Biomaterial: Difference between revisions
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Expanded polytetrafluoroethylene (ePTFE), polyethylene terephthalate (Dacron®) and polyurethane are most often used to create artificial blood vessels. They do have a relative stiffness however, and clood clotting is sometimes an issue.(1) | Expanded polytetrafluoroethylene (ePTFE), polyethylene terephthalate (Dacron®) and polyurethane are most often used to create artificial blood vessels. They do have a relative stiffness however, and clood clotting is sometimes an issue.(1) | ||
Polyglycolic acid (PGA), PLLA/polylactide-coglycolide (PLGA), polycaprolactone (PCL), type I collagen, and fibrin are being examined as possible alternatives | Polyglycolic acid (PGA), PLLA/polylactide-coglycolide (PLGA), polycaprolactone (PCL), type I collagen, and fibrin are being examined as possible alternatives. | ||
Blood vessels can also be made by growing it in a lab from endothelium cells (tissue culture). The blood vessels are then self-constructed and are composed of elastin (2). | |||
==Notes== | ==Notes== | ||
1: [http://www.discoveriesinmedicine.com/Apg-Ban/Artificial-Blood-Vessels.html Dacron blood vessels can cause blood clotting, especially when the blood vessels are small in diameter]<br /> | 1: [http://www.discoveriesinmedicine.com/Apg-Ban/Artificial-Blood-Vessels.html Dacron blood vessels can cause blood clotting, especially when the blood vessels are small in diameter]<br /> | ||
2: [https://www.nemokennislink.nl/publicaties/een-reddingsmiddel-voor-dwarsliggende-vaten Mark Post from UMC Maastricht succeeded in making blood vessels from endothelium cells]<br /> | |||
==See also== | ==See also== | ||
*[[3D bioprinting]] | *[[3D bioprinting]] |
Latest revision as of 10:22, 17 May 2017
A biomaterial or biocompatible material is a biological or synthetic material that is not rejected by the body when introduced into the body.
Use
Biomaterials are used to make:
- blood vessels (arteries, ...)
- joint replacements
- ligaments and tendons
- vascular grafts
- heart valves
- ...
Materials often used
For joints: Titanium is most often used
For bone reconstruction Alginate is often used
For blood vessels: Expanded polytetrafluoroethylene (ePTFE), polyethylene terephthalate (Dacron®) and polyurethane are most often used to create artificial blood vessels. They do have a relative stiffness however, and clood clotting is sometimes an issue.(1)
Polyglycolic acid (PGA), PLLA/polylactide-coglycolide (PLGA), polycaprolactone (PCL), type I collagen, and fibrin are being examined as possible alternatives.
Blood vessels can also be made by growing it in a lab from endothelium cells (tissue culture). The blood vessels are then self-constructed and are composed of elastin (2).
Notes
1: Dacron blood vessels can cause blood clotting, especially when the blood vessels are small in diameter
2: Mark Post from UMC Maastricht succeeded in making blood vessels from endothelium cells