Biomod/2012/Harvard/BioDesign/approaches: Difference between revisions
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[[Biomod/2012/Harvard/BioDesign/small_canvas_SST |a small SST canvas]], | [[Biomod/2012/Harvard/BioDesign/small_canvas_SST |a small SST canvas]], | ||
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[[Biomod/2012/Harvard/BioDesign/large_canvas_SST |a large SST canvas]], | [[Biomod/2012/Harvard/BioDesign/large_canvas_SST |a large SST canvas]], and | ||
<br> | <br> | ||
[[Biomod/2012/Harvard/BioDesign/DNA_origami |a 3D-DNA origami structure]]. | |||
<br> | <br> | ||
The other component of our project was to optimize the design for the L-DNA layer and how to attach it to the template. A design note was that we also wanted to lower the melting point of the strands so that we could anneal that part on without affecting our pre-formed template. Here is our work on the [[Biomod/2012/Harvard/BioDesign/L-DNA_layer |L-DNA layer]]. | The other component of our project was to optimize the design for the L-DNA layer and how to attach it to the template. A design note was that we also wanted to lower the melting point of the strands so that we could anneal that part on without affecting our pre-formed template. Here is our work on the [[Biomod/2012/Harvard/BioDesign/L-DNA_layer |L-DNA layer]]. |
Revision as of 01:23, 27 October 2012
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Approaches
Our project had multiple parallel pathways. There were two sub-problems to solve in approaching the templating problem.
One was the templating technique, for which we experimented with three different D-DNA designs;
a small SST canvas,
a large SST canvas, and
a 3D-DNA origami structure.
The other component of our project was to optimize the design for the L-DNA layer and how to attach it to the template. A design note was that we also wanted to lower the melting point of the strands so that we could anneal that part on without affecting our pre-formed template. Here is our work on the L-DNA layer.