BME494 Project Group9: Difference between revisions
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•The meter is practical because the blood sample is relatively small and can be extracted at any time. Normal tests for Vitamin D deficiency require | •The meter is practical because the blood sample is relatively small and can be extracted at any time. Normal tests for Vitamin D deficiency require laboratory procedures and time. | ||
•The meter will be user friendly and structured similarly to our current | |||
•The meter will be user friendly and structured similarly to our current glucose meters. | |||
•Normal Levels of Vitamin D may slightly vary with each individual; the meter is not more than a medical tool to indicate deficiency, and it cannot replace a doctor. | •Normal Levels of Vitamin D may slightly vary with each individual; the meter is not more than a medical tool to indicate deficiency, and it cannot replace a doctor. | ||
•This meter will be targetting children and elders in particular because thos age groups are most prone to deficiency. For kids, pricking fingers for small bloods samples won't be ideal if it's a routine | •This meter will be targetting children and elders in particular because thos age groups are most prone to deficiency. For kids, pricking fingers for small bloods samples won't be ideal if it's a routine | ||
Revision as of 23:53, 14 March 2012
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ABSTRACT
BACKGROUND
The proposed design has the potential to be used as a simple and efficient diagnostic test.
PROOF OF CONCEPT DESIGNIn the presence of 25(OH)D3 in blood, the co-transcription factor and promoter for the CYP21B1 are activated. When the promoter is activated, it expresses the enzyme that causes a chemical change to to the active form of Vitamin D. This active form, 1-25-DiHydroxyVitamin D3, is created in the kidney. If the promoter is activated, then it will express the enzyme that chemically changes to the active form of vitamin D in the kidney.
FUTURE VISION: D-Vitameter: Ideally this would be a device that would benefit from the proposed technology. This compact and portable device would allow patients to get a reading of their ability to produce Vitamin D by just using one drop of blood. The basic components of this small device would be an enclosed box with a small polycarbonate window. The device will allow to introduce a sample in a microscope slide and shine a UV light to detect presence of 25(OH).
TESTING
When 25(OH)D3 is present, ideally there would be a 100% GFP concentration
HUMAN PRACTICES•The meter is practical because the blood sample is relatively small and can be extracted at any time. Normal tests for Vitamin D deficiency require laboratory procedures and time.
OUR TEAM
Biomedical Engineering, SBHSE, I am interested in learning the general concepts of synthetic biology and its applications, I will be graduating this semester! http://openwetware.org/wiki/User:Carolina_Tostado
Your area of study/ academic program/ major, why you are taking BME494, and something interesting about yourself. You may add a link to your personal OWW page.
Your area of study/ academic program/ major, why you are taking BME494, and something interesting about yourself. You may add a link to your personal OWW page.
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