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<div id="navigation"> <div id="menu" style="position:static"> <ul> <li><a class="aMain" href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo">Home</a></li> <li><a class="aTeam" href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo/Team/Students">Team</a></li> <li><a class="aProject" href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo/Project">Project</a>  <li><font color="#ffffff">Results</font> <ul> <li><a href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo/Project/Results">Experiments</a></li> <li><a href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo/Project/Simulations">Simulations</a></li> <li><a href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo/Achievements/DNA_Devices">DNA Design</a></li> </ul></li>  <li><a href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo/Project/Achievements">Achievements</a></li> <li><a href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo/Project/Future_works">Future works</a></li> <li><a href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo/Notebook/Protocols">Protocols</a></li> <li><a href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo/Notebook/Lab.notebook">Notes</a></li> <li><a class="aNotebook" href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo/Sponsors/">Sponsors</a></li> <li><a class="aSitemap" href="http://openwetware.org/wiki/Biomod/2011/TeamJapan/Tokyo/Sitemap">Sitemap</a></li>

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Future works

In this time, we fabricated the model of the cell size huge molecular robot called “DNA ciliate”. The model is actuated by Brownian motion and DNA control strands that trigger Hybridization, which includes a DNA-zyme action and a branch migration, and stopped by light irradiation that occurs to an azobenzene structural change. Using these principles, we realized the system switching from Brownian diffusion state to an assembly state. This can be also read the transport technology that controls micro-size substances using a mass of nano-size DNAs. It is expected not only the transport but also many interesting applications; autonomous DNA robots, new integrate method, information science and so on.

For example, the macro-size circulatory DNA robot, which directly implants some functional nano systems into a liposome, could had highly functions and be applied to the medical technology that continuously circulates through human blood vessels, detects and treats a focus with incorporated systems.

Another example is the new method of integrated circuits. It's recently imperative to establish the next generation of integration technologies, because it's just a matter of time before the limit (25nm) of integrated circuits is achieved by top-down techniques. This value is made a prediction by Moore's Law. Here, we developed the way of gathering DNA cilia to an objective place. This skill could apply to the integration and break through the limitation, if we use it to assemble the structures having metal particles to arbitrary points and with optional quantities, causing some kind or another chemical reaction and building a narrow range of a circuit.

The third is a newly drug delivery system (DDS). Now, we constructed the transport system that huge micro objects are transported by many nano things. Using the mechanism, we expect that a DNA ciliate furnished extremely small drugs, which fixed in ciliate surface and had individual reactions, serves around several focuses, corresponding to drugs.

As can be seen, our facture has a lot of diversity. This is why our robot has two aspects. One is a controlled objects, another is that it has a certain level of autonomy. In the future, Taking advantage of these characteristics, we expect that they could apply the completely chemical control and Life Sciences, medical, information science and integrated technology and so on.

Biomod/2011/TeamJapan/Tokyo/Project/Future works

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