BME100 s2015:Group12 12pmL6: Difference between revisions

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<!-- Instruction 1: In your own words, discuss what the results for calculations 1 and 2 imply about the reliability of the individual PCR replicates for concluding that a person has the disease SNP or not. Please do NOT type the actual numerical values here. Just refer to the Bayes values as being "close to 1.00 (100%)" or "very small." Discuss at least three possible sources of human or machine/device error that could have occurred during the PCR & detection steps that could have affected the Bayes values in a negative way. -->
<!-- Instruction 1: In your own words, discuss what the results for calculations 1 and 2 imply about the reliability of the individual PCR replicates for concluding that a person has the disease SNP or not. Please do NOT type the actual numerical values here. Just refer to the Bayes values as being "close to 1.00 (100%)" or "very small." Discuss at least three possible sources of human or machine/device error that could have occurred during the PCR & detection steps that could have affected the Bayes values in a negative way. -->


<!-- Instruction 1: In your own words, discuss what the results for calculations 3 and 4 imply about the reliability of PCR for *predicting the development disease* (referred to as "diagnosis"). Please do NOT type the actual numerical values here. Just refer to the Bayes values as being "close to 1.00 (100%)" or "very small."  -->
<!-- Instruction 1: In your own words, discuss what the results for calculations 3 and 4 imply about the reliability of PCR for *predicting the development disease* (referred to as "diagnosis"). Please do NOT type the actual numerical values here. Just refer to the Bayes values as being "close to 1.00 (100%)" or "very small."  -->

Revision as of 21:16, 18 April 2015

BME 100 Spring 2015 Home
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Lab Write-Up 1 | Lab Write-Up 2 | Lab Write-Up 3
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OUR COMPANY

Name: Corey Soto
Name: Kyla Richardson
Name: Waseem Aljaid
Name: Syeda Rizvi
Name: William Chmielewski


LAB 6 WRITE-UP

Bayesian Statistics

Overview of the Original Diagnosis System

An assembly of 34 teams, each composing of around 5 to 6 research team members, were created. Each team was given two patients for data analysis, totaling 68 patients. The use of PCR allowed the amplification of DNA, ensuring that the research conducted was able to use the proper amounts of DNA needed. During the study, each sample collected from the patient was analyzed for SNP, or single nucleotide polymorphism. This was to determine whether each sample was suspectible to disease or if there was a lack of an affliction.

The use of the Bayesian equation was critical in providing the conclusions made from the study. It was apparent that some of the teams were unable to secure the data needed for analysis. Due to the high probability of data inaccuracy, the Bayesian method provided assistance in increasing credibility and reducing ambiguity. One suggestion may be that the technical method of collecting the study's data (the fluorimeter setup, the ImageJ calibration, etc.) may have played a key role in the inconsistencies found during the research. Providing a more stable method of data analysis would be strongly recommended for future studies.


What Bayes Statistics Imply about This Diagnostic Approach



Computer-Aided Design

TinkerCAD


Our Design





Feature 1: Consumables Kit

Feature 2: Hardware - PCR Machine & Fluorimeter