BME100 f2015:Group9 1030amL6

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BME 100 Fall 2015 Home
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Lab Write-Up 1 | Lab Write-Up 2 | Lab Write-Up 3
Lab Write-Up 4 | Lab Write-Up 5 | Lab Write-Up 6
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OUR COMPANY

Name: Glenna Bea Embrador
Name: Ian Quinn
Name:Eric M Rhoades
Name: Chase Gregor
Name: Broderick T. Laese
Name: Nimisha Tanna


LAB 6 WRITE-UP

Bayesian Statistics

Overview of the Original Diagnosis System


Calculation 1

Variable Description Numerical Value
A Positive final test conclusion 0.41
B Positive PCR reaction 0.45
P(B|A) Probability of a Positive PCR reaction given that the patient receives a positive final test conclusion 0.85
P(A|B) Probability of a positive final test conclusion given a positive PCR reaction 0.77

Calculation 2

Variable Description Numerical Value
A Negative final test conclusion 0.53
B Negative Diagnostic Signal 0.49
P(B|A) Probability of a negative diagnostic signal given that the patient receives a negative final test conclusion 0.82
P(A|B) Probability of a negative final test conclusion given that the patient receives a negative diagnostic signal 0.89

Calculation 3

Variable Description Numerical Value
A Patient will develop disease 0.31
B Positive final test conclusion 0.41
P(B|A) Probability that there will be a positive final text conclusion given that the patient develops the disease 0.4
P(A|B) Probability that the patient develops the disease given that there is a positive final test conclusion 0.3

Calculation 4

Variable Description Numerical Value
A Patient will not develop the disease 0.6875
B Negative final test conclusion 0.53
P(B|A) Probability that there will be a negative final text conclusion given that the patient does not develop the disease 0.54
P(A|B) Probability that the patient does not develop the disease given that there is a negative final test conclusion 0.38

What Bayes Statistics Imply about This Diagnostic Approach



9. Which Open PCR parts does each of the 3-D files represent? Each 3-D files represent the following: Back, Bottom, Front, Side, Sides with ports, and Top

Intro to Computer-Aided Design

TinkerCAD

Using TinkerCad was relatively simple after following the step by step tutorials that showcase all the tools possible. TinkerCad is user-friendly and despite being simple, had a variety of options in order to create different things. The first thing we did was follow the tutorial in order to understand the different tools such as zooming, the shapes, and grouping shapes together. After the tutorial, we downloaded Dr. Haynes files in order to begin redesigning the fluorimeter. Dr. Haynes files were much better suited for this particular lab compared to the basic tools given, however, when we were redesigning the fluorimeter so that the camera phone can take better images for data, the other shapes became useful. During the Computer-Aided Design we tried out different options and settled on creating a very mobile attachment to the fluorimeter so that the phone can get the best angle of the data. We used several shapes in order to complete the finished product. It was a bit difficult at first because if the shape is too big, it was hard viewing the whole device when the screen only showed so much.


Our Design



Our design keeps the basic box-shape of the fluorimeter, however, we have added an attachment (colorful portion) that makes taking down data much easier. The slider, which is in pastel pink, slides in and out of the fluorimeter in order to get as close as needed to the data that is being collected. The purpose of the sliding mechanism is to prevent the user from taking the phone out of the cradle constantly, and enable more mobile movement without disrupting anything. The light blue circles enable rotating ability of the attachment for more movement as well, and similar to a "selfie stick" the blue rod extends when needed in order to optimize the best viewing option. Finally, the light purple portion is where the phone is, and the difference from the OpenPCR design and this is that this design works like a clamp in order to secure the phone steady. On the other hand, in the OpenPCR lab, the cradle was unstable and the phone constantly fell or changed direction with slight movement which is why we opted for a design where we are able to position the phone and keep it at that position without it being moved.

Feature 1: Consumables

Consumables​: plastics, pipettor, and reagents (PCR mix, primers) The OpenPCR​machine and software The Fluorimeter system​(including slides, stand, etc.)Numerical Value
STRENGTH: Cheap, durable, and already prepared respectively STRENGTH: Simple and easy to use. STRENGTH: Plenty of room to work with, besides the box preventing light exposure.
WEAKNESS: They could be easily misplaced without proper labeling. STRENGTH: Simple and easy to use. WEAKNESS: A more stable stand for phone/camera should be considered.

Feature 2: Hardware - PCR Machine & Fluorimeter

From Dee's Nuts n Bolts, The company that brought you the tectonic sole! The D and magnet