BISC 219/F10:Assignments

From OpenWetWare

Revision as of 08:59, 16 August 2010 by Tucker Crum (Talk | contribs)
Jump to: navigation, search
Wellesley College BISC 219 Genetics

Graded Assignments

Lab Assigned Lab Due Assignment
description
Point Value
(Total 200)
Lab 1 Lab 2 Complete entry survey (2.5pts); Submit preliminary cross results Day 3 (1 pt);
Summarize experimental question, design; Diagram crosses; Explain data interpretation (9 pts) BISC_219/F10: Assignment_1_Lab1
12.5
Lab 2 Lab 3 Statement of Series 2 experimental question & goals. Outline of experimental process including : Mutant Hunt, Linkage Analysis, Mapping the Mutation to a chromosome and to a particular location, Complementation Analysis, Determining whether or not the mutation has been previously characterized, & Defining the gene sequence and protein change through DNA sequence analysis. 1-2 page summary of how you will determine the exact location of the gene and the sequence change likely to be associated with a phenotypic anomally.BISC_219/F10: Assignment_Series2_Outline_Summary 10
Lab 2 Lab 4
Results Section
BISC 219/F10: Assignment Help- Data Analysis 1
Autosomal vs. Sex linked inheritance
30
Lab 3 Lab 4 Diagram the expected results (genotype and phenotype)for the crosses and self-fertilization progeny in the Linkage Testing work that you will do over the next several weeks. Highlight the progeny that will be used to continue each step of the process. Include a narrative description of the rational for the crosses and summarize the interpretation of the results that will allow determination of the linkage group to which your mutated gene of interest belongs. Assignment information and rubric found at BISC_219/F10: Assignment_Series2_Linkage Testing Crosses 5
Lab 4 Lab 5 Diagram the expected results (genotype and phenotype)for the crosses and self-fertilization progeny in the Mapping work that you will do over the next several weeks. Make sure you highlight the progeny that will be used to continue each step of the process. 5
Lab 5 Lab 6 Explain complementation analysis in general and then explain specifically how you will use it to confirm and expand your linkage and mapping work. Wikipedia has a good general introduction at 5
Lab 6 Lab 7 Analyze your mutant gene's DNA sequence and write a 1-2 page summary describing briefly and generally how chain-termination sequencing is accomplished and then specifically describe the mutation most likely to be responsible for your phenotype change by comparing the wild type sequence to the mutant's gene. Include the resulting protein or regulatory product change and its likely significance in the worm and, if possible, in other species. 10
Lab 6 Week of Nov. 1 Scientific Research Report on Series2 work Classical (Forward) Genetics. Assignment information found at BISC 219/F10: Assignment_ Series2_Classical Genetics Paper
50
Lab 7 Lab 8 Convert all the lab protocols performed so far for Series 3: Reverse Genetics Using RNAi to M&M. Assignment information found at: BISC_219/F10: Assignment_Series3_ Materials and Methods 15
Lab 8 Lab 9
Lab 9 Lab 10
Lab 10 Lab 11
Lab 11 Lab 12 Full scientific research report due Fri. Dec 10 at 4pm for all students. Assignment information found at BISC_219/F10: Assignment_Series3_Reverse Genetics Paper using RNAi 50
Other Exit Survey
participation
2.5


Assignments

Lab 1 Assignment: BISC_219/F10: Assignment_1_Lab1
Lab 2 Assignment: BISC_219/F10: Assignment_Series2_Outline_Summary
Lab 2-3 Assignment: BISC 219/F10: Assignment Help- Data Analysis 1 Autosomal vs. Sex linked inheritance
Lab 3 Assignment: BISC_219/F10: Assignment_Series2_Linkage Testing Crosses
Lab 4 Assignment: BISC_219/F10: Assignment_Series2_Mapping Crosses
Lab 5 Assignment: BISC_219/F10: Assignment_Series2_Complementation
Lab 6 Assignment: BISC_219/F10: Assignment_Series2_DNA Sequencing
Lab 6 Assignment: BISC 219/F10: Assignment_ Series2_Classical Genetics Paper Scientific Paper on Forward Genetics Project
Lab 8 Assignment: BISC_219/F10: Assignment_Series3_ Materials and Methods Convert all the lab protocols performed for Series 3 so far into Materials & Methods

Lab 11 Assignment: BISC_219/F10: Assignment_Series3_Reverse Genetics Paper using RNAi Full Scientific Paper on Reverse Genetics Project using RNAi
Personal tools