BME100 s2017:Group5 W1030AM L1

BME 100 Spring 2017	Home People Lab Write-Up 1 | Lab Write-Up 2 | Lab Write-Up 3 Lab Write-Up 4 | Lab Write-Up 5 | Lab Write-Up 6 Course Logistics For Instructors Photos Wiki Editing Help
OUR TEAM Esther Sim Marci Bandala Emina Causevic Neil Collins Cooper Bertke Chase Frailey LAB 1 WRITE-UP Health Care Issue We will be developing an ear clip sensor/transmitter that continually monitors glucose levels. Our device will be a small, wireless ear clip sensor that will fit on one’s earlobe and transmit one’s glucose levels to a smartphone app that individuals can consistently monitor. Our device will be able to give consistent, accurate glucose readings for patients with type 1 and type 2 diabetes, and will be able to help individuals prevent complications related to diabetes. Our device will be non-invasive, battery-operated, and will be able to replace the continuous glucose monitors (CGM) that are inserted into the skin. Customer Validation Patients - Diabetics, Hypoglycemics, Hyperglycemics; - A group of these patients could be interviewed through the locations found through the providers. Physicians - Endocrinologists, Nurse educators; - A group of these professionals could be interviewed through the locations found through the providers. Providers - Hospitals (Example: Saint Joseph’s Hospital and Medical Center Address: 350 W Thomas Rd, Phoenix, AZ 85013 Phone:(602) 406-3000) - Clinics (Example: Cleveland Clinic's Diabetes Center 10685 Carnegie, Cleveland, OH 44106. Number: 216.444.6568) Purchasers - Diabetes Research Institute; 200 S. Park Road, Suite 100 Hollywood, FL 33021 Phone: (954) 964-4040 Toll-free (800) 321-3437 Fax: (954) 964-7036 E-mail: info@drif.org - ADA (American Diabetes Association); Address: 5333 N 7th St # B212, Phoenix, AZ 85014 Phone:(602) 861-4731 - Roche Diabetes Care, Inc.; Address: 8900 Hague Rd, Indianapolis, IN 46256 Phone:(317) 521-2000 - Medtronic; Phone: (800)633-8766 - Aptus Endosystems; Address: 271 Gibraltar Dr, Sunnyvale, CA 94089 Phone:(408) 530-9050 - Abbott; Toll-free number: (800) 227-5767 - GE Healthcare; Number: (866) 281-7545. - Insulet; Address: 600 Technology Park Dr #200, Billerica, MA 01821 Phone:(978) 600-7000 - Tandem Diabetics; Address: 11045 Roselle St, San Diego, CA 92121 Phone:(858) 366-6900 - Mannkind Incorporated; 25134 Rye Canyon Loop Suite 300 Valencia, CA 91355 (661) 775-5300 - Dexcom; Address: 6340 Sequence Dr, San Diego, CA 92121 Phone:(858) 200-0200 - LifeScan (Part of Johnson and Johnson); Phone: 1-800-227-8862 - JDRF Diabetes Research Foundation; 800-533-2873 info@jdrf.org 26 Broadway, 14th floor New York, NY 10004 - World Diabetes Foundation; Address: Brogårdsvej 70, 2820 Gentofte, Denmark Phone:+45 44 42 25 56 - Children’s Diabetes Foundation; Address: 4380 S Syracuse St #430, Denver, CO 80237 Phone:(303) 863-1200 Payers - Health Insurance (Medicare, Medicaid, etc…); Example: Phoenix Co Inc Address: Phoenix Plaza, Phoenix Insurance Company,, 1 American Row, Hartford, CT 06103 Phone:(800) 628-1936 Competitors IP Position In 2003, a patent was filed by Larry W. Ishler for a non-invasive blood glucose monitoring system that used small sensors on multiple parts of the ear. The device worked by calibrating itself to the body’s natural heat within .035 Centigrade, and the calculation found was that for each 1 mg/dl that the blood glucose increases, body temperature would rise by .024 Centigrade, and vice versa. It has garnered little to no support as few groups wish to invest in new non-invasive technologies due to failures in the past, which is outlined here: (http://www.healthline.com/diabetesmine/the-non-invasive-glucose-monitor-no-one-wanted#3) Link to the patent: (https://www.google.com/patents/US6949070?dq=ear+glucose+monitor&hl=en&sa=X&ved=0ahUKEwiTiqf6893RAhVX7WMKHWjSClMQ6AEIGjAA) Many different patents have been filed to monitor blood glucose through the ear, but few of them have garnered any funding or support. Within those patents, such concepts as an ear canal implant or probes that measure acoustic velocity signals within the ear are found. As stated before, these projects have found no grounding as continuous blood glucose monitoring systems. In the case of non-ear based continuous blood glucose monitoring systems, there are a few patents placed on implants that constantly measure blood glucose levels. However, these implants are oftentimes painful and have to be replaced continuously. One such patent was found, filed by a Chinese inventor, as can be seen here. (https://www.google.com/patents/CN101548892B?cl=en&dq=continuous+glucose+monitor+implant&hl=en&sa=X&ved=0ahUKEwjYvvmh-t3RAhUqj1QKHeq7D7QQ6AEIGjAA) This patent naturally does not claim that the device is painful to implement, but many peer evaluations found around the internet attest to the painfulness and tediousness of the implants. In particular, microsensors placed under the skin once every few days were mentioned in numerous places, but we were unable to locate the specific patent through Google Patents. In summary, there are many different patents filed in the various areas of blood glucose monitoring, including the domains of ear measurements and continuous measurement that we are attempting to work with. Outside of the the ear-based and continuous methods, hundreds of other methods of glucose monitoring patents are present, meaning that the IP position is likely between a 2 or a 3. Fundability Worksheet Scores Competitors 2 At this time, continuous glucose monitoring exists, but as it is cumbersome and invasive, new methods are still being sought. Customer Validation 1 As we have not had the time and resources to actually estimate customer interest, this score is an estimate. IP Position 3 Many different patents exist for our same venture, and many glucose monitoring patents are present meaning it is easy to patent, but that means many exist already.