Biomaterial: Difference between revisions

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Expanded polytetrafluoroethylene (ePTFE), polyethylene terephthalate (Dacron®) and polyurethane are most often used to create artificial blood vessels. They do have a relative stiffness however, and clood clotting is sometimes an issue.(1)  
Expanded polytetrafluoroethylene (ePTFE), polyethylene terephthalate (Dacron®) and polyurethane are most often used to create artificial blood vessels. They do have a relative stiffness however, and clood clotting is sometimes an issue.(1)  


Polyglycolic acid (PGA), PLLA/polylactide-coglycolide (PLGA), polycaprolactone (PCL), type I collagen, and fibrin are being examined as possible alternatives
Polyglycolic acid (PGA), PLLA/polylactide-coglycolide (PLGA), polycaprolactone (PCL), type I collagen, and fibrin are being examined as possible alternatives.
 
Blood vessels can also be made by growing it in a lab from endothelium cells (tissue culture). The blood vessels are then self-constructed and are composed of elastin (2).


==Notes==
==Notes==
1: [http://www.discoveriesinmedicine.com/Apg-Ban/Artificial-Blood-Vessels.html Dacron blood vessels can cause blood clotting, especially when the blood vessels are small in diameter]<br />
1: [http://www.discoveriesinmedicine.com/Apg-Ban/Artificial-Blood-Vessels.html Dacron blood vessels can cause blood clotting, especially when the blood vessels are small in diameter]<br />
2: [https://www.nemokennislink.nl/publicaties/een-reddingsmiddel-voor-dwarsliggende-vaten Mark Post from UMC Maastricht succeeded in making blood vessels from endothelium cells]<br />


==See also==
==See also==
*[[3D bioprinting]]
*[[3D bioprinting]]

Latest revision as of 10:22, 17 May 2017

A biomaterial or biocompatible material is a biological or synthetic material that is not rejected by the body when introduced into the body.

Use

Biomaterials are used to make:

  • blood vessels (arteries, ...)
  • joint replacements
  • ligaments and tendons
  • vascular grafts
  • heart valves
  • ...

Materials often used

For joints: Titanium is most often used

For bone reconstruction Alginate is often used

For blood vessels: Expanded polytetrafluoroethylene (ePTFE), polyethylene terephthalate (Dacron®) and polyurethane are most often used to create artificial blood vessels. They do have a relative stiffness however, and clood clotting is sometimes an issue.(1)

Polyglycolic acid (PGA), PLLA/polylactide-coglycolide (PLGA), polycaprolactone (PCL), type I collagen, and fibrin are being examined as possible alternatives.

Blood vessels can also be made by growing it in a lab from endothelium cells (tissue culture). The blood vessels are then self-constructed and are composed of elastin (2).

Notes

1: Dacron blood vessels can cause blood clotting, especially when the blood vessels are small in diameter
2: Mark Post from UMC Maastricht succeeded in making blood vessels from endothelium cells

See also