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==What We Do==


[[Image:Barnes_homediagram.png]]
[[Image:Barnes_homediagram.png]]


We apply mathematical modelling, experimental methods and Bayesian statistics to problems in systems and synthetic biology. Our goal is to make biology more predictive.
The research in the Barnes group focuses on using synthetic biology and computational methods across a range of areas. In general, we aim to make biology more 'engineerable', predictable and robust. Some of the projects which we have studied are listed below.


We build models of biological systems expressed as dynamical systems (differential equations, stochastic processes) in order to better understand them, elucidate their regulatory mechanisms and enable us to engineer them for therapeutic purposes. We use techniques from molecular biology, fluorescent time course microscopy and flow cytometry to test model predictions and to help us better understand the underlying biology so that we can create more accurate representations.
==Projects==
* Computational approaches for controlling mixed microbial communities
* Computation using patterning of bacterial colonies
* Engineering the microbiome for therapeutic and diagnostic applications
* Construction of therapeutically relevant bacterial biosensors
* Computational design and characterisation of synthetic gene networks


==Who We Are and What We Do==
==Who We Are==
*[[Barnes:Lab Members|Lab Members]]
*[[Barnes:Lab Members|Lab Members]]
*[[Barnes:Research|Research]]
*[http://www.cssb.cs.ucl.ac.uk/barnes_group Computational Systems and Synthetic Biology group]
*[[Barnes:Publications|Publications]]
<-- *[[Barnes:Talks|Talks]] -->


==General Information==
==Useful Links==
* [http://www.cssb.cs.ucl.ac.uk/ Computational Systems and Synthetic Biology group]
* [http://www.ucl.ac.uk/cdb UCL Department of Cell and Developmental Biology]
* [http://www.ucl.ac.uk/cdb UCL Department of Cell and Developmental Biology]
* [http://www.ucl.ac.uk/ University College London (UCL)]
* [http://www.ucl.ac.uk/ University College London (UCL)]


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Latest revision as of 07:47, 29 June 2018

UCL Computational Systems and Synthetic Biology


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What We Do

The research in the Barnes group focuses on using synthetic biology and computational methods across a range of areas. In general, we aim to make biology more 'engineerable', predictable and robust. Some of the projects which we have studied are listed below.

Projects

  • Computational approaches for controlling mixed microbial communities
  • Computation using patterning of bacterial colonies
  • Engineering the microbiome for therapeutic and diagnostic applications
  • Construction of therapeutically relevant bacterial biosensors
  • Computational design and characterisation of synthetic gene networks

Who We Are

Useful Links