Angela A. Garibaldi Week 3: Difference between revisions
From OpenWetWare
Jump to navigationJump to search
(→10 Biological Terms: add a term) |
(→10 Biological Terms: add 1,2,) |
||
| Line 33: | Line 33: | ||
=== 10 Biological Terms=== | === 10 Biological Terms=== | ||
#'''seroconverting'''- | #'''seroconverting'''- '''serotype'''- The genotype of a unicellular organism as defined by antisera against antigenic determinants expressed on the surface. Therefore; the conversion of the serotype.[http://www.mblab.gla.ac.uk/%7Ejulian/Dict.html Dictionary of Cell and Molecular Biology] | ||
# | #'''non-synonymous mutation- a.k.a. a missense mutation''' -A form of point mutation resulting in a codon that codes for a different amino acid, and thus, causes the synthesis of a protein with an altered amino acid sequence during translation. [http://www.mblab.gla.ac.uk/%7Ejulian/Dict.html Dictionary of Cell and Molecular Biology] | ||
# | # | ||
# | # | ||
Revision as of 21:01, 6 February 2010
Prior knowledge of the HIV virus:
- Currently I don't know very much about the biological aspects of the HIV virus. I only know that it makes the immune system very weak and is a RNA retro virus.
- The following are questions about HIV I would like answered:
- What is the overall molecular mechanism of the disease?
- What type of virus is it specifically and what does this imply?
- What are the mechanisms of some of the methods of treatment currently used?
"Becoming an Expert in Pubmed"
Note: Version of Pubmed used is The following are the searching processes used to find review articles relevant to answering the above questions:
- My first search query was: HIV [TI] evolution Limits:links to free full text, abstracts review, english.
- [TI] specifies that only papers with "HIV" in the title of any papers.
- I've highlighted the PubMed ID number of the article that I chose. This is what is used to complete the bibliography code and used to easily find the paper again.
- The following review seemed most relevant and clear as an introductory paper
- Cohen MS, Hellmann N, Levy JA, DeCock K, and Lange J. The spread, treatment, and prevention of HIV-1: evolution of a global pandemic. J Clin Invest. 2008 Apr;118(4):1244-54. DOI:10.1172/JCI34706 |
Further Articles for Investigation:
- Williams KC and Burdo TH. HIV and SIV infection: the role of cellular restriction and immune responses in viral replication and pathogenesis. APMIS. 2009 May;117(5-6):400-12. DOI:10.1111/j.1600-0463.2009.02450.x |
Markham Article
10 Biological Terms
- seroconverting- serotype- The genotype of a unicellular organism as defined by antisera against antigenic determinants expressed on the surface. Therefore; the conversion of the serotype.Dictionary of Cell and Molecular Biology
- non-synonymous mutation- a.k.a. a missense mutation -A form of point mutation resulting in a codon that codes for a different amino acid, and thus, causes the synthesis of a protein with an altered amino acid sequence during translation. Dictionary of Cell and Molecular Biology
