BioControl:Future

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Possible topics Local exitation, global inhibition [1] Epigenetics (alternative feedback system) [2] Stochastics [3] Monotone control systems [4], [5] Papers Howard M, Rutenberg AD, and de Vet S. Dynamic compartmentalization of bacteria: accurate division in E. coli. Phys Rev Lett. 2001 Dec 31;87(27 Pt 1):278102. DOI:10.1103/PhysRevLett.87.278102 | Lim HN and van Oudenaarden A. A multistep epigenetic switch enables the stable inheritance of DNA methylation states. Nat Genet. 2007 Feb;39(2):269-75. DOI:10.1038/ng1956 | Mettetal JT, Muzzey D, Pedraza JM, Ozbudak EM, and van Oudenaarden A. Predicting stochastic gene expression dynamics in single cells. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7304-9. DOI:10.1073/pnas.0509874103 | Angeli, D.; Sontag, E.D., "Monotone control systems," Automatic Control, IEEE Transactions on , vol.48, no.10pp. 1684- 1698, Oct. 2003 Ieeexplore Angeli D, Ferrell JE Jr, and Sontag ED. Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1822-7. DOI:10.1073/pnas.0308265100 |