BIOL398-01/S10:HIV Structure

Background

• NCBI Structure Database
• Cn3D software site

References

1. Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, and Hendrickson WA. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature. 1998 Jun 18;393(6686):648-59. DOI:10.1038/31405 |

   Kwong et al. (1998) link to full text

2. Stanfield R, Cabezas E, Satterthwait A, Stura E, Profy A, and Wilson I. Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. Structure. 1999 Feb 15;7(2):131-42. DOI:10.1016/s0969-2126(99)80020-3 |

   Stanfield et al. (1999) link to full text

3. Stanfield RL, Ghiara JB, Ollmann Saphire E, Profy AT, and Wilson IA. Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop. Virology. 2003 Oct 10;315(1):159-73. DOI:10.1016/s0042-6822(03)00525-7 |

   Stanfield et al. (2003) link to full text

Week 7

Week 8

• Journal Club presentations in class.

Week 9

• Project work session

Week 10

• Project presentations in class.