khademhosseini.  “Shape and size-controlled photocrosslinkable microgels for encapsulation of embryonic stem cells”, 2006 International Society of Stem cell Research Meeting, Toronto, ON (June 2006).
+
-
 
+
-
5. J.M. Karp, L.S. Ferreira; A. Khademhosseini, A. Kwan, J. Yeh, R. Langer. “Exclusion of the embryoid body step improves the differentiation efficiency of human embryonic stem cells into osteoblasts”, 2006 International Society of Stem cell Research Meeting, Toronto, ON (June 2006).
+
-
 
+
-
6. J.M. Karp, A. Khademhosseini, L.S. Ferreira, A. Kwan, J. Yeh, R. Langer. “Micropatterned Co-cultures of Human Embryonic Stem Cells with Murine Embryonic Fibroblasts”, Canadian Society for Biomaterials Annual Meeting, Calgary, AL (May 26th-28th 2006)
+
-
 
+
-
7. J.M. Karp, L.S. Ferreira, A. Khademhosseini, A.. Kwan, O. Farokhzad, J. Yeh, R. Langer. “Amplification of Osteogenic Cells from Human Embryonic Stem Cells”, Society for Biomaterials Meeting, Pittsburgh, PA (March, 2006).
+
-
 
+
-
8. J.M. Karp, L.S. Ferreira, A. Khademhosseini, R. Li, N. Choodnovskiy, K. Yan, R. Langer. “Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro”, 52nd Annual Orthopedic Research Society, Chicago, IL (March, 2006).
+
-
 
+
-
9. A. Khademhosseini, G. Eng, J. Yeh, J. Fukuda, J. Blumling III, J.M. Karp, R. Langer,  J.A. Burdick.  “Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment”, Society for Biomaterials Meeting, Pittsburgh, PA (March, 2006).
+
-
 
+
-
10. A. Khademhosseini.  “Academic position search:  Perspectives from a recent faculty candidate”, Society for Biomaterials Meeting, Pittsburgh, PA (March, 2006). (Invited speaker)
+
-
 
+
-
11. A. Khademhosseini.  “Applications of microscale technologies for Stem Cell Biology”, Cambridge Healthtech Institute’s Commercial Implications of Stem Cell Research: Recognizing the Reality,  San Francisco, CA (Feb. 2006).
+
-
 
+
-
  2005
+
-
12. G. Eng, A. Khademhosseini, J. Yeh, J. Fukuda, J. Blumling, J. Morin-Leisk, J. Gantz, R. Langer, J. Burdick.  “Photocrosslinkable hyaluronic acid for surface micropatterning”, 2005 Materials Research Society Fall Meeting, Boston, MA (Nov. 2005).
+
-
 
+
-
13. J. Yeh, A. Khademhosseini, , L. Ferreira,  J. Karp, J. Fukuda, G. Eng, J. Blumling, J. Morin-Leisk, J. Gantz, R. Langer, Jason Burdick.  “Microstructure mediated patterned co-cultures”, 2005 Materials Research Society Fall Meeting, Boston, MA (Nov. 2005).
+
-
 
+
-
14. J. Fukuda, A. Khademhosseini, J. Yeh, G. Eng, J.J. Cheng, O. Farokhzad, R. Langer. “Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components”, 2005 Materials Research Society Fall Meeting, Boston, MA (Nov. 2005). 
+
-
 
+
-
15. A. Khademhosseini, J. Fukuda, G. Eng, J. Yeh, J. Gantz,  J. Morin-Leisk, J. Blumling, R. Langer. “Patterned co-cultures of three-dimensional cell spheroids and support cells using microstructure patterned substrates”, 2005 Materials Research Society Fall Meeting, Boston, MA (Nov. 2005).
+
-
 
+
-
16. O. C. Farokhzad, S. Jon, A. Khademhosseini, J.J. Cheng, B. Teply, E. Levy-Nissenbaum, R. Langer.  “Cancer nanotechnology: drug encapsulated nanoparticle-aptamer bioconjugates for targeted delivery to prostate cancer cell”.  Federation of European Cancer Societies, Paris, France (Oct. 2005).
+
-
 
+
-
17. A. Khademhosseini,  O. C. Farokhzad, S. Jon, J.J. Cheng, B. Teply, E. Levy-Nissenbaum, R. Langer.  “Micro- and nanoscale technologies for cancer therapy”.  2005 MIT Center for Cancer Research Retreat , Water Valley, NH (Oct. 2005).
+
-
 
+
-
18. J. Cheng, B. Teply, I. Sherifi, E. Levy-Nissenbaum, A. Khademhosseini, R. Langer, O.C. Farokhzad; “Polymeric nanoparticle-aptamer bioconjugates as drug delivery vehicles for targeted prostate cancer therapy", 3rd International Nanomedicine and Drug Delivery Symposium, Baltimore, MD, (Sept. 26-27, 2005)
+
-
 
+
-
19. J. Fukuda, A. Khademhosseini, J. Yeh, G. Eng, R. Langer.  “Layer-by-layer deposition of HA and collagen for patterned cell co-cultures” CIMIT Symposium, Boston, MA (Sept. 2005).
+
-
 
+
-
20. S. Yang, J. Fukuda, A. Khademhosseini, J. Burdick, R. Langer.  “Fabrication of gradient hydrogels by a microfluidics/photopolymerization process”. CIMIT Symposium, Boston, MA (Sept. 2005).
+
-
 
+
-
21. J.M. Karp, L.S. Ferreira, A. Khademhosseini, A.H. Kwon, J. Yeh, R. Langer. “Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro.” Current Progress in Tissue Engineering”, Cambridge, MA (Sept. 2005).
+
-
 
+
-
22. A. Khademhosseini, G. Eng, J. Yeh, J. Karp, H. Kaji, J. Borenstein, O. Farokhzad, R. Langer. “Fabrication of Multiphenotye cell arrays within reversibly sealed microfluidic channels for high-throughput analysis”, MicroTAS  Symp. Proc. In press. Boston, MA (Oct. 2005).
+
-
 
+
-
23. P. Kim, D.–H. Kim, B. Kim, S. K. Choi, S. H. Lee, A. Khademhosseini, R. Langer, K. Y. Suh, “Fabrication of nanostructures of poly(ethylene glycol) and its application to protein and cell patterning” MicroTAS  Symp. Proc. In press. Boston, MA (Oct. 2005).
+
-
 
+
-
24. A. Khademhosseini*, J. Fukuda*, G. Eng, J. Yeh, O. Farokhzad, J.J. Cheng, R. Langer. “Layer-by-layer deposition of ionic biomolecules for patterned cellular co-cultures”, Biomedical Engineering Society Meeting, Baltimore, MD (Sept. 2005). 
+
-
 
+
-
25. J.M. Karp, L.S. Ferreira, A. Khademhosseini, A.H. Kwon, H. Seong, J. Yeh, R. Langer “Towards the differentiation of human embryonic stem cells for bone tissue engineering” HealthTech’s Institute Stem Cell Research Conference, Cambridge, MA (Aug. 2005).
+
-
 
+
-
26. A. Khademhosseini, J. Yeh, G. Eng, R. Langer. “Controlled embryoid body arrays using micropatterned substrates or non-adhesive microwells”, 2005 International Society of Stem cell Research Meeting, San Francisco, CA (June 2005).
+
-
 
+
-
27. K.Y. Suh, A. Khademhosseini, S.Y. Jon, R. Langer.  “Patterning inside microfluidic channels using a  soft lithographic method.” The 6th KSME-JSME Thermal and Fluids Engineering Conference, Jeju, KOREA (March 2005).
+
-
 
+
-
28. O. C. Farokhzad, A. Khademhosseini, S. Jon, A. Hermmann, C. Chin, R. Langer.  “Development of a Microfluidic Channels for Evaluating Targeted Drug Delivery Vehicles in-vitro”.  2005 International Anesthesia Research Society, Cleveland, OH (2005).
+
-
 
+
-
29. O. C. Farokhzad, S. Jon, A. Khademhosseini, T. Tran, D. LaVan, R. Langer; “Development and Evaluation of Nanoparticle-Aptamer Bioconjugates for Targeted Drug Delivery”. 2005 International Anesthesia Research Society, Cleveland, OH (2005).
+
-
 
+
-
  2004
+
-
30. A. Khademhosseini, J. Burdick, R. Langer.  “Fabrication of gradient hydrogels by a microfluidics/photopolymerization process”. 2004 Materials Research Society Fall Meeting, Boston, MA (Nov. 2004).
+
-
 
+
-
31. A. Khademhosseini, J. Yeh, S.Y. Jon, G. Eng, K.Y. Suh, J. Burdick, R. Langer.  “Molded polyethylene glycol microstructures for docking and shear protecting cells within microfluidic channels”. 2004 Materials Research Society Fall Meeting, Boston, MA (Nov. 2004).
+
-
 
+
-
32. K.Y. Suh, A. Khademhosseini, J.M. Yang, G. Eng, D. Berry, T.T. Tran, R. Langer. “Direct Immobilization and Patterning of Hyaluronic Acid on Hydrophilic Substrates”.  2004 Materials Research Society Fall Meeting, Boston, MA (Nov. 2004). 
+
-
 
+
-
33. S. Jaffar, K.T. Nam, A. Khademhosseini, R. Langer, A. Belcher. “Layer-by-layer modification and patterned electrostatic deposition of quantum dots” 2004 Materials Research Society Fall Meeting, Boston, MA (Nov. 2004). 
+
-
 
+
-
34. A. Khademhosseini, A. Mostasheri,  “An overview of socioeconomic characteristics of the Iranian-American community”  Iran: Future Prospect, gathering of young Iranian Scholars of North America, Palo Alto, CA (Oct. 2004) *Invited speaker*
+
-
 
+
-
35. A. Khademhosseini, J. Yeh, G. Eng, K.Y. Suh, S.Y. Jon, R. Langer. “Embryonic stem cell self-renewal and differentiation on patterned substrates”, 2004 International Society of Stem cell Research Meeting, Boston, MA (June 2004).
+
-
 
+
-
36. A. Khademhosseini, K.Y. Suh, S.Y. Jon, G. Chen, G. Eng, J. Yeh, R. Langer.  “A simple soft lithographic approach to pattern within microfluidic channels: Fabrication of arrays of cells or proteins within microfluidic channels”, 2004 Materials Research Society Spring Meeting, San Francisco, CA (April 2004).
+
-
 
+
-
37. A. Khademhosseini, K.Y. Suh, G. Eng, J. Yeh, J.M. Yang, S. Levenberg, R. Langer.  “Controlling stem cell microenvironments using surface patterning and patterned co-cultures”, Keystone symposia, Keystone, CO (March 2004).
+
-
 
+
-
38. J. Yeh, G. Eng, A. Khademhosseini, R. Langer, “Fabrication of multi-phenotype cell arrays within reversibly sealed microfluidic channels for high-throughput analysis”,  Harvard-MIT Division of Health Sciences and Technology (HST) Forum,  Boston, MA, 2004.
+
-
 
+
-
39. A. Khademhosseini, K.Y. Suh, S. J. Jon, G. Eng, J. Yeh, R. Langer, “Microscale approaches for controlling the cell microenvironment”, Proceedings for Canter for Cancer Research at MIT, Waterville Valley, NH., 2004.
+
-
 
+
-
40. A. Khademhosseini, K.Y. Suh, S. J. Jon, G. Eng, J. Yeh, R. Langer, “Controlling embryoid body formation using micropatterned surfaces”, Proceedings for MIT’s BPEC symposium, 2004.
+
-
 
+
-
41. J. Yeh, G. Eng, A. Khademhosseini, R. Langer, “Controlling stem cell microenvironment using surface patterning and patterned co-cultures”,  HST Forum,  Boston, MA, 2004.
+
-
 
+
-
  2003
+
-
42. A. Khademhosseini, S. Jon, K.Y. Suh, G. Eng, J. Yeh, T.T. Tran, R. Langer.  “Synthesis and application of a PEG-based copolymer for controlling surface topography and patterning proteins and cells”, NanoTech 2003 Conference, Switzerland. (Nov. 2003). 
+
-
 
+
-
43. O. Farokhzad, S. Jon, A. Khademhosseini, T.T. Tran, J. Toy, D. LaVan, R. Langer “Development of PEGylated PLA Nanoparticle-Aptamer Bioconjugates for Targeted Drug Delivery to Prostate Cancer Cells”, 7th annual US-Japan Drug Delivery Conference, Hawaii, USA. (Dec. 2003).
+
-
 
+
-
44. K.Y. Suh, A. Khademhosseini, S.Y. Jon, R. Langer.  “Patterned PEG hydrogels for drug delivery”, 7th annual US-Japan Drug Delivery Conference, Hawaii, USA. (Dec. 2003).
+
-
 
+
-
45. K.Y. Suh, J. Seong, A.  Khademhosseini, P.E.  Laibinis, R. Langer.  “Construction of non-biofouling surfaces by polymeric self-assembled monolayer”. 2003 MRS Fall Meeting, Boston, MA (Dec. 2003).
+
-
 
+
-
46. A. Khademhosseini, K.Y. Suh, S. J. Jon, R. Langer, “Controlled microenvironments based on microfluidics and microfabrication for controlling cell-microenvironment interactions”, Proceedings for MIT’s BPEC symposium, 2003.
+
-
 
+
-
  2001
+
-
47. S. Jon, J. Seong, A. Khademhosseini, T.T. Tran, P.E. Laibinis, R. Langer. “Construction of non-biofouling surfaces by polymeric self-assembled monolayer”.  AIChE meeting, San Francisco, CA (Nov. 2003).
+
-
 
+
-
48. A. Khademhosseini, C.Y. Ito, M.V. Sefton, W.L. Stanford, P.W. Zandstra. “In vitro differentiation of bone marrow derived Lin- CD45+ sca-1+ c-kit+ cells into hepatocyte-like cells”,  Blood  98 (11):548a (2001).
+
-
 
+
-
49. A. Khademhosseini, W.L. Stanford, M.V. Sefton, P.W. Zandstra. “In vitro differentiation of phenotypically defined bone marrow derived progenitors in liver-like microenvironments”, Annals of Biomedical Engineering. 29 (S1): S-152 (2001). 
+
-
 
+
-
50. A. Khademhosseini, W.L. Stanford, M.V. Sefton, P.W. Zandstra. “Endoderm differentiation of murine bone marrow derived cells in vitro”, Proceedings of the 21st Annual Great Lakes Mammalian Development Meeting (April 2001).
+
-
 
+
-
51. J.M. Karp, A. Khademhosseini, et al. "Biomaterials Education from Students’ Perspective", Transactions of the 27th annual Meeting of the Society for Biomaterials (April 2001).
+
-
 
+
-
52. A. Khademhosseini, W.L. Stanford, M.V. Sefton, P.W. Zandstra. “Endoderm differentiation of murine bone marrow derived cells in vitro”, Proceedings of the IBBME Scientific Day.  (2001).
+
-
 
+
-
53. A. Khademhosseini, D. Lavan, S. Levenberg, J. Hsiao, A. Kiselyuk, R. Langer, “Generation of controlled microenvironments to study embryonic stem cell differentiation and self-renewal”, Proceedings for MIT’s BPEC symposium, (2002).
+
-
2000
+
==Patents / Technology disclosures:==
-
54. M.V. Sefton, A. Khademhosseini, “Engineering Biology: an elective course for first year engineering”, Proceedings of Whitaker Foundation Educational Summit (Dec. 2000).
+
#A. Khademhosseini, J. Karp, D. Berry, R. Langer, “Tooth Whitening”, Submitted to the MIT Technology Licensing Office (March. 2006).
 +
#A. Khademhosseini, J. Karp, L. Ferreira, Y. Yoon, R. Langer, “Highly efficient dessicants”, Submitted to the MIT Technology Licensing Office (March. 2006).
 +
#A. Khademhosseini, J. Karp, O. Farokhzad, R. Langer, “Microencapsulation of cells within shape-controlled biomaterials as building blocks for engineering tissues and organs.”, Submitted to the MIT Technology Licensing Office (Jan. 2006).
 +
#A. Khademhosseini, J. Karp, G. Eng, J. Yeh, R. Langer, “Template based tissue engineering”, Submitted to the MIT Technology Licensing Office (Sept. 2005).
 +
#A. Khademhosseini, J. Karp, M. Moore, R. Langer, “A Platform Technology Based on Bioactive Hydrogels”, Submitted to the MIT Technology Licensing Office (Aug. 2005).
 +
#A. Khademhosseini, J. Yeh, G. Eng, J. Borenstein, R. Langer.  “Multi-phenotype cellular arrays within microfluidic channels”, Submitted to the MIT Technology Licensing Office (Feb. 2005).
 +
#A. Khademhosseini, O. Farokhzad, R. Langer, “High Throughput Synthesis of Functionalized Materials”, filed to USA Patent Office (Dec. 2005) -  Patent Pending.
 +
#A. Khademhosseini, J. Karp, L.S. Ferreira, R. Langer “Improved differentiation of human embryonic stem cells to osteogenic cells” filed to USA Patent Office (Sept. 2005) -  Patent Pending.
 +
#A. Khademhosseini, K.Y. Suh, S.Y. Jon, R. Langer.  “Patterned surfaces and polymeric microstructures within robust microfluidic channels” filed to USA Patent Office (Feb. 2005) - Patent Pending.
 +
#A. Khademhosseini, K.Y. Suh, D. Berry, R. Sasisekharan, R. Langer.  “Deposition of glycosaminoglycans to form biologically active surfaces” filed to USA Patent Office (Sept. 2004) - Patent Pending.
-
55. A. Khademhosseini, M. May, M.V. Sefton "Conformal Coating of Mammalian Cells Immobilized to Polystyrene Beads", Proceedings for Canadian Society Chemical Engineers Conference (Oct. 2000).
+
==Conference Proceedings / Abstracts:==
 +
===2006===
 +
#A. Khademhosseini. “Microscale technologies in tissue engineering”, Digital Fabrication Conference, Denver, CO (Sept. 2006). (Keynote speaker)
 +
#A. Khademhosseini, L.S. Ferreira, J.M. Karp, J. Blumling III, J. Yeh, J. Fukuda, G. Eng, J. Gantz, and R. Langer. “Micropatterned Co-cultures of Human Embryonic Stem Cells with Murine Embryonic Fibroblasts”, 2006 International Society of Stem cell Research Meeting, Toronto, ON (June 2006).
 +
#J. Yeh, J. M. Karp, G. Eng, J. Fukuda, J. Blumling, R. Langer, A. Khademhosseini.  “Controlling size, shape, and homogeneity of embryonic stem cell aggregates and embryoid bodies within poly(ethylene glycol) microwells”, 2006 International Society of Stem cell Research Meeting, Toronto, ON (June 2006).
 +
#Y. Ling, J. Yeh, J. M. Karp, A. Chandawarkar, J. Gantz, R. Langer, A. Khademhosseini.  “Shape and size-controlled photocrosslinkable microgels for encapsulation of embryonic stem cells”, 2006 International Society of Stem cell Research Meeting, Toronto, ON (June 2006).
 +
#J.M. Karp, L.S. Ferreira; A. Khademhosseini, A. Kwan, J. Yeh, R. Langer. “Exclusion of the embryoid body step improves the differentiation efficiency of human embryonic stem cells into osteoblasts”, 2006 International Society of Stem cell Research Meeting, Toronto, ON (June 2006).
 +
#J.M. Karp, A. Khademhosseini, L.S. Ferreira, A. Kwan, J. Yeh, R. Langer. “Micropatterned Co-cultures of Human Embryonic Stem Cells with Murine Embryonic Fibroblasts”, Canadian Society for Biomaterials Annual Meeting, Calgary, AL (May 26th-28th 2006)
 +
#J.M. Karp, L.S. Ferreira, A. Khademhosseini, A.. Kwan, O. Farokhzad, J. Yeh, R. Langer. “Amplification of Osteogenic Cells from Human Embryonic Stem Cells”, Society for Biomaterials Meeting, Pittsburgh, PA (March, 2006).
 +
#J.M. Karp, L.S. Ferreira, A. Khademhosseini, R. Li, N. Choodnovskiy, K. Yan, R. Langer. “Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro”, 52nd Annual Orthopedic Research Society, Chicago, IL (March, 2006).
 +
#A. Khademhosseini, G. Eng, J. Yeh, J. Fukuda, J. Blumling III, J.M. Karp, R. Langer,  J.A. Burdick.  “Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment”, Society for Biomaterials Meeting, Pittsburgh, PA (March, 2006).
 +
#A. Khademhosseini.  “Academic position search:  Perspectives from a recent faculty candidate”, Society for Biomaterials Meeting, Pittsburgh, PA (March, 2006). (Invited speaker)
 +
#A. Khademhosseini.  “Applications of microscale technologies for Stem Cell Biology”, Cambridge Healthtech Institute’s Commercial Implications of Stem Cell Research: Recognizing the Reality,  San Francisco, CA (Feb. 2006).
 +
===2005===
 +
#G. Eng, A. Khademhosseini, J. Yeh, J. Fukuda, J. Blumling, J. Morin-Leisk, J. Gantz, R. Langer, J. Burdick.  “Photocrosslinkable hyaluronic acid for surface micropatterning”, 2005 Materials Research Society Fall Meeting, Boston, MA (Nov. 2005).
 +
#J. Yeh, A. Khademhosseini, , L. Ferreira,  J. Karp, J. Fukuda, G. Eng, J. Blumling, J. Morin-Leisk, J. Gantz, R. Langer, Jason Burdick.  “Microstructure mediated patterned co-cultures”, 2005 Materials Research Society Fall Meeting, Boston, MA (Nov. 2005).
 +
#J. Fukuda, A. Khademhosseini, J. Yeh, G. Eng, J.J. Cheng, O. Farokhzad, R. Langer. “Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components”, 2005 Materials Research Society Fall Meeting, Boston, MA (Nov. 2005). 
 +
#A. Khademhosseini, J. Fukuda, G. Eng, J. Yeh, J. Gantz,  J. Morin-Leisk, J. Blumling, R. Langer. “Patterned co-cultures of three-dimensional cell spheroids and support cells using microstructure patterned substrates”, 2005 Materials Research Society Fall Meeting, Boston, MA (Nov. 2005).
 +
#O. C. Farokhzad, S. Jon, A. Khademhosseini, J.J. Cheng, B. Teply, E. Levy-Nissenbaum, R. Langer.  “Cancer nanotechnology: drug encapsulated nanoparticle-aptamer bioconjugates for targeted delivery to prostate cancer cell”.  Federation of European Cancer Societies, Paris, France (Oct. 2005).
 +
#A. Khademhosseini,  O. C. Farokhzad, S. Jon, J.J. Cheng, B. Teply, E. Levy-Nissenbaum, R. Langer.  “Micro- and nanoscale technologies for cancer therapy”.  2005 MIT Center for Cancer Research Retreat , Water Valley, NH (Oct. 2005).
 +
#J. Cheng, B. Teply, I. Sherifi, E. Levy-Nissenbaum, A. Khademhosseini, R. Langer, O.C. Farokhzad; “Polymeric nanoparticle-aptamer bioconjugates as drug delivery vehicles for targeted prostate cancer therapy", 3rd International Nanomedicine and Drug Delivery Symposium, Baltimore, MD, (Sept. 26-27, 2005)
 +
#J. Fukuda, A. Khademhosseini, J. Yeh, G. Eng, R. Langer.  “Layer-by-layer deposition of HA and collagen for patterned cell co-cultures” CIMIT Symposium, Boston, MA (Sept. 2005).
 +
#S. Yang, J. Fukuda, A. Khademhosseini, J. Burdick, R. Langer.  “Fabrication of gradient hydrogels by a microfluidics/photopolymerization process”. CIMIT Symposium, Boston, MA (Sept. 2005).
 +
#J.M. Karp, L.S. Ferreira, A. Khademhosseini, A.H. Kwon, J. Yeh, R. Langer. “Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro.” Current Progress in Tissue Engineering”, Cambridge, MA (Sept. 2005).
 +
#A. Khademhosseini, G. Eng, J. Yeh, J. Karp, H. Kaji, J. Borenstein, O. Farokhzad, R. Langer. “Fabrication of Multiphenotye cell arrays within reversibly sealed microfluidic channels for high-throughput analysis”, MicroTAS  Symp. Proc. In press. Boston, MA (Oct. 2005).
 +
#P. Kim, D.–H. Kim, B. Kim, S. K. Choi, S. H. Lee, A. Khademhosseini, R. Langer, K. Y. Suh, “Fabrication of nanostructures of poly(ethylene glycol) and its application to protein and cell patterning” MicroTAS  Symp. Proc. In press. Boston, MA (Oct. 2005).
 +
#A. Khademhosseini*, J. Fukuda*, G. Eng, J. Yeh, O. Farokhzad, J.J. Cheng, R. Langer. “Layer-by-layer deposition of ionic biomolecules for patterned cellular co-cultures”, Biomedical Engineering Society Meeting, Baltimore, MD (Sept. 2005). 
 +
#J.M. Karp, L.S. Ferreira, A. Khademhosseini, A.H. Kwon, H. Seong, J. Yeh, R. Langer “Towards the differentiation of human embryonic stem cells for bone tissue engineering” HealthTech’s Institute Stem Cell Research Conference, Cambridge, MA (Aug. 2005).
 +
#A. Khademhosseini, J. Yeh, G. Eng, R. Langer. “Controlled embryoid body arrays using micropatterned substrates or non-adhesive microwells”, 2005 International Society of Stem cell Research Meeting, San Francisco, CA (June 2005).
 +
#K.Y. Suh, A. Khademhosseini, S.Y. Jon, R. Langer.  “Patterning inside microfluidic channels using a  soft lithographic method.” The 6th KSME-JSME Thermal and Fluids Engineering Conference, Jeju, KOREA (March 2005).
 +
#O. C. Farokhzad, A. Khademhosseini, S. Jon, A. Hermmann, C. Chin, R. Langer.  “Development of a Microfluidic Channels for Evaluating Targeted Drug Delivery Vehicles in-vitro”.  2005 International Anesthesia Research Society, Cleveland, OH (2005).
 +
#O. C. Farokhzad, S. Jon, A. Khademhosseini, T. Tran, D. LaVan, R. Langer; “Development and Evaluation of Nanoparticle-Aptamer Bioconjugates for Targeted Drug Delivery”. 2005 International Anesthesia Research Society, Cleveland, OH (2005).
-
56. A. Khademhosseini, M. May, M.V. Sefton. “A Novel Geometric Configuration for Conformal Coating of Mammalian Cells”, Proceedings of the IBBME Scientific Day (2000).
+
===2004===
 +
#A. Khademhosseini, J. Burdick, R. Langer.  “Fabrication of gradient hydrogels by a microfluidics/photopolymerization process”. 2004 Materials Research Society Fall Meeting, Boston, MA (Nov. 2004).
 +
#A. Khademhosseini, J. Yeh, S.Y. Jon, G. Eng, K.Y. Suh, J. Burdick, R. Langer.  “Molded polyethylene glycol microstructures for docking and shear protecting cells within microfluidic channels”. 2004 Materials Research Society Fall Meeting, Boston, MA (Nov. 2004).
 +
#K.Y. Suh, A. Khademhosseini, J.M. Yang, G. Eng, D. Berry, T.T. Tran, R. Langer. “Direct Immobilization and Patterning of Hyaluronic Acid on Hydrophilic Substrates”.  2004 Materials Research Society Fall Meeting, Boston, MA (Nov. 2004). 
 +
#S. Jaffar, K.T. Nam, A. Khademhosseini, R. Langer, A. Belcher. “Layer-by-layer modification and patterned electrostatic deposition of quantum dots” 2004 Materials Research Society Fall Meeting, Boston, MA (Nov. 2004). 
 +
#A. Khademhosseini, A. Mostasheri,  “An overview of socioeconomic characteristics of the Iranian-American community”  Iran: Future Prospect, gathering of young Iranian Scholars of North America, Palo Alto, CA (Oct. 2004) *Invited speaker*
 +
#A. Khademhosseini, J. Yeh, G. Eng, K.Y. Suh, S.Y. Jon, R. Langer. “Embryonic stem cell self-renewal and differentiation on patterned substrates”, 2004 International Society of Stem cell Research Meeting, Boston, MA (June 2004).
 +
#A. Khademhosseini, K.Y. Suh, S.Y. Jon, G. Chen, G. Eng, J. Yeh, R. Langer.  “A simple soft lithographic approach to pattern within microfluidic channels: Fabrication of arrays of cells or proteins within microfluidic channels”, 2004 Materials Research Society Spring Meeting, San Francisco, CA (April 2004).
 +
#A. Khademhosseini, K.Y. Suh, G. Eng, J. Yeh, J.M. Yang, S. Levenberg, R. Langer.  “Controlling stem cell microenvironments using surface patterning and patterned co-cultures”, Keystone symposia, Keystone, CO (March 2004).
 +
#J. Yeh, G. Eng, A. Khademhosseini, R. Langer, “Fabrication of multi-phenotype cell arrays within reversibly sealed microfluidic channels for high-throughput analysis”,  Harvard-MIT Division of Health Sciences and Technology (HST) Forum,  Boston, MA, 2004.
 +
#A. Khademhosseini, K.Y. Suh, S. J. Jon, G. Eng, J. Yeh, R. Langer, “Microscale approaches for controlling the cell microenvironment”, Proceedings for Canter for Cancer Research at MIT, Waterville Valley, NH., 2004.
 +
#A. Khademhosseini, K.Y. Suh, S. J. Jon, G. Eng, J. Yeh, R. Langer, “Controlling embryoid body formation using micropatterned surfaces”, Proceedings for MIT’s BPEC symposium, 2004.
 +
#J. Yeh, G. Eng, A. Khademhosseini, R. Langer, “Controlling stem cell microenvironment using surface patterning and patterned co-cultures”,  HST Forum,  Boston, MA, 2004.
 +
===2003===
 +
#A. Khademhosseini, S. Jon, K.Y. Suh, G. Eng, J. Yeh, T.T. Tran, R. Langer.  “Synthesis and application of a PEG-based copolymer for controlling surface topography and patterning proteins and cells”, NanoTech 2003 Conference, Switzerland. (Nov. 2003). 
 +
#O. Farokhzad, S. Jon, A. Khademhosseini, T.T. Tran, J. Toy, D. LaVan, R. Langer “Development of PEGylated PLA Nanoparticle-Aptamer Bioconjugates for Targeted Drug Delivery to Prostate Cancer Cells”, 7th annual US-Japan Drug Delivery Conference, Hawaii, USA. (Dec. 2003).
 +
#K.Y. Suh, A. Khademhosseini, S.Y. Jon, R. Langer.  “Patterned PEG hydrogels for drug delivery”, 7th annual US-Japan Drug Delivery Conference, Hawaii, USA. (Dec. 2003).
 +
#K.Y. Suh, J. Seong, A.  Khademhosseini, P.E.  Laibinis, R. Langer.  “Construction of non-biofouling surfaces by polymeric self-assembled monolayer”. 2003 MRS Fall Meeting, Boston, MA (Dec. 2003).
 +
#A. Khademhosseini, K.Y. Suh, S. J. Jon, R. Langer, “Controlled microenvironments based on microfluidics and microfabrication for controlling cell-microenvironment interactions”, Proceedings for MIT’s BPEC symposium, 2003.
 +
===2001===
 +
#S. Jon, J. Seong, A. Khademhosseini, T.T. Tran, P.E. Laibinis, R. Langer. “Construction of non-biofouling surfaces by polymeric self-assembled monolayer”.  AIChE meeting, San Francisco, CA (Nov. 2003).
 +
#A. Khademhosseini, C.Y. Ito, M.V. Sefton, W.L. Stanford, P.W. Zandstra. “In vitro differentiation of bone marrow derived Lin- CD45+ sca-1+ c-kit+ cells into hepatocyte-like cells”,  Blood  98 (11):548a (2001).
 +
#A. Khademhosseini, W.L. Stanford, M.V. Sefton, P.W. Zandstra. “In vitro differentiation of phenotypically defined bone marrow derived progenitors in liver-like microenvironments”, Annals of Biomedical Engineering. 29 (S1): S-152 (2001). 
 +
#A. Khademhosseini, W.L. Stanford, M.V. Sefton, P.W. Zandstra. “Endoderm differentiation of murine bone marrow derived cells in vitro”, Proceedings of the 21st Annual Great Lakes Mammalian Development Meeting (April 2001).
 +
#J.M. Karp, A. Khademhosseini, et al. "Biomaterials Education from Students’ Perspective", Transactions of the 27th annual Meeting of the Society for Biomaterials (April 2001).
 +
#A. Khademhosseini, W.L. Stanford, M.V. Sefton, P.W. Zandstra. “Endoderm differentiation of murine bone marrow derived cells in vitro”, Proceedings of the IBBME Scientific Day.  (2001).
 +
#A. Khademhosseini, D. Lavan, S. Levenberg, J. Hsiao, A. Kiselyuk, R. Langer, “Generation of controlled microenvironments to study embryonic stem cell differentiation and self-renewal”, Proceedings for MIT’s BPEC symposium, (2002).
 +
===2000===
 +
#M.V. Sefton, A. Khademhosseini, “Engineering Biology: an elective course for first year engineering”, Proceedings of Whitaker Foundation Educational Summit (Dec. 2000).
 +
#A. Khademhosseini, M. May, M.V. Sefton "Conformal Coating of Mammalian Cells Immobilized to Polystyrene Beads", Proceedings for Canadian Society Chemical Engineers Conference (Oct. 2000).
 +
#A. Khademhosseini, M. May, M.V. Sefton. “A Novel Geometric Configuration for Conformal Coating of Mammalian Cells”, Proceedings of the IBBME Scientific Day (2000).

Current revision

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Contents

Journals Articles:

In preparation

  1. B. Murtuza, R. Langer, A. Khademhosseini. “Micropatterning and microfluidics for cardiac tissue engineering” (In preparation).
  2. J. Yeh, A. Khademhosseini, J. Fukuda, J. Karp, G. Eng, R. Langer. “Microstructure mediated patterned co-cultures” (In preparation).

2006

  1. A. Khademhosseini*, L. Ferreira*, J. Yeh, J. Blumling, J. Fukuda, G. Eng, R. Langer. “Co-cultures of human embryonic stem cells and murine embryonic feeder cells on microwell patterned surfaces” Biomaterials (Submitted).
  2. Y. Ling*, J. Yeh*, J. Gantz, J. Yeh, G. Eng, J. Fukuda, R. Langer, A. Khademhosseini. “Micromolding of photocrosslinkable hydrogels for cell encapsulation” Tissue Engineering (Submitted).
  3. J. Karp*, J. Yeh*, G. Eng, J. Fukuda, J. Blumling, K.Y. Suh, J. Cheng, J. Borenstein, R. Langer, A. Khademhosseini. “Controlling size, shape and homogeneity of embryoid bodies using polymeric microwells” Stem cells (Submitted).
  4. K. Y. Suh, A. Khademhosseini, S.Y. Jon, R. Langer. “Confinement of an individual M13 virus within a poly(ethylene glycol) nanowells” Nanoletters (Submitted)
  5. A. Khademhosseini, J. Karp, C. Bettinger, J. Yeh, Y. Ling, J. Borenstein, J. Fukuda, R. Langer. “Biomaterials and microscale technologies: building on each other to advance biomedical applications” Journal of Biomaterials Science: Polymer Edition (Submitted)
  6. P. Kim, H.E. Jeong, A. Khademhosseini, K.Y. Suh “Fabrication of non-biofouling polyethylene glycol (PEG) micro- to nanochannels by ultraviolet-assisted irreversible sealing” Advanced Materials (Submitted).
  7. J. Fukuda, A. Khademhosseini, Y. Yeo, J. Yeh, X. Yang, G. Eng, J. Blumling, C.F. Wang, D.S. Kohane, R. Langer. “Micromolding of photocrosslinkable chitosan hydrogel for spheroid microarray and co-cultures” Biomaterials (Submitted).
  8. A. Khademhosseini, J. Yeh, G. Eng, S. Kucharczyk, R. Langer, G. Vunjak-Novakovic, M. Radisic “Microfluidic patterning for fabrication of contractile cardiac organoids” Biomedical Microdevices (Submitted).
  9. A. Khademhosseini, G. Eng, J. Yeh, J. Fukuda, J. Blumling, R. Langer, J. Burdick. “Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment” Journal of Biomedical Materials Research: Part B Applied Biomaterials In Press (2006).
  10. A. Khademhosseini, R. Langer. “Nanobiotechnolgy for Tissue Engineering and Drug Delivery” Chemical Engineering Progress In press (2006).
  11. J. Cheng, B. Teply, C. Yim, S.Y. Jeong, I. Sherifi, S. Jon, A. Khademhosseini, O.C. Farokhzad, R. Langer. “Magnetite-PLGA-Insulin Microparticles: Novel Magnetically Responsive Vehicles for Oral Protein Delivery” Pharmaceutical Research In press (2006).
  12. N. Peppas, Z. Hilt, A. Khademhosseini, R. Langer. “Hydrogels in Biomedical applications: From fundamentals to nanobiotechnology”. Advanced Materials In press (2006).
  13. A. Khademhosseini, R. Langer, J. Borenstein, J. Vacanti. “Microscale Technologies for Tissue Engineering and Biology” Proceedings of National Academy of Sciences USA 103:2480-2487 (2006).

2005

  1. J.M. Karp, L.S. Ferreira, A. Khademhosseini, A.H. Kwon, J. Yeh, R. Langer “Cultivation of Human Embryonic Stem Cells without the Embryoid Body step enhances osteogenesis in vitro” Stem Cells In press (2005)
  2. A. Khademhosseini*, J. Fukuda*, J. Yeh, G. Eng, R. Langer. “Layer-by-layer deposition of HA and collagen for patterned cell co-cultures” Biomaterials 27(8): 1479-1486 (2006).
  3. A. Khademhosseini, M.H. May, M.V. Sefton. “Conformal Coating of Mammalian Cells Immobilized onto Magnetically Driven Beads” Tissue Engineering 11(11) 1797-1806 (2005).
  4. A. Khademhosseini, J. Yeh, G. Eng, H. Kazi, J. Borenstein, J. Karp, O. Farokhzad, R. Langer. “Cell docking inside microwells within reversibly sealed microfluidic channels for multiphenotype cellular arrays” Lab on a Chip 5(12):1380-6 (2005). (Cover feature – also featured as a news article in Analytical Chemistry 78(3): 642 (2006)).
  5. A. Khademhosseini. “Chips to Hits: microarrays and microfluidic technologies for high-throughput analysis and drug discovery” Expert Reviews of Molecular Diagnostics 5(6): 843-846 (2005).
  6. P. Kim, D.–H. Kim, B. Kim, S. K. Choi, S. H. Lee, A. Khademhosseini, R. Langer, K. Y. Suh, “Fabrication of nanostructures of poly(ethylene glycol) for protein adsorption and cell adhesion” Nanotechnology 16: 2420-2426 (2005).
  7. A. Khademhosseini*, O.C. Farokhzad*, S.Y. Jon, A. Hermmann, J.J. Cheng, C. Chin, A. Kiselyuk, G. Eng, B. Teply, R. Langer,. “Microfluidic System for Studying the Interaction of Nanoparticles and Microparticles with Cells” Analytical Chemistry 77(17): 5453-5459 (2005)
  8. K.Y. Suh, J.M. Yang, A. Khademhosseini, D. Berry, T.T. Tran, H. Park, and R. Langer “Characterization of Chemisorbed Hyaluronic Acid Directly Immobilized on Solid Substrates”, Journal of Biomedical Materials Research: Part B Applied Biomaterials 72(B): 292-298 (2005).

2004

  1. O.C. Farokhzad, S.Y. Jon, A. Khademhosseini, T.T. Tran, D. LaVan, R. Langer. “Nanoparticle-Aptamer Bioconjugates: A New Approach for Targeting Prostate Cancer Cells” Cancer Research 64(21):7668-7672 (2004).
  2. K.Y. Suh, K. Yoon, H.H. Lee, A. Khademhosseini, R. Langer. “Solventless ordering of colloidal particles through the applicant of patterned elastomeric stamps under pressure”, Applied Physics Letters 85 (13): 2643-2645 (2004).
  3. K. Y. Suh, A. Khademhosseini, P.J. Yoo, R. Langer. “Patterning and separating infected bacteria using host-parasite and virus-antibody interactions” Biomedical Microdevices 6 (3):223-229 (2004).
  4. S. Jaffar, K.T. Nam, A. Khademhosseini, J. Xing, R. Langer, A. Belcher. “Layer-by-layer surface modification and patterned electrostatic deposition of quantum dots” Nano Letters 4(8); 1421-1425 (2004).
  5. A. Khademhosseini, J. Yeh, S.Y. Jon, G. Eng, K.Y. Suh, J. Burdick, R. Langer. “Molded poly(ethylene glycol) microstructures for docking and shear protecting cells within microfluidic channels” Lab on a chip 4; 425 - 430 (2004).
  6. K.Y. Suh, A. Khademohsseini, G. Eng, R. Langer. “Single nanocrystal arrays on patterned poly(ethylene glycol) copolymer microstructures using selective wetting and drying” Langmuir 20 (15): 6080-6084 (2004).
  7. A. Khademhosseini, K.Y. Suh, S.Y. Jon, G. Chen, G. Eng, J. Yeh, R. Langer. “A soft lithographic approach for fabricating patterned microfluidic channels” Analytical Chemistry 76 (13): 3675-3681 (2004).
  8. A. Khademhosseini*, J. Burdick*, R. Langer. “Fabrication of Gradient Hydrogels Using a Microfluidics/Photopolymerization Process”. Langmuir 20 (13): 5153-5156 (2004).
  9. K.Y. Suh, A. Khademhosseini, J.M. Yang, T.T. Tran, G. Eng, and R. Langer “Soft lithographic patterning of hyaluronic acid on solid substrates using molding and printing”, Advanced Materials 16 (7): 584-588 (2004).
  10. A. Khademhosseini, K.Y. Suh, J.M. Yang, G. Eng, J. Yeh, S. Levenberg, R. Langer. “Layer-by-layer deposition of hyaluronic acid and poly-L-lysine for patterned cell co-cultures”, Biomaterials, 25: 3583-3592 (2004).
  11. K.Y. Suh, J. Seong, A. Khademhosseini, P. E. Laibinis, R. Langer. “Patterned deposition of proteins and cells using a molding technique”. Biomaterials, 25: 557-563 (2004).

2003

  1. A. Khademhosseini, S. Jon, K.Y. Suh, G. Eng, J. Yeh, T.T. Tran, R. Langer. “Direct patterning of cell and protein resistant polymeric monolayer and microstructures”. Advanced Materials 15 (23): 1995-2000 (2003).
  2. S. Jon, J. Seong, A. Khademhosseini, T.T. Tran, P.E. Laibinis, R. Langer. “Construction of non-biofouling surfaces by polymeric self-assembled monolayers”. Langmuir, 19 (15): 9989-9993 (2003).
  • denotes equal contribution by authors.

Book Chapters:

  1. J. Karp, L. Ferreira, A. Khademhosseini, R. Langer. “in vitro differentiation of Human ES cells down osteogenic pathways” in “Embryonic Stem Cells: a practical handbook”, Editors, Stephen Sullivan, Kevin Eggan and Chad Cowan, John Wiley & Sons (2006) (In preparation)
  2. A. Khademhosseini, Y. Ling, J. Karp, R. Langer. “Nanofabricated structures for tissue engineering”. Nanobiotechnology: Concepts, Applications and Perspectives”, Editors, Chad A. Mirkin and Christof M. Neimeyer, Wiley-VCH (2006).
  3. A. Khademhosseini, S. Gretchet-Nir, J. Karp, L. Ferreira, G. Vunjak-Novakovic, R. Langer. “Embryonic stem cells in tissue engineering”. Principles of Tissue Engineering, 3rd Edition, Editor: Robert Lanza, Academic Press (2006).
  4. S. Levenberg, A. Khademhosseini, R. Langer. “Embryonic stem cells and tissue engineering”. In “Handbook of Stem Cells”, Editors: Editors Doug Melton, James Thomson, John Gearhart, Brigid Hogan, Ron McKay, Roger Pedersen, Mike West and Robert Lanza, Academic Press (2004).
  5. S. Levenberg, A. Khademhosseini, R. Langer. “Embryonic stem cells and tissue engineering”. In “Essentials of Stem Cell Biology”, Editors: Robert Lanza, John Gearhart, Brigid Hogan, Douglas Melton, Roger Pedersen, James Thomson, E. Donnall Thomas, Irving Weissman, Michael West, Academic Press (2004).
  6. S. Levenberg, A. Khademhosseini, M. McDonald, J. Fuller, R. Langer. “Methods of (human) embryonic stem cell culture”. Chapter 3 in “Culture of cells for tissue engineering”, Editors I. Freshney and G. Vunjak-Novakovic, Humana Press (2004).
  7. A. Khademhosseini, P.W. Zandstra. “Engineering the in vitro cellular microenvironment for the control and manipulation of adult stem cell responses”. In “Adult stem cells”, Editor K. Turksen, Ch. 15, p 289-314, Humana Press (2003).

Patents / Technology disclosures:

  1. A. Khademhosseini, J. Karp, D. Berry, R. Langer, “Tooth Whitening”, Submitted to the MIT Technology Licensing Office (March. 2006).
  2. A. Khademhosseini, J. Karp, L. Ferreira, Y. Yoon, R. Langer, “Highly efficient dessicants”, Submitted to the MIT Technology Licensing Office (March. 2006).
  3. A. Khademhosseini, J. Karp, O. Farokhzad, R. Langer, “Microencapsulation of cells within shape-controlled biomaterials as building blocks for engineering tissues and organs.”, Submitted to the MIT Technology Licensing Office (Jan. 2006).
  4. A. Khademhosseini, J. Karp, G. Eng, J. Yeh, R. Langer, “Template based tissue engineering”, Submitted to the MIT Technology Licensing Office (Sept. 2005).
  5. A. Khademhosseini, J. Karp, M. Moore, R. Langer, “A Platform Technology Based on Bioactive Hydrogels”, Submitted to the MIT Technology Licensing Office (Aug. 2005).
  6. A. Khademhosseini, J. Yeh, G. Eng, J. Borenstein, R. Langer. “Multi-phenotype cellular arrays within microfluidic channels”, Submitted to the MIT Technology Licensing Office (Feb. 2005).
  7. A. Khademhosseini, O. Farokhzad, R. Langer, “High Throughput Synthesis of Functionalized Materials”, filed to USA Patent Office (Dec. 2005) - Patent Pending.
  8. A. Khademhosseini, J. Karp, L.S. Ferreira, R. Langer “Improved differentiation of human embryonic stem cells to osteogenic cells” filed to USA Patent Office (Sept. 2005) - Patent Pending.
  9. A. Khademhosseini, K.Y. Suh, S.Y. Jon, R. Langer. “Patterned surfaces and polymeric microstructures within robust microfluidic channels” filed to USA Patent Office (Feb. 2005) - Patent Pending.
  10. A. Khademhosseini, K.Y. Suh, D. Berry, R. Sasisekharan, R. Langer. “Deposition of glycosaminoglycans to form biologically active surfaces” filed to USA Patent Office (Sept. 2004) - Patent Pending.

Conference Proceedings / Abstracts:

2006

  1. A. Khademhosseini. “Microscale technologies in tissue engineering”, Digital Fabrication Conference, Denver, CO (Sept. 2006). (Keynote speaker)
  2. A. Khademhosseini, L.S. Ferreira, J.M. Karp, J. Blumling III, J. Yeh, J. Fukuda, G. Eng, J. Gantz, and R. Langer. “Micropatterned Co-cultures of Human Embryonic Stem Cells with Murine Embryonic Fibroblasts”, 2006 International Society of Stem cell Research Meeting, Toronto, ON (June 2006).
  3. J. Yeh, J. M. Karp, G. Eng, J. Fukuda, J. Blumling, R. Langer, A. Khademhosseini. “Controlling size, shape, and homogeneity of embryonic stem cell aggregates and embryoid bodies within poly(ethylene glycol) microwells”, 2006 International Society of Stem cell Research Meeting, Toronto, ON (June 2006).
  4. Y. Ling, J. Yeh, J. M. Karp, A. Chandawarkar, J. Gantz, R. Langer, A. Khademhosseini. “Shape and size-controlled photocrosslinkable microgels for encapsulation of embryonic stem cells”, 2006 International Society of Stem cell Research Meeting, Toronto, ON (June 2006).
  5. J.M. Karp, L.S. Ferreira; A. Khademhosseini, A. Kwan, J. Yeh, R. Langer. “Exclusion of the embryoid body step improves the differentiation efficiency of human embryonic stem cells into osteoblasts”, 2006 International Society of Stem cell Research Meeting, Toronto, ON (June 2006).
  6. J.M. Karp, A. Khademhosseini, L.S. Ferreira, A. Kwan, J. Yeh, R. Langer. “Micropatterned Co-cultures of Human Embryonic Stem Cells with Murine Embryonic Fibroblasts”, Canadian Society for Biomaterials Annual Meeting, Calgary, AL (May 26th-28th 2006)
  7. J.M. Karp, L.S. Ferreira, A. Khademhosseini, A.. Kwan, O. Farokhzad, J. Yeh, R. Langer. “Amplification of Osteogenic Cells from Human Embryonic Stem Cells”, Society for Biomaterials Meeting, Pittsburgh, PA (March, 2006).
  8. J.M. Karp, L.S. Ferreira, A. Khademhosseini, R. Li, N. Choodnovskiy, K. Yan, R. Langer. “Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro”, 52nd Annual Orthopedic Research Society, Chicago, IL (March, 2006).
  9. A. Khademhosseini, G. Eng, J. Yeh, J. Fukuda, J. Blumling III, J.M. Karp, R. Langer, J.A. Burdick. “Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment”, Society for Biomaterials Meeting, Pittsburgh, PA (March, 2006).
  10. A. Khademhosseini. “Academic position search: Perspectives from a recent faculty candidate”, Society for Biomaterials Meeting, Pittsburgh, PA (March, 2006). (Invited speaker)
  11. A. Khademhosseini. “Applications of microscale technologies for Stem Cell Biology”, Cambridge Healthtech Institute’s Commercial Implications of Stem Cell Research: Recognizing the Reality, San Francisco, CA (Feb. 2006).

2005

  1. G. Eng, A. Khademhosseini, J. Yeh, J. Fukuda, J. Blumling, J. Morin-Leisk, J. Gantz, R. Langer, J. Burdick. “Photocrosslinkable hyaluronic acid for surface micropatterning”, 2005 Materials Research Society Fall Meeting, Boston, MA (Nov. 2005).
  2. J. Yeh, A. Khademhosseini, , L. Ferreira, J. Karp, J. Fukuda, G. Eng, J. Blumling, J. Morin-Leisk, J. Gantz, R. Langer, Jason Burdick. “Microstructure mediated patterned co-cultures”, 2005 Materials Research Society Fall Meeting, Boston, MA (Nov. 2005).
  3. J. Fukuda, A. Khademhosseini, J. Yeh, G. Eng, J.J. Cheng, O. Farokhzad, R. Langer. “Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components”, 2005 Materials Research Society Fall Meeting, Boston, MA (Nov. 2005).
  4. A. Khademhosseini, J. Fukuda, G. Eng, J. Yeh, J. Gantz, J. Morin-Leisk, J. Blumling, R. Langer. “Patterned co-cultures of three-dimensional cell spheroids and support cells using microstructure patterned substrates”, 2005 Materials Research Society Fall Meeting, Boston, MA (Nov. 2005).
  5. O. C. Farokhzad, S. Jon, A. Khademhosseini, J.J. Cheng, B. Teply, E. Levy-Nissenbaum, R. Langer. “Cancer nanotechnology: drug encapsulated nanoparticle-aptamer bioconjugates for targeted delivery to prostate cancer cell”. Federation of European Cancer Societies, Paris, France (Oct. 2005).
  6. A. Khademhosseini, O. C. Farokhzad, S. Jon, J.J. Cheng, B. Teply, E. Levy-Nissenbaum, R. Langer. “Micro- and nanoscale technologies for cancer therapy”. 2005 MIT Center for Cancer Research Retreat , Water Valley, NH (Oct. 2005).
  7. J. Cheng, B. Teply, I. Sherifi, E. Levy-Nissenbaum, A. Khademhosseini, R. Langer, O.C. Farokhzad; “Polymeric nanoparticle-aptamer bioconjugates as drug delivery vehicles for targeted prostate cancer therapy", 3rd International Nanomedicine and Drug Delivery Symposium, Baltimore, MD, (Sept. 26-27, 2005)
  8. J. Fukuda, A. Khademhosseini, J. Yeh, G. Eng, R. Langer. “Layer-by-layer deposition of HA and collagen for patterned cell co-cultures” CIMIT Symposium, Boston, MA (Sept. 2005).
  9. S. Yang, J. Fukuda, A. Khademhosseini, J. Burdick, R. Langer. “Fabrication of gradient hydrogels by a microfluidics/photopolymerization process”. CIMIT Symposium, Boston, MA (Sept. 2005).
  10. J.M. Karp, L.S. Ferreira, A. Khademhosseini, A.H. Kwon, J. Yeh, R. Langer. “Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro.” Current Progress in Tissue Engineering”, Cambridge, MA (Sept. 2005).
  11. A. Khademhosseini, G. Eng, J. Yeh, J. Karp, H. Kaji, J. Borenstein, O. Farokhzad, R. Langer. “Fabrication of Multiphenotye cell arrays within reversibly sealed microfluidic channels for high-throughput analysis”, MicroTAS Symp. Proc. In press. Boston, MA (Oct. 2005).
  12. P. Kim, D.–H. Kim, B. Kim, S. K. Choi, S. H. Lee, A. Khademhosseini, R. Langer, K. Y. Suh, “Fabrication of nanostructures of poly(ethylene glycol) and its application to protein and cell patterning” MicroTAS Symp. Proc. In press. Boston, MA (Oct. 2005).
  13. A. Khademhosseini*, J. Fukuda*, G. Eng, J. Yeh, O. Farokhzad, J.J. Cheng, R. Langer. “Layer-by-layer deposition of ionic biomolecules for patterned cellular co-cultures”, Biomedical Engineering Society Meeting, Baltimore, MD (Sept. 2005).
  14. J.M. Karp, L.S. Ferreira, A. Khademhosseini, A.H. Kwon, H. Seong, J. Yeh, R. Langer “Towards the differentiation of human embryonic stem cells for bone tissue engineering” HealthTech’s Institute Stem Cell Research Conference, Cambridge, MA (Aug. 2005).
  15. A. Khademhosseini, J. Yeh, G. Eng, R. Langer. “Controlled embryoid body arrays using micropatterned substrates or non-adhesive microwells”, 2005 International Society of Stem cell Research Meeting, San Francisco, CA (June 2005).
  16. K.Y. Suh, A. Khademhosseini, S.Y. Jon, R. Langer. “Patterning inside microfluidic channels using a soft lithographic method.” The 6th KSME-JSME Thermal and Fluids Engineering Conference, Jeju, KOREA (March 2005).
  17. O. C. Farokhzad, A. Khademhosseini, S. Jon, A. Hermmann, C. Chin, R. Langer. “Development of a Microfluidic Channels for Evaluating Targeted Drug Delivery Vehicles in-vitro”. 2005 International Anesthesia Research Society, Cleveland, OH (2005).
  18. O. C. Farokhzad, S. Jon, A. Khademhosseini, T. Tran, D. LaVan, R. Langer; “Development and Evaluation of Nanoparticle-Aptamer Bioconjugates for Targeted Drug Delivery”. 2005 International Anesthesia Research Society, Cleveland, OH (2005).

2004

  1. A. Khademhosseini, J. Burdick, R. Langer. “Fabrication of gradient hydrogels by a microfluidics/photopolymerization process”. 2004 Materials Research Society Fall Meeting, Boston, MA (Nov. 2004).
  2. A. Khademhosseini, J. Yeh, S.Y. Jon, G. Eng, K.Y. Suh, J. Burdick, R. Langer. “Molded polyethylene glycol microstructures for docking and shear protecting cells within microfluidic channels”. 2004 Materials Research Society Fall Meeting, Boston, MA (Nov. 2004).
  3. K.Y. Suh, A. Khademhosseini, J.M. Yang, G. Eng, D. Berry, T.T. Tran, R. Langer. “Direct Immobilization and Patterning of Hyaluronic Acid on Hydrophilic Substrates”. 2004 Materials Research Society Fall Meeting, Boston, MA (Nov. 2004).
  4. S. Jaffar, K.T. Nam, A. Khademhosseini, R. Langer, A. Belcher. “Layer-by-layer modification and patterned electrostatic deposition of quantum dots” 2004 Materials Research Society Fall Meeting, Boston, MA (Nov. 2004).
  5. A. Khademhosseini, A. Mostasheri, “An overview of socioeconomic characteristics of the Iranian-American community” Iran: Future Prospect, gathering of young Iranian Scholars of North America, Palo Alto, CA (Oct. 2004) *Invited speaker*
  6. A. Khademhosseini, J. Yeh, G. Eng, K.Y. Suh, S.Y. Jon, R. Langer. “Embryonic stem cell self-renewal and differentiation on patterned substrates”, 2004 International Society of Stem cell Research Meeting, Boston, MA (June 2004).
  7. A. Khademhosseini, K.Y. Suh, S.Y. Jon, G. Chen, G. Eng, J. Yeh, R. Langer. “A simple soft lithographic approach to pattern within microfluidic channels: Fabrication of arrays of cells or proteins within microfluidic channels”, 2004 Materials Research Society Spring Meeting, San Francisco, CA (April 2004).
  8. A. Khademhosseini, K.Y. Suh, G. Eng, J. Yeh, J.M. Yang, S. Levenberg, R. Langer. “Controlling stem cell microenvironments using surface patterning and patterned co-cultures”, Keystone symposia, Keystone, CO (March 2004).
  9. J. Yeh, G. Eng, A. Khademhosseini, R. Langer, “Fabrication of multi-phenotype cell arrays within reversibly sealed microfluidic channels for high-throughput analysis”, Harvard-MIT Division of Health Sciences and Technology (HST) Forum, Boston, MA, 2004.
  10. A. Khademhosseini, K.Y. Suh, S. J. Jon, G. Eng, J. Yeh, R. Langer, “Microscale approaches for controlling the cell microenvironment”, Proceedings for Canter for Cancer Research at MIT, Waterville Valley, NH., 2004.
  11. A. Khademhosseini, K.Y. Suh, S. J. Jon, G. Eng, J. Yeh, R. Langer, “Controlling embryoid body formation using micropatterned surfaces”, Proceedings for MIT’s BPEC symposium, 2004.
  12. J. Yeh, G. Eng, A. Khademhosseini, R. Langer, “Controlling stem cell microenvironment using surface patterning and patterned co-cultures”, HST Forum, Boston, MA, 2004.

2003

  1. A. Khademhosseini, S. Jon, K.Y. Suh, G. Eng, J. Yeh, T.T. Tran, R. Langer. “Synthesis and application of a PEG-based copolymer for controlling surface topography and patterning proteins and cells”, NanoTech 2003 Conference, Switzerland. (Nov. 2003).
  2. O. Farokhzad, S. Jon, A. Khademhosseini, T.T. Tran, J. Toy, D. LaVan, R. Langer “Development of PEGylated PLA Nanoparticle-Aptamer Bioconjugates for Targeted Drug Delivery to Prostate Cancer Cells”, 7th annual US-Japan Drug Delivery Conference, Hawaii, USA. (Dec. 2003).
  3. K.Y. Suh, A. Khademhosseini, S.Y. Jon, R. Langer. “Patterned PEG hydrogels for drug delivery”, 7th annual US-Japan Drug Delivery Conference, Hawaii, USA. (Dec. 2003).
  4. K.Y. Suh, J. Seong, A. Khademhosseini, P.E. Laibinis, R. Langer. “Construction of non-biofouling surfaces by polymeric self-assembled monolayer”. 2003 MRS Fall Meeting, Boston, MA (Dec. 2003).
  5. A. Khademhosseini, K.Y. Suh, S. J. Jon, R. Langer, “Controlled microenvironments based on microfluidics and microfabrication for controlling cell-microenvironment interactions”, Proceedings for MIT’s BPEC symposium, 2003.

2001

  1. S. Jon, J. Seong, A. Khademhosseini, T.T. Tran, P.E. Laibinis, R. Langer. “Construction of non-biofouling surfaces by polymeric self-assembled monolayer”. AIChE meeting, San Francisco, CA (Nov. 2003).
  2. A. Khademhosseini, C.Y. Ito, M.V. Sefton, W.L. Stanford, P.W. Zandstra. “In vitro differentiation of bone marrow derived Lin- CD45+ sca-1+ c-kit+ cells into hepatocyte-like cells”, Blood 98 (11):548a (2001).
  3. A. Khademhosseini, W.L. Stanford, M.V. Sefton, P.W. Zandstra. “In vitro differentiation of phenotypically defined bone marrow derived progenitors in liver-like microenvironments”, Annals of Biomedical Engineering. 29 (S1): S-152 (2001).
  4. A. Khademhosseini, W.L. Stanford, M.V. Sefton, P.W. Zandstra. “Endoderm differentiation of murine bone marrow derived cells in vitro”, Proceedings of the 21st Annual Great Lakes Mammalian Development Meeting (April 2001).
  5. J.M. Karp, A. Khademhosseini, et al. "Biomaterials Education from Students’ Perspective", Transactions of the 27th annual Meeting of the Society for Biomaterials (April 2001).
  6. A. Khademhosseini, W.L. Stanford, M.V. Sefton, P.W. Zandstra. “Endoderm differentiation of murine bone marrow derived cells in vitro”, Proceedings of the IBBME Scientific Day. (2001).
  7. A. Khademhosseini, D. Lavan, S. Levenberg, J. Hsiao, A. Kiselyuk, R. Langer, “Generation of controlled microenvironments to study embryonic stem cell differentiation and self-renewal”, Proceedings for MIT’s BPEC symposium, (2002).

2000

  1. M.V. Sefton, A. Khademhosseini, “Engineering Biology: an elective course for first year engineering”, Proceedings of Whitaker Foundation Educational Summit (Dec. 2000).
  2. A. Khademhosseini, M. May, M.V. Sefton "Conformal Coating of Mammalian Cells Immobilized to Polystyrene Beads", Proceedings for Canadian Society Chemical Engineers Conference (Oct. 2000).
  3. A. Khademhosseini, M. May, M.V. Sefton. “A Novel Geometric Configuration for Conformal Coating of Mammalian Cells”, Proceedings of the IBBME Scientific Day (2000).
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