Batada:Training

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Postdoctoral Fellow (Noncoding RNAs, Epigenetics, Stem Cells)

We are seeking a Postdoctoral Fellow or a Research Associate to use and develop genome-wide methods for identifying novel long noncoding RNAs. Our lab is interested in understanding the role of noncoding RNA in cell fate specification during stem cell differentiation in mouse and human systems.

The ideal candidate will have

  • Good knowledge of molecular biology techniques (nucleic acid manipulation methods and experience working with RNAs),
  • Experience with flow cytometry and immuno-histochemistry
  • Experience with hES and mES tissue culture

The successful candidate will enjoy access to cutting-edge technologies such as Solexa and SOLID sequencers, well-funded and intellectually stimulating environment of OICR's genomic platform, opportunity to drive projects and publish in scientific journals and attend scientific meetings.

Qualifications: Ph.D.in a molecular biology or related field and good english communication skills (oral and written).

Graduate Students (Bioinformatics)

We have an opening for a Graduate student interested in Bioinformatics/Computational Epigenetics applied to Stem Cell and Cancer Biology. Student will have access to raw genome wide sequencing data on DNA methylation, histone modification and single nucleotide and copy number variation.

Questions of interest include the following:

  • Identify the epigenomic/network basis of stem cell pluripotency and self renewal (transcriptional networks of pluripotent transcription factors such as Sox2, Nanog, Oct4, Polycomb and Trithorax proteins)
  • Evolutionary analysis of human and mouse epigenomes
  • Identify epigenetically labile and aberrantly methylated genes in cancer
  • Relate epigenetic modification patterns to gene expression (i.e. decipher the "histone code")
  • Identification and function of regulatory long noncoding RNAs in silencing.

I am open to other related projects as well. Most of these projects require good knowledge of or willingness to learn statistics and programing.

Undergraduates

  • 3rd or 4th year Undergraduates from a Canadian University who are interested in doing summer research (either wetlab or bioinformatics) are encouraged to email me.
  • I am particularly interested in undergraduates in Mathematics, Computer Science or Physics who are interested in mathematical modeling or Bioinformatics

Funding

Postdoctoral Fellowships

  • CIHR, Deadline:october 1st, 40K [1]
  • NSERC, 40K/year for 2 years, deadline: Oct 15/2008 [2]
  • NCIC, Deadline:Feb 1, (Canadian citizen or resident) [3]
  • EMBO Postdoctoral fellowship (For EU) [4]
  • HFSP Postdoctoral fellowship (For Non Canadians) Preregister:Aug 28, Submit: Sept 11[5]

Doctoral Fellowships

Undergraduate