BioControl:Week2-22

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Next meeting 4/29 at 10:30am in the Steele library. Topics Delayed gene regulation Reading Bratsun D, Volfson D, Tsimring LS, and Hasty J. Delay-induced stochastic oscillations in gene regulation. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14593-8. DOI:10.1073/pnas.0503858102 | Related Articles Without any real consequence to the paper, it has been shown that the delayed Gillespie algorithm in the Bratsun paper is not correctly derived. The error is fairly insignificant, and a correct algorithm requires only a tiny correction. So if you ever go to implement something like this, take a glance the paper below, which is poorly communicated but mathematically rigorous: Cai X. Exact stochastic simulation of coupled chemical reactions with delays. J Chem Phys. 2007 Mar 28;126(12):124108. DOI:10.1063/1.2710253 | Discussion