Biomod/2011/Harvard/HarvarDNAnos:LabNotebook Nick/2011/06/06: Difference between revisions

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|style="background-color: #cdde95"|[[Image:owwnotebook_icon.png|128px]]<span style="font-size:22px;"> Nick's Lab Notebook </span>
|style="background-color: #cdde95"|[[Image:owwnotebook_icon.png|128px]]<span style="font-size:22px;"> Nick's Lab Notebook </span>
|style="background-color: #F2F2F2" align="center"|<html><img src="/images/9/94/Report.png" border="0" /></html> [[{{#sub:{{FULLPAGENAME}}|0|-11}}|Main project page]]<br />{{#if:{{#lnpreventry:{{FULLPAGENAME}}}}|<html><img src="/images/c/c3/Resultset_previous.png" border="0" /></html>[[{{#lnpreventry:{{FULLPAGENAME}}}}{{!}}Previous entry]]<html>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</html>}}{{#if:{{#lnnextentry:{{FULLPAGENAME}}}}|[[{{#lnnextentry:{{FULLPAGENAME}}}}{{!}}Next entry]]<html><img src="/images/5/5c/Resultset_next.png" border="0" /></html>}}
|style="background-color: #F2F2F2" align="center"|<html><img src="/images/9/94/Report.png" border="0" /></html> [[{{#sub:{{FULLPAGENAME}}|0|-11}}|Nick's Lab Notebook Homepage]]<br />{{#if:{{#lnpreventry:{{FULLPAGENAME}}}}|<html><img src="/images/c/c3/Resultset_previous.png" border="0" /></html>[[{{#lnpreventry:{{FULLPAGENAME}}}}{{!}}Previous entry]]<html>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</html>}}{{#if:{{#lnnextentry:{{FULLPAGENAME}}}}|[[{{#lnnextentry:{{FULLPAGENAME}}}}{{!}}Next entry]]<html><img src="/images/5/5c/Resultset_next.png" border="0" /></html>}}
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Latest revision as of 18:52, 27 June 2011

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Monday (2011-06-06)

  • This morning we began with a brainstorming session and discussed a few different box designs that we hope to represent as caDNAno files.
  • Throughout the day, I designed a six sided box with parallel helices and a hole in one side. My initial inclination is to create a staple-lock-staple mesh over the designed hole to contain cargo that is loaded into the box pre-folding. This mesh could (irreversibly) be removed using a key strand or a designed restriction enzyme site at staple-staple interfaces.
Perkons_Box1.json
  • Below is one of the scariest looking caDNAno screens after hitting auto-staple

  • Below is a screenshot of the cleaner, and much less intimidating, CanDo output. It looks like the design was a success! Now to design a cover for the hole that can be opened by a separate mechanism...



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