BIOL398-01/S11:Week 9: Difference between revisions

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# Make a list of at least 10 biological terms for which you did not know the definitions when you first read the article.  Define each of the terms.  You can use the glossary in any molecular biology, cell biology, or genetics text book as a source for definitions, or you can use one of many available online biological dictionaries (links below).  List the citation(s) for the dictionary(s) you use, providing a URL to the page is fine.
# Make a list of at least 10 biological terms for which you did not know the definitions when you first read the article.  Define each of the terms.  You can use the glossary in any molecular biology, cell biology, or genetics text book as a source for definitions, or you can use one of many available online biological dictionaries (links below).  List the citation(s) for the dictionary(s) you use, providing a URL to the page is fine.
# Write an outline of the article.  The length should be the equivalent of 2 pages of standard 8 1/2 by 11 inch paper (you can check this by clicking on "Print preview" in your browser).  Your outline can be in any form you choose, but you should utilize the wiki syntax of headers and either numbered or bulleted lists to create it.  The text of the outline does not have to be complete sentences, but it should answer the questions listed below and have enough information so that others can follow it.  However, your outline should be in YOUR OWN WORDS, not copied straight from the article.
# Write an outline of the article.  The length should be the equivalent of 2 pages of standard 8 1/2 by 11 inch paper (you can check this by clicking on "Print preview" in your browser).  Your outline can be in any form you choose, but you should utilize the wiki syntax of headers and either numbered or bulleted lists to create it.  The text of the outline does not have to be complete sentences, but it should answer the questions listed below and have enough information so that others can follow it.  However, your outline should be in YOUR OWN WORDS, not copied straight from the article.
#*What is the main result presented in this paper?
#* What is the main result presented in this paper?
#*What is the importance or significance of this work?
#* What is the importance or significance of this work?
#*What were the limitations in previous studies that led them to perform this work?
#* How did they treat the cells (what experiment were they doing?)
#*What were the methods used in the study?
#* What strain(s) of yeast did they use?  Was the strain haploid or diploid?
#*Briefly state the result shown in each of the figures.
#* What media did they grow them in?  What temperature?  What type of incubator?  For how long?
#** What do the X and Y axes represent?
#* What controls did they use?
#** How were the measurements made?
#* How many replicates did they perform per treatment or timepoint?
#** What trends are shown by the plots and what conclusions can you draw from the data?
#* What method did they use to prepare the RNA, label it and hybridize it to the microarray?
#* What is the overall conclusion of the study and what are some future directions for research?
#* What mathematical/statistical method did they use to analyze the data?
#* What transcription factors did they talk about?
#* Briefly state the result shown in each of the figures and tables.
# Each group of students will be assigned one section of the paper.  The group will be responsible for explaining the section, including any tables/figures in detail to the class.  Groups will be assigned on 3/10/11 in class.   
# Each group of students will be assigned one section of the paper.  The group will be responsible for explaining the section, including any tables/figures in detail to the class.  Groups will be assigned on 3/10/11 in class.   



Revision as of 11:55, 9 March 2011

BIOL398-01: Biomathematical Modeling

MATH 388-01: Survey of Biomathematics

Loyola Marymount University

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This journal entry is due on Thursday, March 24 at midnight PST (Wednesday night/Thursday morning). NOTE new due date and that the server records the time as Eastern Standard Time (EST). Therefore, midnight will register as 03:00.

Individual Journal Assignment

  • Store this journal entry as "username Week 9" (i.e., this is the text to place between the square brackets when you link to this page).
  • Create the following set of links. (HINT: you can do all of this easily by adding them to your template and then using the template on your pages.)
    • Link to your journal entry from your user page.
    • Link back from your journal entry to your user page.
    • Link to this assignment from your journal entry.
    • Don't forget to add the "BIOL398-01/S11" category to the end of your wiki page.

Read

Preparation for Journal Club 2

  1. Make a list of at least 10 biological terms for which you did not know the definitions when you first read the article. Define each of the terms. You can use the glossary in any molecular biology, cell biology, or genetics text book as a source for definitions, or you can use one of many available online biological dictionaries (links below). List the citation(s) for the dictionary(s) you use, providing a URL to the page is fine.
  2. Write an outline of the article. The length should be the equivalent of 2 pages of standard 8 1/2 by 11 inch paper (you can check this by clicking on "Print preview" in your browser). Your outline can be in any form you choose, but you should utilize the wiki syntax of headers and either numbered or bulleted lists to create it. The text of the outline does not have to be complete sentences, but it should answer the questions listed below and have enough information so that others can follow it. However, your outline should be in YOUR OWN WORDS, not copied straight from the article.
    • What is the main result presented in this paper?
    • What is the importance or significance of this work?
    • How did they treat the cells (what experiment were they doing?)
    • What strain(s) of yeast did they use? Was the strain haploid or diploid?
    • What media did they grow them in? What temperature? What type of incubator? For how long?
    • What controls did they use?
    • How many replicates did they perform per treatment or timepoint?
    • What method did they use to prepare the RNA, label it and hybridize it to the microarray?
    • What mathematical/statistical method did they use to analyze the data?
    • What transcription factors did they talk about?
    • Briefly state the result shown in each of the figures and tables.
  3. Each group of students will be assigned one section of the paper. The group will be responsible for explaining the section, including any tables/figures in detail to the class. Groups will be assigned on 3/10/11 in class.

Online Biological Dictionaries

Shared Journal Assignment

  • Store your journal entry in the shared Class Journal Week 9 page. If this page does not exist yet, go ahead and create it (congratulations on getting in first :) )
  • Link to your journal entry from your user page.
  • Link back from the journal entry to your user page.
  • Sign your portion of the journal with the standard wiki signature shortcut (~~~~).
  • Add the "BIOL398-01/S11" category to the end of the wiki page (if someone has not already done so).

Reflection