Ben Cosgrove

Lauffenburger Lab

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Ben Cosgrove CV email Ph.D. Student Biological Engineering Division webpage Massachusetts Institute of Technology webpage Research Advisors: Linda Griffith webpage Doug Lauffenburger webpage internal wiki Research Summary: "Multivariate Cue-Signal-Response Analysis of TNFα-Induced Hepatocyte Proliferation and Apoptosis" Quantitative analysis of cell signaling activities and phenotypic cellular outcomes (proliferation, apoptosis, survival) in primary hepatocytes in response to multiple growth factors and cytokines administered in 2D and 3D culture systems. Multivariate signaling activity and proliferation/apoptosis outcome data are analyzed using data-driven methods to explore intracellular and extracellular cross-talk and feedback mechanisms regulating hepatocyte decision-making processes. Member of: MIT Biotechnology Process Engineering center webpage MIT Center for Cell Decision Processes webpage internal wiki MIT Center for Cancer Research webpage Funding: Whitaker Foundation Graduate Research Fellowship webpage MIT-Pfizer Hepatoxicity Signaling Collaboration webpage MIT Center for Cell Decision Processes webpage