BioSysBio:workshopA1: Difference between revisions
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'''Author(s): '''Herbert Sauro<br> | '''Author(s): '''Herbert Sauro<br> | ||
'''Affiliations: '''University of Washington <br> | '''Affiliations: '''University of Washington <br> | ||
'''Contact: '''hsauro@u.washington | '''Contact: '''hsauro@u.washington.edu<br> | ||
'''Keywords: '''SBW | '''Keywords: '''SBW | ||
Revision as of 05:40, 8 January 2007
Modeling with the Systems Biology Workbench
Author(s): Herbert Sauro
Affiliations: University of Washington
Contact: hsauro@u.washington.edu
Keywords: SBW
Abstract
Modeling biochemical systems requires a wide range of modeling approaches and analysis techniques. In this workshop the approach taken by the Systems Biology Workbench (SBW) will be discussed through examples taken from the modeling of signaling pathways and gene networks. Different modeling approaches will be illustrated including deterministic and stochastic modeling (Gillespie and Langevin). In addition, a range of analysis methods will be employed, such as bifurcation and sensitivity analysis. The SBW is based on the idea of linking disparate tools together, possibly written in different languages so that tools can exploit each others capabilities. The model interchange language used by SBW is the Systems Biology Markup Language (SBML). Some simple examples of how additional tools can be added to SBW will be discussed.
