Barry Canton/Mitochondria
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Nucleic acid import into mitochondria in vivo
DNA
- Author - method - mitochondria type
- Souza et al. - DQAsomes, DNA-MLS conjugate - in vivo mammalian mitochondria
- DQAsomes release DNA near to mitochondria.
- MLS is conjugated to the dsDNA via a commercial "genegrip".
- Doesn't work if you use a liposome rather than a DQAsome.
- Khan et al. - PTD-MLS-TFAM-DNA conjugate - in vivo mammalian mitochondria
- Similar idea to Souza et al. but they use a PTD to get it into the cells. Does the MLS not need to be on the end? They use TFAM instead of "genegrip".
- Koulintchenko et al. - linear dsDNA - isolated plant mitochondria
- Vestweber et al. - 5' DNA crosslinking with signal sequence - isolated yeast mitochondria
- Seibel et al. - mid-sequence amino-modified deoxythimidine crosslinking with signal sequence - isolated rat liver mitochondria
- Yoon et al. - bacterial conjugation - isolated mouse mitochondria
- Koulintchenko et al. - natural competence - isolated mammalian mitochondria
RNA
- Yeast tRNA - protein complex - in vivo yeast mitochondria
- MRP complex - short RNA-protein complex - in vivo yeast, mammalian mitochondria
- Bhattacharyya et al. - tRNA-like aptamers - Leishmania, isolated mitochondria.
