Biomod/2011/TeamJapan/Tokyo: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
<!--この上の呪文たちは必ず各ページのコピペすること--> | <!--この上の呪文たちは必ず各ページのコピペすること--> | ||
=Project overview= | =Project overview= | ||
Revision as of 10:37, 1 November 2011
Project overview
<html><body><table width="100%"><tr><td width="500px" valign="top" style="padding-left:20px"> <br><i>TeamJapan Tokyo developed an autonomous micrometer-sized molecular robot, “DNA ciliate”, toward the construction of a highly functional molecular robot like a living cell.</i><br><br> A living cell is an ultimate highly functional molecular robot. The high functionality results from not only its various functional molecules but also its “micrometer-sized” body that has enough space to possess the molecules. However, the sizes of already-developed molecular nanomachines are too small to include many functional molecules. Toward the construction of highly functional molecular machines and molecular robots, it is required to construct molecular robots with large (i.e., micrometer-sized) bodies. Here, we propose an autonomous micrometer-sized molecular robot “DNA ciliate”. A natural ciliate has a micrometer-sized body with cilia and achieves various functions such as autonomous motion with the cilia, phototaxis, etc. <b>DNA ciliate has a micrometer-sized body with many DNAs as cilia</b>, and it can switch three different modes in response to its external environment: <b>the free moving mode, the track walking mode, and the light-irradiated gathering mode</b>. (See below.) </td><td align="center" valign="top"> <a href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo/Project"><img src="http://openwetware.org/images/2/2c/Biomod2011_Team_Tokyo_111101Biomod_three_mode_02_R.jpg" border=1 width="350" height="263"></a><br>
<font size="3" color="#000066"><i><strong>
<font size="3" color="#00ff66">“DNA ciliate”</font>is an autonomous micrometer-sized molecular robot that has three independent functional modes. </strong></i></font><br><br><iframe width="350" height="263" src="http://www.youtube.com/embed/uejCuQWG07A" frameborder="0" allowfullscreen></iframe>
</td> </tr>
</table> </body></html>
DNA ciliate body
|
|
 |
 |
 |
| The free moving mode is utilizing Brownian motion. We changed the size of DNA ciliate and observed the DNA ciliate movement by Brownian motion. | The track walking mode is utilizing deoxyribozyme activity for substrate. We checked deoxyribozyme activity and simulated DNA ciliate movement on micrometer-sized track and confirmed the track walking mode by simulation. | The light-irradiated gathering mode is utilizing UV-switching DNA. We checked the "UV-switching system" and confirmed DNA ciliate trapping at one spot. |
