Augusto & Jessica's Research Proposal Information: Difference between revisions
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We want to engineer a microorganism or virus that will improve either: | We want to engineer a microorganism or virus that will improve either: | ||
*sewage water treatment/waste degradation | *sewage water treatment/waste degradation (probably this) | ||
*biofuel synthesis | *biofuel synthesis | ||
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==Social Context== | ==Social Context== | ||
*under-treated sewage is the main source of pathogens in water | *under-treated sewage is the main source of pathogens in water | ||
==Random Thoughts== | |||
*If we design a bacteria, perhaps utilize a protein degradation switch that will allow the bacteria to be destroyed at will | |||
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Grilly C, Stricker J, Pang WL, Bennett MR, Hasty J. A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae . Molecular Systems Biology 2007; 3:127 | Grilly C, Stricker J, Pang WL, Bennett MR, Hasty J. A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae . Molecular Systems Biology 2007; 3:127 | ||
Revision as of 12:30, 15 November 2007
We want to engineer a microorganism or virus that will improve either:
- sewage water treatment/waste degradation (probably this)
- biofuel synthesis
Sewage Water Treatment
Scientific Background
- Bacteria are commonly used indicators of the effectiveness of wastewater treatment
- May not accurately indicate the effectiveness of removing viruses and protozoa
- Bacteriophages have been proposed to be potential indicators of viruses
- sulphite-reducing bacteria have been proposed to be potential indicators of viruses
Social Context
- under-treated sewage is the main source of pathogens in water
Random Thoughts
- If we design a bacteria, perhaps utilize a protein degradation switch that will allow the bacteria to be destroyed at will
References
Gaussier H, Yang Q et al. Building a virus from scratch: assembly of an infectious virus using purified components in a rigorously defined biochemical assay system. Journal of Molecular Biology 2004; 357:1154-66
Kim DY and Rhe YH. Biodegradation of microbial and synthetic polyesters by fungi. Applications of Microbiology Biotechnology 61:300-308
Lucena F, Duran AE, et al. Reduction of bacterial indicators and bacteriophages infecting faecal bacteria in primary and secondary wastewater treatments. Journal of Applied Microbiology 2004; 97:1069-1076
Grilly C, Stricker J, Pang WL, Bennett MR, Hasty J. A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae . Molecular Systems Biology 2007; 3:127
