Biomod/2011/Harvard/HarvarDNAnos:Mission

From OpenWetWare
Jump to navigationJump to search

<html> <head> 

 <style>
  1. column-one { display:none; width:0px;}

.container{background-color: #f5f5f5; margin-top:50px} .OWWNBcpCurrentDateFilled {display: none;}

  1. content {width: 0px; margin: 0 auto auto 0; padding: 1em 1em 1em 1em; align: center;}
  2. column-content {width: 0px; float: left; margin: 0 0 0 0;padding: 0;}

.firstHeading {display:none; width:0px;}

  1. globalWrapper{width:1280px; margin:auto}

body {background: #F0F0F0 !important;}

  1. column-one {display:none; width:0px;background-color: #f0f0f0;}
  2. content{border:none;margin: 0 0 0 0; padding: 1em 1em 1em 1em; position: center; width: 800px;background-color: #f0f0f0; }

.container{ width: 800px; margin: auto; background-color: #f0f0f0; text-align:justify; font-family: helvetica, arial, sans-serif; color:#f0f0f0; margin-top:25px; }

  1. bodyContent{ width: 1267px; align: center; background-color: #f0f0f0;}
  2. column-content{width: 1280px;background-color: #f0f0f0;}

.firstHeading { display:none;width:0px;background-color: #f0f0f0;}

  1. header{position: center; width: 800px;background-color: #f0f0f0;}
  2. footer{position: center; width:1280px;}
 </style>

</head> </html>

<html><center><a href='http://openwetware.org/wiki/Biomod/2011/Harvard/HarvarDNAnos'><img src=http://openwetware.org/images/1/1c/Hdnaheader.jpg width=800px></a></center></html>

Home              Mission              Process              Designs              Results              Resources              Team

Motivation

At the beginning of summer, there were two ideas that particularly excited us (and continue to excite us today):

  1. the development of "nano-submarines" (Figure 1) that could programmably deliver and release drugs to, for example, specific parts of the body or specific parts of the cell, and
  2. the realization of a one-step detection and amplification system (Figure 2) that could be deployed to augment the efficiency of catalytic DNA circuits or simplify the assay of molecular or heavy metal signals.


Figure 1. "Nano-submarine"
Figure 2. Simultaneous detection and amplification

Here is our brainstorming.

Inspiration

Goals

Therefore, our goal is to create DNA origami containers that can load, hold, and release cargo. To do this, we aim to:

  1. Load various forms of cargo by attaching it to the inside of a container and then closing the container
  2. Solubilize this cargo without leakage to the exterior of the container
  3. Open our container, releasing our cargo
Retrieved from "https://openwetware.org/mediawiki/index.php?title=Biomod/2011/Harvard/HarvarDNAnos:Mission&oldid=547923"