BME100 f2014:Group17 L2: Difference between revisions

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'''Experiment 2'''<br>
'''Experiment 2'''<br>


[[Image:BME_Lab_2_rat_study_Group17.jpg‎|200px|Description of image]]<br><br>
[[Image:BME_Lab_2_rat_study_Group17.jpg‎|Description of image]]<br><br>


==Results==
==Results==
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'''Experiment 1''' <br>
'''Experiment 1''' <br>
Two experiments were conducted in this study on the relationship between inflammotin levels and medication dosage, one on rats, and one on humans.  Unlike the human experiment, the rat experiment only looked at two groups, two different dosage levels, t-test analysis was used to analyze possible relationships
Two experiments were conducted in this study on the relationship between Inflammotin levels and medication dosage, one on rats, and one on humans.  Unlike the human experiment, the rat experiment only looked at two groups, two different dosage levels. These included a control group of 0 mg and one of 10 mg. T-test analysis was used to analyze possible relationships. The p value was determined to be 0.867403, which is greater than 0.05, indicating a lack of relationship.
 
 
[[Image:ratdatatval.jpg‎|200px|T-Test analysis from Experiment 1]]






'''Experiment 2''' <br>
'''Experiment 2''' <br>
The human study used ANOVA test analysis, as it looked at more than two groups, 0mg,5 mg, 10mg, and 15 mg dosages were studied.  
The human study used ANOVA test analysis, as it looked at more than two groups. Dosages of 0mg, 5 mg, 10mg, and 15 mg were studied. Through ANOVA, the p value was determined to be 1.4X10^-16, which like in the rat study, was less than 0.05, and has certain implications.


'''Conclusion from Tests''' <br>From the P-Value of the first experiment, it can be determined that the test involving rats followed the null hypothesis of increased protein levels from LSP dosages. The first experiment experienced positive results most likely because of the low variety and only two different dosages. The second experiment on the other hand has more variety of dosages and has more results. The P-value for the second test was found to be lesser than 0.05 which results in rejecting the null hypothesis.


[[Image:LBAnova.jpg‎|200px|T-Test analysis from Experiment 1]]
<br><br>
<br><br>


==Summary/Discussion==
==Summary/Discussion==
In both the rat and human experiments, results showed that the agent does in fact raise protein levels. The experiment with the rats was not as accurate due the small amount of tests taken. The higher standard deviation found in the 10mg rat group,7.4 as opposed to 2.2 in the control group, also indicates a problem with the study. It also showed a very small amount of increase as opposed to the increase that the human study showed. The standard deviation is lower for doses of 0 mg and 5 mg in humans than shown in the rats. Once the dosage increased, the tables were turned and it became higher in humans. The same pattern was found when looking at standard error. With the rat study only two different dosages were tested unlike the human study, which was tested at 0, 5, 10, and 15 mg. While it is proven that Inflammotin increased protein levels in both experiments, accuracy would be higher if more tests were to be run on rats at different dosages.

Latest revision as of 22:43, 16 September 2014

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LAB 2 WRITE-UP

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Experiment 1

Experiment 2

Description of image

Results

Experiment 1

Description of image

Experiment 2

Description of image




Analysis

Experiment 1
Two experiments were conducted in this study on the relationship between Inflammotin levels and medication dosage, one on rats, and one on humans. Unlike the human experiment, the rat experiment only looked at two groups, two different dosage levels. These included a control group of 0 mg and one of 10 mg. T-test analysis was used to analyze possible relationships. The p value was determined to be 0.867403, which is greater than 0.05, indicating a lack of relationship.


T-Test analysis from Experiment 1


Experiment 2
The human study used ANOVA test analysis, as it looked at more than two groups. Dosages of 0mg, 5 mg, 10mg, and 15 mg were studied. Through ANOVA, the p value was determined to be 1.4X10^-16, which like in the rat study, was less than 0.05, and has certain implications.

Conclusion from Tests
From the P-Value of the first experiment, it can be determined that the test involving rats followed the null hypothesis of increased protein levels from LSP dosages. The first experiment experienced positive results most likely because of the low variety and only two different dosages. The second experiment on the other hand has more variety of dosages and has more results. The P-value for the second test was found to be lesser than 0.05 which results in rejecting the null hypothesis.

T-Test analysis from Experiment 1



Summary/Discussion

In both the rat and human experiments, results showed that the agent does in fact raise protein levels. The experiment with the rats was not as accurate due the small amount of tests taken. The higher standard deviation found in the 10mg rat group,7.4 as opposed to 2.2 in the control group, also indicates a problem with the study. It also showed a very small amount of increase as opposed to the increase that the human study showed. The standard deviation is lower for doses of 0 mg and 5 mg in humans than shown in the rats. Once the dosage increased, the tables were turned and it became higher in humans. The same pattern was found when looking at standard error. With the rat study only two different dosages were tested unlike the human study, which was tested at 0, 5, 10, and 15 mg. While it is proven that Inflammotin increased protein levels in both experiments, accuracy would be higher if more tests were to be run on rats at different dosages.